公开(公告)号：US20160228700A1

公开(公告)日：2016-08-11

申请号：US15132270

申请日：2016-04-19

申请人： MORDECHAY ESH ,  GIORA ARBEL

发明人： MORDECHAY ESH ,  GIORA ARBEL

IPC分类号： A61N1/36 ,  A61N1/32 ,  A61N1/04

CPC分类号： A61N1/36007 ,  A61N1/0452 ,  A61N1/0476 ,  A61N1/0484 ,  A61N1/18 ,  A61N1/321 ,  A61N1/36 ,  A61N1/36014

摘要： A non-invasive device for facilitating therapy of patient suffering from the gastrointestinal system diseases or symptoms, and in particular suffering Gastroesophageal reflux disease (GERD). The device is positioned by the patient on the skin of the patient abdomen and electrically stimulates the abdomen muscles. This treating results in dynamic motions of the digestive system, which causes the treatment of various digestive symptoms or diseases.

摘要翻译： 用于促进患有胃肠系统疾病或症状的患者，特别是患有胃食管反流病（GERD）的患者的非侵入性装置。 该装置由患者定位在患者腹部的皮肤上并电刺激腹部肌肉。 这种治疗导致消化系统的动态运动，其导致各种消化症状或疾病的治疗。

公开(公告)号：US06567706B2

公开(公告)日：2003-05-20

申请号：US09811613

申请日：2001-03-20

申请人： Jonathan Bar-Or ,  Giora Arbel

发明人： Jonathan Bar-Or ,  Giora Arbel

IPC分类号： A61N100

CPC分类号： A61N1/0452 ,  A61N1/0472 ,  A61N1/0492 ,  A61N1/0496

摘要： The invention provides an electrode kit for muscle stimulation to be used in conjunction with a splint, the kit including an electrode carrier attachable to an interior surface of the splint and consisting of a relatively thin, flexible, tray-like member; a thin, flexible electrode member fixedly attached to the electrode carrier, and a skin-contacting pad member consisting of a piece of medium-absorptive material fixedly mounted on a rigidifying frame attachable to, and removable from, the electrode carrier.

摘要翻译： 本发明提供了一种用于肌肉刺激的电极套件，其与夹板一起使用，该套件包括可附接到夹板的内表面并由相对薄的，柔性的托盘状构件构成的电极载体; 固定地附接到电极载体上的薄而柔性的电极部件，以及皮肤接触垫部件，其由固定地安装在可附接到电极载体上并可从电极载体移除的刚性框架上的一块介质吸收材料构成。

公开(公告)号：US10661081B2

公开(公告)日：2020-05-26

申请号：US15915255

申请日：2018-03-08

申请人： Mordechay Esh ,  Giora Arbel

发明人： Mordechay Esh ,  Giora Arbel

IPC分类号： A61N1/00 ,  A61N1/36 ,  A61N1/04 ,  A61N1/18 ,  A61N1/32

摘要： A non-invasive method and device for treating gastroesophageal reflux disease (GERD) in a patient are disclosed. The method calls for positioning electrodes, and applying electrical symmetrical bursts. In particular, positioning step requires positioning a plurality of electrodes in electrical contact with the skin of a target region of the abdomen of the patient. The application step calls for applying a series of electrical symmetrical bursts to said electrodes. That application step generates contractions of abdominal muscles thereby generating movements of a digestive system of said patient wherein said movements are for causing the content of the esophagus to return to the stomach and to relieve GERD symptoms of said patient.

公开(公告)号：US20100286588A1

公开(公告)日：2010-11-11

申请号：US12682291

申请日：2008-10-12

申请人： Yossi Bar-El ,  Giora Arbel

发明人： Yossi Bar-El ,  Giora Arbel

IPC分类号： A61N1/20

CPC分类号： A61N1/327 ,  A61N1/0424 ,  A61N1/044

摘要： Apparatus is described for facilitating delivery of a substance through skin (70) of a subject. A skin preparation device (50), and a patch assembly (20) that comprises the substance and is magnetically couplable to the skin preparation device, are described. Other embodiments are also described.

