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公开(公告)号:US20080161902A1
公开(公告)日:2008-07-03
申请号:US12005178
申请日:2007-12-26
申请人: Flemming Poulsen
发明人: Flemming Poulsen
CPC分类号: A61F2/95 , A61M2025/0681 , A61M2025/0687
摘要: A stent delivery sheath has a distal portion extending circumferentially around a stent, the delivery sheath tapering distally of the stent to a reduced diameter at the distal end of the sheath so providing an atraumatic or dilating surface distally of the stent. The distal portion of the delivery sheath comprises a low friction inner layer and an elastic outer layer both extending to the distal end of the sheath. The inner layer has at least one separation line extending longitudinally of the sheath to the distal end to define at least two leaf edges in the radially inner layer which are configured to move circumferentially with respect to each other to accommodate elastic radial expansion of the outer layer as the sheath is retracted proximally with respect to the stent.
摘要翻译: 支架输送护套具有围绕支架周向延伸的远侧部分,所述输送护套在支架的远端逐渐变细到在护套的远端处的直径减小,从而在支架的远端提供无损伤或扩张的表面。 输送护套的远端部分包括一个低摩擦内层和两个延伸到护套远端的弹性外层。 所述内层具有至少一个分离线,所述分离线从所述护套的纵向延伸到所述远端以限定所述径向内层中的至少两个叶边缘,所述至少两个叶边缘被配置成相对于彼此周向移动以适应所述外层的弹性径向膨胀 因为护套相对于支架向近侧缩回。
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公开(公告)号:US20050153888A1
公开(公告)日:2005-07-14
申请号:US10992287
申请日:2004-11-19
申请人: Lars Christian Ronn , Arne Holm , Marianne Olsen , Soren Ostergaard , Peter Jensen , Flemming Poulsen , Vladislav Soroka , Igor Ralets , Vladimir Berezin , Elisabeth Bock
发明人: Lars Christian Ronn , Arne Holm , Marianne Olsen , Soren Ostergaard , Peter Jensen , Flemming Poulsen , Vladislav Soroka , Igor Ralets , Vladimir Berezin , Elisabeth Bock
IPC分类号: C12N15/09 , A61K38/00 , A61K38/39 , A61K39/395 , A61K45/00 , A61P1/00 , A61P1/16 , A61P1/18 , A61P3/10 , A61P9/00 , A61P9/10 , A61P13/12 , A61P15/08 , A61P21/00 , A61P25/00 , A61P25/02 , A61P25/16 , A61P25/18 , A61P25/28 , A61P43/00 , C07K7/08 , C07K14/705 , C07K14/78 , C07K16/42 , C07K16/46 , C12P21/08 , A61K38/17 , C07K14/47
CPC分类号: C07K14/70503 , A61K38/00
摘要: The invention provides novel compounds which are capable of stimulating the proliferation or/and the outgrowth from cells presenting the neural cell adhesion molecule (NCAM). Additionally, the invention relates to methods for treatment of normal, degenerated and damaged NCAM presenting cells.
摘要翻译: 本发明提供能够刺激呈递神经细胞粘附分子(NCAM)的细胞的增殖和/或生长的新型化合物。 此外,本发明涉及用于治疗正常,退化和损伤的NCAM呈递细胞的方法。
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公开(公告)号:US20050222041A1
公开(公告)日:2005-10-06
申请号:US10488517
申请日:2002-09-04
申请人: Lars Biilmann , Marianne Olsen , Elisabeth Bock , Vladimir Berezin , Flemming Poulsen , Arne Holm , Vladislav Soroka , Soren Ostergaard
发明人: Lars Biilmann , Marianne Olsen , Elisabeth Bock , Vladimir Berezin , Flemming Poulsen , Arne Holm , Vladislav Soroka , Soren Ostergaard
IPC分类号: C12N5/02 , A61K38/00 , A61L27/00 , A61P1/00 , A61P1/16 , A61P1/18 , A61P3/10 , A61P9/00 , A61P13/12 , A61P15/00 , A61P17/02 , A61P21/04 , A61P25/00 , A61P25/02 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/24 , A61P25/28 , A61P35/00 , A61P43/00 , C07K4/00 , C07K7/00 , C07K7/06 , C07K14/00 , A61K38/08
CPC分类号: C07K7/06
摘要: The present invention concerns an NCAM (neural cell adhesion molecule) binding peptide capable of stimulating NCAM signalling and/or interfering with cell adhesion. The compound may be used for the treatment of diseases or conditions of the central and peripheral nervous system.
摘要翻译: 本发明涉及能够刺激NCAM信号传导和/或干扰细胞粘附的NCAM(神经细胞粘附分子)结合肽。 该化合物可用于治疗中枢和周围神经系统的疾病或病症。
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