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公开(公告)号:US20090312631A1
公开(公告)日:2009-12-17
申请号:US12485665
申请日:2009-06-16
IPC分类号: A61B6/00
CPC分类号: A61B5/0071 , A61B1/041 , A61B1/043 , A61B5/0084
摘要: Devices, systems and methods for detecting in vivo pathology are provided. An in vivo sensing device comprises a reacting layer with at least one type of binding agent attached thereon, a sensor configured for sensing an optical change occurring on the reacting substrate, and at least one illumination source. In-vivo fluids are in constant contact with the reacting substrate so that in vivo marker indicating pathology may bind to the binding agent attached onto the reacting layer and may be viewed by the sensor.
摘要翻译: 提供用于检测体内病理学的装置,系统和方法。 体内感测装置包括具有附着在其上的至少一种类型的粘合剂的反应层,被配置为感测在反应基底上发生的光学变化的传感器和至少一个照明源。 体内流体与反应底物恒定接触,使体内标记指示病理学可以结合附着在反应层上的结合剂并且可以由传感器观察。
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公开(公告)号:US20050085751A1
公开(公告)日:2005-04-21
申请号:US10936540
申请日:2004-09-09
申请人: Shalom Daskal , Dov Tamarkin , Zvi Nitzan , Nurit Harel , Daniela Mavor , Giora Arbel , Shalom Luski , Noam Emanuel , Dalia Jayes
发明人: Shalom Daskal , Dov Tamarkin , Zvi Nitzan , Nurit Harel , Daniela Mavor , Giora Arbel , Shalom Luski , Noam Emanuel , Dalia Jayes
CPC分类号: A61N1/326 , A61N1/0436 , A61N1/044 , A61N1/0448 , A61N1/325
摘要: The present invention provides a device and kit and method of use thereof for wound treatment of a subject. The device may include an electrically operated patch or other means of delivery of electrical current and a connected moist surface. Optionally, the device may include a composition comprising an active substance useful in wound treatment. Preferably, the means of delivery of electrical current includes a power source and a plurality of electrodes disposed in a suitable conformation on a base substrate layer, which readily facilitates electrical contact with the body area of the subject. Preferably, the kit may include a means of delivery of electrical current and a moist surface provided as separate components. The present invention further provides a thin and flexible device for galvanic treatment to treat wounds with electrical stimulation. Preferably, the device is made using a printing technique.
摘要翻译: 本发明提供了一种用于受试者的伤口治疗的装置和试剂盒及其使用方法。 该装置可以包括电操作的贴片或电流的其它输送装置和连接的潮湿表面。 任选地,装置可以包括包含可用于伤口治疗的活性物质的组合物。 优选地,电流传递装置包括电源和在基底层上以适当构型设置的多个电极,其容易地促进与受试者身体区域的电接触。 优选地,套件可以包括递送电流的装置和作为单独部件提供的潮湿表面。 本发明还提供了一种薄而灵活的电气处理装置,用电刺激来治疗伤口。 优选地,使用印刷技术制造该装置。
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公开(公告)号:US20050038375A1
公开(公告)日:2005-02-17
申请号:US10890297
申请日:2004-07-14
申请人: Zvika Nitzan , Doy Tamarkin , Danlela Mavor , Nurit Harel , Noam Emanuel
发明人: Zvika Nitzan , Doy Tamarkin , Danlela Mavor , Nurit Harel , Noam Emanuel
IPC分类号: A61N1/30
CPC分类号: A61N1/30
摘要: Methods, apparatus, and kits for onychomycosis treatment are presented. In one embodiment, a kit for treatment includes an anti-fungal agent, in a composition, and an electrically powered patch. Exemplary embodiments of the patch include a first electrode, a power source having a first and second terminal, a second electrode coupled to the second terminal of the power source, and a base member supporting the first electrode, the second electrode, and the power source. Embodiments include those where the first and second electrode and power source are printed on the base member. Anti-fungal agents may be unionized while the composition includes an ionizing agent. Home use may be practiced, as embodiments include those in which the voltage or current of the power source cannot be adjusted by a user. Exemplary methods include the selection of a nail or diseased area to which treatment is desired and administering the kit as described.
