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公开(公告)号：US20160296723A1
公开(公告)日：2016-10-13
申请号：US15093264
申请日：2016-04-07
Applicant: Rany Busold , Jeffrey V. Groom, II , Jennifer Mortensen , Xuri R. Yan , Stephanie Webber
Inventor： Rany Busold , Jeffrey V. Groom, II , Jennifer Mortensen , Xuri R. Yan , Stephanie Webber
CPC classification number: A61M25/0074 , A61B17/00491 , A61B17/12113 , A61B17/12181 , A61B17/12186 , A61B17/1219 , A61B17/12195 , A61B2017/00402 , A61B2017/00411 , A61B2017/00495 , A61M25/0026 , A61M25/0068 , A61M2025/0024 , A61M2025/0073
Abstract: Dual-lumen catheters for actively mixing two or more fluid components such that they react to form a more viscous pre-polymer formulation at or near the distal tip of the catheter are describe herein. The mixing dynamics within the dual-lumen catheter may be varied depending on the relative viscosity of each individual fluid component, as well as the viscosity of the resulting pre-polymer formulation.
Abstract translation: 本文描述了用于主动混合两种或更多种流体组分以使得它们在导管的远侧末端处或其附近形成更粘稠的预聚物制剂的双腔导管。 双腔导管内的混合动力学可以根据每个单独流体组分的相对粘度以及所得预聚物制剂的粘度而变化。
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公开(公告)号：US20160081830A1
公开(公告)日：2016-03-24
申请号：US14953542
申请日：2015-11-30
Applicant: Nareak Douk , Rany Busold , Lee Core , Kicherl Ho , My Le , Timothy Walter Robinson , Sarah Kostanski , Benedict Shia , Jerry Brightbill
Inventor： Nareak Douk , Rany Busold , Lee Core , Kicherl Ho , My Le , Timothy Walter Robinson , Sarah Kostanski , Benedict Shia , Jerry Brightbill
CPC classification number: A61F2/966 , A61F2/86 , A61F2/90 , A61F2002/826 , A61F2002/9505 , A61F2002/9522 , A61F2002/9665 , A61F2230/0054
Abstract: Delivery systems for a polymeric tubular implant, kits that include such delivery systems, and methods of treating patients by implanting tubular implants using the delivery systems. The delivery systems include an inner shaft, an expandable member slidably disposed about the inner shaft and configured to receive the tubular implant, and a tubular outer shaft disposed about the inner shaft.
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公开(公告)号：US20160051264A1
公开(公告)日：2016-02-25
申请号：US14728393
申请日：2015-06-02
Applicant: Toby Freyman , Joseph Lomakin , John Marini , Jennifer Mortensen , Adam Rago , Rany Busold , Upma Sharma , Gregory T. Zugates
Inventor： Toby Freyman , Joseph Lomakin , John Marini , Jennifer Mortensen , Adam Rago , Rany Busold , Upma Sharma , Gregory T. Zugates
CPC classification number: A61B17/12181 , A61B17/12113 , A61B17/12118 , A61B17/1214 , A61B2017/1205 , A61F2/07 , A61F2002/065 , A61F2002/077 , A61F2210/0085 , A61J1/2093 , A61L24/0036 , A61L24/0089 , A61L24/046 , A61L31/06 , A61L31/128 , A61L31/146 , A61L2300/60 , A61L2400/06 , A61M37/00 , C08L67/04 , C08L83/04
Abstract: Systems, methods and kits relating to in-situ forming polymer foams for the treatment of aneurysms or fluid filled spaces are disclosed. The systems include an insertable medical device and an in-situ forming foam of lava like materials with a fast forming outer skin and a slower hardening interior that is formed from a one-, two- or multi-part formulation. When used to treat an aneurysm, the foam is placed into contact with at least a portion of an exterior surface of the medical device and/or the tissue surface of the aneurysm.
Abstract translation: 公开了与原位形成聚合物泡沫相关的用于治疗动脉瘤或填充液体的空间的系统，方法和试剂盒。 这些系统包括可插入的医疗装置和具有快速成形外皮的熔岩状材料的原位成形泡沫体，以及由一部分，两部分或多部分制剂形成的较慢的硬化内部。 当用于治疗动脉瘤时，将泡沫放置成与医疗装置的外表面的至少一部分和/或动脉瘤的组织表面接触。
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公开(公告)号：US09198783B2
公开(公告)日：2015-12-01
申请号：US13606962
申请日：2012-09-07
Applicant: Nareak Douk , Rany Busold , Lee Core , Kicherl Ho , My Le , Timothy Walter Robinson , Sarah Kostanski , Benedict Shia , Jerry Brightbill
Inventor： Nareak Douk , Rany Busold , Lee Core , Kicherl Ho , My Le , Timothy Walter Robinson , Sarah Kostanski , Benedict Shia , Jerry Brightbill
CPC classification number: A61F2/966 , A61F2/86 , A61F2/90 , A61F2002/826 , A61F2002/9505 , A61F2002/9522 , A61F2002/9665 , A61F2230/0054
Abstract: Delivery systems for a polymeric tubular implant, kits that include such delivery systems, and methods of treating patients by implanting tubular implants using the delivery systems. The delivery systems include an inner shaft, an expandable member slidably disposed about the inner shaft and configured to receive the tubular implant, and a tubular outer shaft disposed about the inner shaft.