摘要翻译： 描述了用于促进物质通过受试者的皮肤（70）递送的装置。 描述了皮肤制备装置（50）和包括该物质并且与皮肤准备装置可磁耦合的补片组件（20）。 还描述了其它实施例。

公开(公告)号：US09037229B2

公开(公告)日：2015-05-19

申请号：US12682291

申请日：2008-10-12

申请人： Yossi Bar-El ,  Giora Arbel

发明人： Yossi Bar-El ,  Giora Arbel

IPC分类号： A61N1/30 ,  A61N1/32 ,  A61N1/04

CPC分类号： A61N1/327 ,  A61N1/0424 ,  A61N1/044

摘要： Apparatus is described for facilitating delivery of a substance through skin (70) of a subject. A skin preparation device (50), and a patch assembly (20) that comprises the substance and is magnetically couplable to the skin preparation device, are described. Other embodiments are also described.

摘要翻译： 描述了用于促进物质通过受试者的皮肤（70）递送的装置。 描述了皮肤制备装置（50）和包括该物质并且与皮肤准备装置可磁耦合的补片组件（20）。 还描述了其它实施例。

公开(公告)号：US07922676B2

公开(公告)日：2011-04-12

申请号：US10936540

申请日：2004-09-09

申请人： Shalom Daskal ,  Dov Tamarkin ,  Zvi Nitzan ,  Nurit Harel ,  Daniela Mavor ,  Giora Arbel ,  Shalom Luski ,  Noam Emanuel ,  Dalia Jayes

发明人： Shalom Daskal ,  Dov Tamarkin ,  Zvi Nitzan ,  Nurit Harel ,  Daniela Mavor ,  Giora Arbel ,  Shalom Luski ,  Noam Emanuel ,  Dalia Jayes

IPC分类号： A61F5/00

CPC分类号： A61N1/326 ,  A61N1/0436 ,  A61N1/044 ,  A61N1/0448 ,  A61N1/325

摘要： The present invention provides a device and kit and method of use thereof for wound treatment of a subject. The device may include an electrically operated patch or other means of delivery of electrical current and a connected moist surface. Optionally, the device may include a composition comprising an active substance useful in wound treatment. Preferably, the means of delivery of electrical current includes a power source and a plurality of electrodes disposed in a suitable conformation on a base substrate layer, which readily facilitates electrical contact with the body area of the subject. Preferably, the kit may include a means of delivery of electrical current and a moist surface provided as separate components.The present invention further provides a thin and flexible device for galvanic treatment to treat wounds with electrical stimulation. Preferably, the device is made using a printing technique.

摘要翻译： 本发明提供了一种用于受试者的伤口治疗的装置和试剂盒及其使用方法。 该装置可以包括电操作的贴片或电流的其它输送装置和连接的潮湿表面。 任选地，装置可以包括包含可用于伤口治疗的活性物质的组合物。 优选地，电流传递装置包括电源和在基底层上以适当构型设置的多个电极，其容易地促进与受试者身体区域的电接触。 优选地，套件可以包括递送电流的装置和作为单独部件提供的潮湿表面。 本发明还提供了一种薄而灵活的电气处理装置，用电刺激来治疗伤口。 优选地，使用印刷技术制造该装置。

公开(公告)号：US20100293807A1

公开(公告)日：2010-11-25

申请号：US12740184

申请日：2008-10-29

申请人： Yossi Bar-El ,  Giora Arbel ,  Meir Stern

发明人： Yossi Bar-El ,  Giora Arbel ,  Meir Stern

IPC分类号： F26B21/08 ,  F26B21/00 ,  F26B5/00

CPC分类号： F26B21/12 ,  F26B21/004 ,  F26B21/08 ,  F26B21/14

摘要： Apparatus is provided, including one or more drug patches (20) and a surface (22) configured to hold the one or more drug patches. A housing (24) is shaped to define one or more gas inflow openings (30) that are configured to facilitate drying of the patches by directing a flow of a gas toward the patches, a midline of the flow being at an angle of less than 20 degrees from a normal to the surface. Other embodiments are also described.