摘要翻译: 提出了用于甲真菌病治疗的方法,仪器和试剂盒。 在一个实施方案中,用于治疗的试剂盒包括组合物中的抗真菌剂和电动贴剂。 贴片的示例性实施例包括第一电极,具有第一和第二端子的电源,耦合到电源的第二端子的第二电极和支撑第一电极,第二电极和电源的基座部件 。 实施例包括将第一和第二电极和电源印刷在基底构件上的那些。 抗真菌剂可以团聚,而组合物包含电离剂。 可以实施家庭使用,因为实施例包括其中电源的电压或电流不能由用户调整的实施例。 示例性方法包括选择需要治疗的指甲或患病区域,并如所述施用试剂盒。
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公开(公告)号:US07922676B2
公开(公告)日:2011-04-12
申请号:US10936540
申请日:2004-09-09
申请人: Shalom Daskal , Dov Tamarkin , Zvi Nitzan , Nurit Harel , Daniela Mavor , Giora Arbel , Shalom Luski , Noam Emanuel , Dalia Jayes
发明人: Shalom Daskal , Dov Tamarkin , Zvi Nitzan , Nurit Harel , Daniela Mavor , Giora Arbel , Shalom Luski , Noam Emanuel , Dalia Jayes
IPC分类号: A61F5/00
CPC分类号: A61N1/326 , A61N1/0436 , A61N1/044 , A61N1/0448 , A61N1/325
摘要: The present invention provides a device and kit and method of use thereof for wound treatment of a subject. The device may include an electrically operated patch or other means of delivery of electrical current and a connected moist surface. Optionally, the device may include a composition comprising an active substance useful in wound treatment. Preferably, the means of delivery of electrical current includes a power source and a plurality of electrodes disposed in a suitable conformation on a base substrate layer, which readily facilitates electrical contact with the body area of the subject. Preferably, the kit may include a means of delivery of electrical current and a moist surface provided as separate components.The present invention further provides a thin and flexible device for galvanic treatment to treat wounds with electrical stimulation. Preferably, the device is made using a printing technique.
摘要翻译: 本发明提供了一种用于受试者的伤口治疗的装置和试剂盒及其使用方法。 该装置可以包括电操作的贴片或电流的其它输送装置和连接的潮湿表面。 任选地,装置可以包括包含可用于伤口治疗的活性物质的组合物。 优选地,电流传递装置包括电源和在基底层上以适当构型设置的多个电极,其容易地促进与受试者身体区域的电接触。 优选地,套件可以包括递送电流的装置和作为单独部件提供的潮湿表面。 本发明还提供了一种薄而灵活的电气处理装置,用电刺激来治疗伤口。 优选地,使用印刷技术制造该装置。
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公开(公告)号:US08992979B2
公开(公告)日:2015-03-31
申请号:US13383893
申请日:2010-07-14
申请人: Noam Emanuel , Moshe Neuman , Shlomo Barak
发明人: Noam Emanuel , Moshe Neuman , Shlomo Barak
IPC分类号: A61K9/00 , A61P19/08 , A61P35/00 , A61P29/00 , A61P31/04 , A61K31/56 , A61P31/10 , A61K9/16 , A61L24/00 , A61L27/34 , A61L27/54 , A61L31/10 , A61L31/16
CPC分类号: A61K9/1617 , A61K9/1641 , A61K9/1647 , A61K31/65 , A61L24/0015 , A61L27/34 , A61L27/54 , A61L31/10 , A61L31/16 , A61L2300/22 , A61L2300/406 , A61L2300/416 , A61L2300/602
摘要: The present invention provides compositions for extended release of one or more active ingredients, comprising a lipid-saturated matrix formed from a non-biodegradable polymer or a block-co-polymers comprising a non-biodegradable polymer and a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of an active ingredient in the body of a subject in need thereof.
摘要翻译: 本发明提供了用于延长释放一种或多种活性成分的组合物,其包含由不可生物降解的聚合物形成的脂质饱和基质或包含不可生物降解的聚合物和可生物降解的聚合物的嵌段共聚物。 本发明还提供了生产基质组合物的方法和使用该基质组合物来提供活性成分在有需要的受试者体内的受控释放的方法。
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公开(公告)号:US08877242B2
公开(公告)日:2014-11-04
申请号:US13003955
申请日:2009-07-14
申请人: Noam Emanuel , Moshe Neuman , Shlomo Barak
发明人: Noam Emanuel , Moshe Neuman , Shlomo Barak
IPC分类号: A61K9/00 , A61K31/427 , A61K31/192 , A61L27/58 , A61L27/18 , A61L27/54 , A61L31/06 , A61L31/16 , A61P19/08
CPC分类号: A61K47/24 , A61K9/0087 , A61K31/192 , A61K31/427 , A61K31/56 , A61K31/65 , A61K47/22 , A61K47/28 , A61K47/34 , A61K47/42 , A61L27/18 , A61L27/54 , A61L27/58 , A61L31/06 , A61L31/10 , A61L31/16 , A61L2300/204 , A61L2300/222 , A61L2300/404 , A61L2300/406 , A61L2300/41 , A61L2300/412 , A61L2300/602 , A61L2300/606 , A61L2300/802 , A61L2420/04 , C08L67/04
摘要: The present invention provides compositions for extended release of an active ingredient, comprising a lipid-saturated matrix formed from a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of an active ingredient in the body of a subject in need thereof.
