公开(公告)号：US20110202016A1

公开(公告)日：2011-08-18

申请号：US12862362

申请日：2010-08-24

Applicant: Gregory Zugates ,  Upma Sharma ,  Irina Gitlin ,  Jeffrey D. Carbeck ,  Amar Kendale ,  Danny Concagh

Inventor： Gregory Zugates ,  Upma Sharma ,  Irina Gitlin ,  Jeffrey D. Carbeck ,  Amar Kendale ,  Danny Concagh

IPC: A61M35/00 ,  A61L15/22

CPC classification number: A61L24/043 ,  A61L24/0036 ,  A61L2400/06 ,  A61M31/002 ,  C08L75/04 ,  C08L71/02

Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).

Abstract translation: 通常描述与聚合物泡沫有关的系统和方法。 一些实施方案涉及用于制备聚合物泡沫的组合物和方法，以及使用聚合物泡沫体的方法。 聚合物泡沫可以施加到体腔并且与例如组织，损伤的组织，内部器官等接触。在一些实施方案中，聚合物泡沫可以在体腔内形成（即，原位泡沫形成 ）。 此外，发泡聚合物可能能够在体腔的内表面上施加压力，并且能够防止或限制体液（例如血液等）的移动。

公开(公告)号：US20170056436A1

公开(公告)日：2017-03-02

申请号：US15254552

申请日：2016-09-01

Applicant: Gregory Zugates ,  Chetan Khatri ,  Joseph Lomakin ,  Craig Wiltsey

Inventor： Gregory Zugates ,  Chetan Khatri ,  Joseph Lomakin ,  Craig Wiltsey

IPC: A61K31/80 ,  A61K49/00 ,  C08G77/388 ,  A61F2/07 ,  A61M5/00 ,  A61M5/178 ,  A61J1/14 ,  A61B17/12 ,  A61K9/00 ,  C08L83/08

CPC classification number: A61K31/80 ,  A61B17/12118 ,  A61B17/12186 ,  A61B17/12195 ,  A61B2090/064 ,  A61F2/07 ,  A61J1/1468 ,  A61K9/0019 ,  A61K49/0002 ,  A61M5/007 ,  A61M5/178 ,  C08G77/388 ,  C08L83/08

Abstract: The present disclosure is directed to moisture curing formulations as well as articles, devices, systems, kits and methods based on the same.

Abstract translation: 本公开涉及湿固化配方以及基于其的制品，装置，系统，试剂盒和方法。

公开(公告)号：US20120265287A1

公开(公告)日：2012-10-18

申请号：US13532013

申请日：2012-06-25

Applicant: Upma Sharma ,  Gregory Zugates ,  Rany Busold ,  Toby Freyman

Inventor： Upma Sharma ,  Gregory Zugates ,  Rany Busold ,  Toby Freyman

IPC: A61F2/82 ,  A61F2/84 ,  A61F2/06

Abstract: Systems, methods and kits relating to in-situ forming polymer foams for the treatment of aneurysms are disclosed. The systems include an insertable medical device and an in-situ forming foam that is formed from a polymer that reacts in an aqueous environment. When used to treat an aneurysm, the foam is placed into contact with at least a portion of an exterior surface of the medical device and/or the tissue surface of the aneurysm.

Abstract translation: 公开了与用于治疗动脉瘤的原位形成聚合物泡沫有关的系统，方法和试剂盒。 该系统包括可插入的医疗装置和由在水性环境中反应的聚合物形成的原位成形泡沫。 当用于治疗动脉瘤时，将泡沫放置成与医疗装置的外表面的至少一部分和/或动脉瘤的组织表面接触。

公开(公告)号：US10420862B2

公开(公告)日：2019-09-24

申请号：US13532013

申请日：2012-06-25

Applicant: Upma Sharma ,  Gregory Zugates ,  Rany Busold ,  Toby Freyman

Inventor： Upma Sharma ,  Gregory Zugates ,  Rany Busold ,  Toby Freyman

IPC: A61F2/82 ,  A61L31/14 ,  A61L31/06 ,  A61L31/18 ,  A61M25/00

Abstract: Systems, methods and kits relating to in-situ forming polymer foams for the treatment of aneurysms are disclosed. The systems include an insertable medical device and an in-situ forming foam that is formed from a polymer that reacts in an aqueous environment. When used to treat an aneurysm, the foam is placed into contact with at least a portion of an exterior surface of the medical device and/or the tissue surface of the aneurysm.