摘要翻译： 提供了包括一个或多个药物贴片（20）和被配置为保持一个或多个药物贴片的表面（22）的装置。 壳体（24）被成形为限定一个或多个气体流入开口（30），其被构造成便于通过将气流朝着贴片引导来促进贴片的干燥，流体的中线处于小于 从正常到表面20度。 还描述了其它实施例。

公开(公告)号：US07483738B2

公开(公告)日：2009-01-27

申请号：US10724054

申请日：2003-12-01

申请人： Dov Tamarkin ,  Zvi Nitzan ,  Giora Arbel ,  Daniela Mavor ,  Yossif Gross ,  Shalom Luski

发明人： Dov Tamarkin ,  Zvi Nitzan ,  Giora Arbel ,  Daniela Mavor ,  Yossif Gross ,  Shalom Luski

IPC分类号： A61N1/30

CPC分类号： A61N1/323 ,  A61N1/0428 ,  A61N1/30 ,  A61N1/325 ,  A61N1/328 ,  A61N1/36021

摘要： The present invention is of an apparatus and method for enhancing skin, muscle and nerve stimulation and controlled delivery of an active substance to a subject's skin. Moreover, the present invention is of an apparatus, featuring a combination of a stimulating device and an exothermic heating source. Preferably, the stimulating device is an iontophoretic device, or an electrical stimulation device, such as, but not limited to TENS, IFC and GC devices or a combination thereof. The present invention also provides a method of using such an apparatus for enhancing skin, muscle and nerve stimulation. Furthermore, the present invention provides a method of use of such an apparatus for enhancing controlled delivery of an active substance.

摘要翻译： 本发明是一种用于增强皮肤，肌肉和神经刺激并将活性物质控制递送到受试者的皮肤的装置和方法。 此外，本发明是一种以刺激装置和放热加热源的组合为特征的装置。 优选地，刺激装置是离子电渗疗法装置或电刺激装置，例如但不限于TENS，IFC和GC装置或其组合。 本发明还提供了一种使用这种装置来增强皮肤，肌肉和神经刺激的方法。 此外，本发明提供了一种使用这种用于增强活性物质的受控递送的装置的方法。

公开(公告)号：US09925375B2

公开(公告)日：2018-03-27

申请号：US15132270

申请日：2016-04-19

申请人： Mordechay Esh ,  Giora Arbel

发明人： Mordechay Esh ,  Giora Arbel

IPC分类号： A61N1/00 ,  A61N1/36 ,  A61N1/18 ,  A61N1/04 ,  A61N1/32

CPC分类号： A61N1/36007 ,  A61N1/0452 ,  A61N1/0476 ,  A61N1/0484 ,  A61N1/18 ,  A61N1/321 ,  A61N1/36 ,  A61N1/36014

摘要： A non-invasive device for facilitating therapy of patient suffering from the gastrointestinal system diseases or symptoms, and in particular suffering Gastroesophageal reflux disease (GERD). The device is positioned by the patient on the skin of the patient abdomen and electrically stimulates the abdomen muscles. This treating results in dynamic motions of the digestive system, which causes the treatment of various digestive symptoms or diseases.

公开(公告)号：US20130211347A1

公开(公告)日：2013-08-15

申请号：US13572612

申请日：2012-08-10

申请人： Giora Arbel ,  Yossi Bar-El

发明人： Giora Arbel ,  Yossi Bar-El

IPC分类号： A61K9/70

CPC分类号： A61K9/7084 ,  A61K9/7023 ,  A61M35/00 ,  A61M2037/0007

摘要： Apparatus and methods are provided including a patch assembly (20) configured to deliver a substance through a subject's skin. A frame (26) surrounds at least in part an open portion of the patch assembly, such that a region of the skin is exposed through the open portion when the frame is placed on the skin. A substance support area (28) is foldably coupled to the frame at a foldable joint (27). A substance delivery area (23) is adapted to be placed in contact with at least a portion of the region of skin, by the substance support area being folded with respect to the frame. A stiffener (29), disposed on the substance support area between the foldable joint and the substance delivery area, is configured to facilitate the placement of the substance delivery area on the portion of the region of skin. Other applications are also described.

摘要翻译： 提供的装置和方法包括配置成将物质输送通过受试者皮肤的补片组件（20）。 框架（26）至少部分地包围贴片组件的开口部分，使得当框架放置在皮肤上时，皮肤的区域通过开口部分露出。 物质支撑区域（28）在可折叠接头（27）处可折叠地联接到框架。 物质输送区域（23）适于通过相对于框架折叠的物质支撑区域与皮肤区域的至少一部分接触放置。 设置在可折叠接头和物质输送区域之间的物质支撑区域上的加强件（29）构造成便于将物质输送区域放置在皮肤区域的该部分上。 还描述了其它应用。