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公开(公告)号:US20050153888A1
公开(公告)日:2005-07-14
申请号:US10992287
申请日:2004-11-19
申请人: Lars Christian Ronn , Arne Holm , Marianne Olsen , Soren Ostergaard , Peter Jensen , Flemming Poulsen , Vladislav Soroka , Igor Ralets , Vladimir Berezin , Elisabeth Bock
发明人: Lars Christian Ronn , Arne Holm , Marianne Olsen , Soren Ostergaard , Peter Jensen , Flemming Poulsen , Vladislav Soroka , Igor Ralets , Vladimir Berezin , Elisabeth Bock
IPC分类号: C12N15/09 , A61K38/00 , A61K38/39 , A61K39/395 , A61K45/00 , A61P1/00 , A61P1/16 , A61P1/18 , A61P3/10 , A61P9/00 , A61P9/10 , A61P13/12 , A61P15/08 , A61P21/00 , A61P25/00 , A61P25/02 , A61P25/16 , A61P25/18 , A61P25/28 , A61P43/00 , C07K7/08 , C07K14/705 , C07K14/78 , C07K16/42 , C07K16/46 , C12P21/08 , A61K38/17 , C07K14/47
CPC分类号: C07K14/70503 , A61K38/00
摘要: The invention provides novel compounds which are capable of stimulating the proliferation or/and the outgrowth from cells presenting the neural cell adhesion molecule (NCAM). Additionally, the invention relates to methods for treatment of normal, degenerated and damaged NCAM presenting cells.
摘要翻译: 本发明提供能够刺激呈递神经细胞粘附分子(NCAM)的细胞的增殖和/或生长的新型化合物。 此外,本发明涉及用于治疗正常,退化和损伤的NCAM呈递细胞的方法。
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公开(公告)号:US06887844B1
公开(公告)日:2005-05-03
申请号:US09787443
申请日:1999-09-23
申请人: Lars Christian Ronn , Arne Holm , Marianne Olsen , Soren Ostergaard , Peter H. Jensen , Flemming M. Poulsen , Vladislav Soroka , Igor Ralets , Vladimir Berezin , Elisabeth Bock
发明人: Lars Christian Ronn , Arne Holm , Marianne Olsen , Soren Ostergaard , Peter H. Jensen , Flemming M. Poulsen , Vladislav Soroka , Igor Ralets , Vladimir Berezin , Elisabeth Bock
IPC分类号: C12N15/09 , A61K38/00 , A61K38/39 , A61K39/395 , A61K45/00 , A61P1/00 , A61P1/16 , A61P1/18 , A61P3/10 , A61P9/00 , A61P9/10 , A61P13/12 , A61P15/08 , A61P21/00 , A61P25/00 , A61P25/02 , A61P25/16 , A61P25/18 , A61P25/28 , A61P43/00 , C07K7/08 , C07K14/705 , C07K14/78 , C07K16/42 , C07K16/46 , C12P21/08 , A61K38/04 , C07K7/00
CPC分类号: C07K14/70503 , A61K38/00
摘要: The invention provides novel compounds which are capable to stimulate the proliferation or/and the outgrowth from cells presenting the neural cell adhesion molecule (NCAM). Additionally, the invention relates to pharmaceutical compositions, medicaments and methods for treatment of normal, degenerated and damaged NCAM presenting cells.
摘要翻译: 本发明提供能够刺激来自呈递神经细胞粘附分子(NCAM)的细胞的增殖和/或生长的新型化合物。 此外,本发明涉及用于治疗正常,退化和损伤的NCAM呈递细胞的药物组合物,药物和方法。
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公开(公告)号:US07402560B2
公开(公告)日:2008-07-22
申请号:US10992287
申请日:2004-11-19
申请人: Lars Christian Ronn , Arne Holm , Marianne Olsen , Soren Ostergaard , Peter H. Jensen , Flemming M. Poulsen , Vladislav Soroka , Igor Ralets , Vladimir Berezin , Elisabeth Bock
发明人: Lars Christian Ronn , Arne Holm , Marianne Olsen , Soren Ostergaard , Peter H. Jensen , Flemming M. Poulsen , Vladislav Soroka , Igor Ralets , Vladimir Berezin , Elisabeth Bock
IPC分类号: C07K14/435 , C07K14/705 , A61K38/00 , A61K38/04
CPC分类号: C07K14/70503 , A61K38/00
摘要: The invention provides novel compounds which are capable of stimulating the proliferation or/and the outgrowth from cells presenting the neural cell adhesion molecule (NCAM). Additionally, the invention relates to methods for treatment of normal, degenerated and damaged NCAM presenting cells.
摘要翻译: 本发明提供能够刺激呈递神经细胞粘附分子(NCAM)的细胞的增殖和/或生长的新型化合物。 此外,本发明涉及用于治疗正常,退化和损伤的NCAM呈递细胞的方法。
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公开(公告)号:US20050222041A1
公开(公告)日:2005-10-06
申请号:US10488517
申请日:2002-09-04
申请人: Lars Biilmann , Marianne Olsen , Elisabeth Bock , Vladimir Berezin , Flemming Poulsen , Arne Holm , Vladislav Soroka , Soren Ostergaard
发明人: Lars Biilmann , Marianne Olsen , Elisabeth Bock , Vladimir Berezin , Flemming Poulsen , Arne Holm , Vladislav Soroka , Soren Ostergaard
IPC分类号: C12N5/02 , A61K38/00 , A61L27/00 , A61P1/00 , A61P1/16 , A61P1/18 , A61P3/10 , A61P9/00 , A61P13/12 , A61P15/00 , A61P17/02 , A61P21/04 , A61P25/00 , A61P25/02 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/24 , A61P25/28 , A61P35/00 , A61P43/00 , C07K4/00 , C07K7/00 , C07K7/06 , C07K14/00 , A61K38/08
CPC分类号: C07K7/06
摘要: The present invention concerns an NCAM (neural cell adhesion molecule) binding peptide capable of stimulating NCAM signalling and/or interfering with cell adhesion. The compound may be used for the treatment of diseases or conditions of the central and peripheral nervous system.
摘要翻译: 本发明涉及能够刺激NCAM信号传导和/或干扰细胞粘附的NCAM(神经细胞粘附分子)结合肽。 该化合物可用于治疗中枢和周围神经系统的疾病或病症。
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