Abstract translation: 用于聚合物管状植入物的递送系统，包括这种递送系统的试剂盒以及通过使用递送系统植入管状植入物来治疗患者的方法。 输送系统包括内轴，可滑动地设置在内轴周围并构造成容纳管状植入物的可扩张构件以及围绕内轴设置的管状外轴。
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5.发明申请公开(公告)号：US20140228745A1
公开(公告)日：2014-08-14
申请号：US14211469
申请日：2014-03-14
Applicant: Upma Sharma , Rany Busold , Adam Rago , Gregory T. Zugates , Toby Freyman , Lisette Manrique Miller
Inventor： Upma Sharma , Rany Busold , Adam Rago , Gregory T. Zugates , Toby Freyman , Lisette Manrique Miller
CPC classification number: A61B17/00491 , A61B2017/00398 , A61B2017/00495 , A61B2017/00544 , A61B2017/00548 , A61B2017/8838 , A61C9/0026 , A61M5/1409 , A61M5/1452 , A61M5/16804 , A61M5/19 , A61M13/003 , A61M2205/103 , B01F3/04453 , B01F5/0602 , B01F5/0604 , B01F7/00558 , B01F7/00583 , B01F13/0023 , B01F15/00253 , B01F15/00525 , B01F15/0279 , B05B7/0037 , B05B7/2421 , B05B7/2472 , B05C17/00553 , B65D81/325
Abstract: Delivery systems for in situ forming foam formulations are provided. The devices may include various actuation mechanisms and may entrain air into fluid formulation components in a variety of ways, including mixing with air and the addition of compressed gas.
Abstract translation: 提供了用于原位形成泡沫配方的输送系统。 装置可以包括各种致动机构，并且可以以各种方式将空气夹带到流体配方部件中，包括与空气混合和加入压缩气体。
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Patent Agency Ranking
公开(公告)号：US20120107439A1
公开(公告)日：2012-05-03
申请号：US13209020
申请日：2011-08-12
Applicant: Upma Sharma , Irina Gitlin , Gregory T. Zugates , Adam Rago , Parisa Zamiri , Rany Busold , Robert J. Caulkins , Toby Freyman , Quynh P. Pham , Changcheng You , Jeffrey D. Carbeck
Inventor： Upma Sharma , Irina Gitlin , Gregory T. Zugates , Adam Rago , Parisa Zamiri , Rany Busold , Robert J. Caulkins , Toby Freyman , Quynh P. Pham , Changcheng You , Jeffrey D. Carbeck
IPC: B29C44/04
CPC classification number: A61L31/06 , A61B17/12031 , A61B17/12163 , A61B17/12186 , A61B2017/12004 , A61J1/2093 , A61L27/18 , A61L27/56 , A61L27/58 , A61L31/141 , A61L31/146 , A61L31/148 , A61L2400/04 , A61L2400/06 , A61L2400/18 , A61M37/00 , C08L63/00 , C08L67/04
Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
Abstract translation: 通常描述与聚合物泡沫有关的系统和方法。 一些实施方案涉及用于制备聚合物泡沫的组合物和方法，以及使用聚合物泡沫体的方法。 聚合物泡沫可以施加到体腔并且与例如组织，损伤的组织，内部器官等接触。在一些实施方案中，聚合物泡沫可以在体腔内形成（即，原位泡沫形成 ）。 此外，发泡聚合物可能能够在体腔的内表面上施加压力，并且能够防止或限制体液（例如血液等）的移动。
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公开(公告)号：US08137396B2
公开(公告)日：2012-03-20
申请号：US12783261
申请日：2010-05-19
Applicant: Rany Busold , Chang cheng You , Daniel Concagh , Lee Core , Kicherl Ho , Maria Palasis , Upma Sharma , Greg Zugates
Inventor： Rany Busold , Chang cheng You , Daniel Concagh , Lee Core , Kicherl Ho , Maria Palasis , Upma Sharma , Greg Zugates
IPC: A61F2/06
CPC classification number: A61F2/86 , A61F2/90 , A61F2/95 , A61F2230/0054 , A61L31/06 , A61L31/10 , A61L31/14 , A61L31/16 , D04C1/06 , D10B2403/0112 , D10B2509/06 , C08L67/04
Abstract: Disclosed is a self-expanding medical implant for placement within a lumen of a patient. The implant comprises a woven or non-woven structure having a substantially tubular configuration, and is designed to be low-profile such that it is deliverable with a small diameter catheter. The implant has a high recoverability and desired mechanical properties.