摘要翻译: 本发明提供了用于延长释放活性成分的组合物,其包含由可生物降解的聚合物形成的脂质饱和基质。 本发明还提供了生产基质组合物的方法和使用该基质组合物来提供活性成分在有需要的受试者体内的受控释放的方法。
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公开(公告)号:US08795726B2
公开(公告)日:2014-08-05
申请号:US13574040
申请日:2011-01-18
申请人: Noam Emanuel , Yosef Rosenfeld
发明人: Noam Emanuel , Yosef Rosenfeld
IPC分类号: A61K9/26
CPC分类号: A61K9/7007 , A61K9/1075 , A61K31/7088 , A61K48/00 , C12N15/88
摘要: The present invention provides compositions for extended release of a nucleic acid agent, a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of the nucleic acid agent.
摘要翻译: 本发明提供了用于延长释放核酸试剂,可生物降解的聚合物的组合物。 本发明还提供了生产基质组合物的方法和使用该基质组合物来提供核酸试剂受控释放的方法。
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公开(公告)号:US08515507B2
公开(公告)日:2013-08-20
申请号:US12485665
申请日:2009-06-16
IPC分类号: A61B5/1455
CPC分类号: A61B5/0071 , A61B1/041 , A61B1/043 , A61B5/0084
摘要: Devices, systems and methods for detecting in vivo pathology are provided. An in vivo sensing device comprises a reacting layer with at least one type of binding agent attached thereon, a sensor configured for sensing an optical change occurring on the reacting substrate, and at least one illumination source. In-vivo fluids are in constant contact with the reacting substrate so that in vivo marker indicating pathology may bind to the binding agent attached onto the reacting layer and may be viewed by the sensor.
摘要翻译: 提供用于检测体内病理学的装置,系统和方法。 体内感测装置包括具有附着在其上的至少一种类型的粘合剂的反应层,被配置为感测在反应基底上发生的光学变化的传感器和至少一个照明源。 体内流体与反应底物恒定接触,使体内标记指示病理学可以结合附着在反应层上的结合剂并且可以由传感器观察。
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公开(公告)号:US20120294944A1
公开(公告)日:2012-11-22
申请号:US13574040
申请日:2011-01-18
申请人: Noam Emanuel , Yosef Rosenfeld
发明人: Noam Emanuel , Yosef Rosenfeld
IPC分类号: A61K31/7088 , A61K48/00 , A61K31/7105 , A61K9/00 , A61K31/713 , A61K31/711
CPC分类号: A61K9/7007 , A61K9/1075 , A61K31/7088 , A61K48/00 , C12N15/88
摘要: The present invention provides compositions for extended release of a nucleic acid agent, a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of the nucleic acid agent.
摘要翻译: 本发明提供了用于延长释放核酸试剂,可生物降解的聚合物的组合物。 本发明还提供了生产基质组合物的方法和使用该基质组合物来提供核酸试剂受控释放的方法。
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公开(公告)号:US20110117197A1
公开(公告)日:2011-05-19
申请号:US13003955
申请日:2009-07-14
申请人: Noam Emanuel , Moshe Neuman , Shlomo Barak
发明人: Noam Emanuel , Moshe Neuman , Shlomo Barak
IPC分类号: A61K9/00 , A61K31/427 , A61K31/192 , A61K31/65 , A61P31/00 , A61P31/04 , A61P31/10 , A61P19/08 , A61P35/00
CPC分类号: A61K47/24 , A61K9/0087 , A61K31/192 , A61K31/427 , A61K31/56 , A61K31/65 , A61K47/22 , A61K47/28 , A61K47/34 , A61K47/42 , A61L27/18 , A61L27/54 , A61L27/58 , A61L31/06 , A61L31/10 , A61L31/16 , A61L2300/204 , A61L2300/222 , A61L2300/404 , A61L2300/406 , A61L2300/41 , A61L2300/412 , A61L2300/602 , A61L2300/606 , A61L2300/802 , A61L2420/04 , C08L67/04
摘要: The present invention provides compositions for extended release of an active ingredient, comprising a lipid-saturated matrix formed from a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of an active ingredient in the body of a subject in need thereof.
摘要翻译: 本发明提供了用于延长释放活性成分的组合物,其包含由可生物降解的聚合物形成的脂质饱和基质。 本发明还提供了生产基质组合物的方法和使用该基质组合物来提供活性成分在有需要的受试者体内的受控释放的方法。
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