Abstract translation: 公开了一种用于放置在患者的内腔内的自扩张医用植入物。 植入物包括具有基本上管状构造的织造或非织造结构，并且被设计为低轮廓，使得其可以用小直径导管递送。 植入物具有高回收性和所需的机械性能。
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公开(公告)号：US09278016B2
公开(公告)日：2016-03-08
申请号：US13032281
申请日：2011-02-22
Applicant: Rany Busold , Changcheng You , Daniel Concagh , Lee Core , Kicherl Ho , Maria Palasis , Upma Sharma , Greg Zugates
Inventor： Rany Busold , Changcheng You , Daniel Concagh , Lee Core , Kicherl Ho , Maria Palasis , Upma Sharma , Greg Zugates
CPC classification number: A61F2/86 , A61F2/90 , A61F2/95 , A61F2230/0054 , A61L31/06 , A61L31/10 , A61L31/14 , A61L31/16 , D04C1/06 , D10B2403/0112 , D10B2509/06 , C08L67/04
Abstract: Disclosed is a self-expanding medical implant for placement within a lumen of a patient. The implant comprises a woven or non-woven structure having a substantially tubular configuration, and is designed to be low-profile such that it is deliverable with a small diameter catheter. The implant has a high recoverability and desired mechanical properties.
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公开(公告)号：US20150224235A1
公开(公告)日：2015-08-13
申请号：US14492393
申请日：2014-09-22
Applicant: Upma Sharma , Irina Gitlin , Gregory T. Zugates , Adam Rago , Parisa Zamiri , Rany Busold , Toby Freyman , Robert J. Caulkins , Quynh P. Pham , Changchen You , Jeffrey D. Carbeck
Inventor： Upma Sharma , Irina Gitlin , Gregory T. Zugates , Adam Rago , Parisa Zamiri , Rany Busold , Toby Freyman , Robert J. Caulkins , Quynh P. Pham , Changchen You , Jeffrey D. Carbeck
CPC classification number: A61L31/06 , A61B17/12031 , A61B17/12163 , A61B17/12186 , A61B2017/12004 , A61J1/2093 , A61L27/18 , A61L27/56 , A61L27/58 , A61L31/141 , A61L31/146 , A61L31/148 , A61L2400/04 , A61L2400/06 , A61L2400/18 , A61M37/00 , C08L63/00 , C08L67/04
Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
Abstract translation: 通常描述与聚合物泡沫有关的系统和方法。 一些实施方案涉及用于制备聚合物泡沫的组合物和方法，以及使用聚合物泡沫体的方法。 聚合物泡沫可以施加到体腔并且与例如组织，损伤的组织，内部器官等接触。在一些实施方案中，聚合物泡沫可以在体腔内形成（即，原位泡沫形成 ）。 此外，发泡聚合物可能能够在体腔的内表面上施加压力，并且能够防止或限制体液（例如血液等）的移动。
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公开(公告)号：US20140316367A1
公开(公告)日：2014-10-23
申请号：US14215988
申请日：2014-03-17
Applicant: Gregory T. Zugates , Adam Rago , Toby Freyman , Upma Sharma , Rany Busold , John Caulkins , Parisa Zamiri , Jennifer Mortensen , Meghan McGill , Daniel K. Bonner
Inventor： Gregory T. Zugates , Adam Rago , Toby Freyman , Upma Sharma , Rany Busold , John Caulkins , Parisa Zamiri , Jennifer Mortensen , Meghan McGill , Daniel K. Bonner
CPC classification number: A61L24/0015 , A61L24/0036 , A61L24/046 , A61L27/14 , A61L27/56 , A61L31/04 , A61L31/146 , A61L2300/418 , A61L2400/04 , A61L2430/22 , C08L75/04
Abstract: The present invention relates generally to systems and methods and systems for generating polymer foams within body cavities to locate and/or control bleeding. The present invention further relates to methods and systems for generating polymer foams within non-compressible wounds to control or stop bleeding. The present invention further relates to the use of foams and gels for medical and cosmetic purposes.
Abstract translation: 本发明一般涉及用于在体腔内产生聚合物泡沫以定位和/或控制出血的系统和方法和系统。 本发明还涉及用于在不可压缩伤口内产生聚合物泡沫以控制或止血的方法和系统。 本发明还涉及泡沫和凝胶用于医疗和化妆用途的用途。
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