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    Medical Material and Process for Producing the Same
    1.
    发明申请
    Medical Material and Process for Producing the Same 审中-公开
    医疗材料及其生产工艺

    公开(公告)号：US20070254013A1

    公开(公告)日：2007-11-01

    申请号：US10588309

    申请日：2005-02-01

    申请人： Tetsushi Taguchi ,  Hisatoshi Kobayashi ,  Junzo Tanaka ,  Kazuo Tsubota ,  Naoshi Shinozaki ,  Shigeto Shimmura ,  Hideyuki Miyashita

    发明人： Tetsushi Taguchi ,  Hisatoshi Kobayashi ,  Junzo Tanaka ,  Kazuo Tsubota ,  Naoshi Shinozaki ,  Shigeto Shimmura ,  Hideyuki Miyashita

    IPC分类号： A61F2/14

    CPC分类号： A61L27/3804 ,  A61L27/3604 ,  A61L27/3641 ,  A61L27/3687 ,  A61L27/3839 ,  A61L2430/16

    摘要： [Object] A medical material that improves therapeutic effects in epithelial cells such as keratoconjunctival epithelial cells with the use of an amnion, and a process for producing the same are provided. [Solving Means] A medical material includes an amnion, which is a placental tissue, a polymer film bonded to one surface of the amnion and crosslinked, and cells adhered to the other surface of the amnion. A process for producing the medical material includes the steps of preparing an amnion from which the spongy layer is removed, bonding a biocompatible polymer film to one surface of the amnion followed by crosslinking, adhering epithelial stem cells to the other surface of the amnion, and proliferating epithelial cells from the epithelial stem cells on the surface of the amnion.

    摘要翻译： 提供了一种使用羊膜改善上皮细胞如角膜结膜上皮细胞治疗效果的医疗材料及其制造方法。 [解决方案]药物材料包括羊膜，羊膜组织，与羊膜的一个表面结合并交联的聚合物膜，以及附着在羊膜的另一表面的细胞。 制造医疗材料的方法包括以下步骤：制备从其中除去海绵层的羊膜，将生物相容性聚合物膜粘合到羊膜的一个表面，然后交联，将上皮干细胞粘附到羊膜的另一个表面，以及 从羊膜表面的上皮干细胞增殖上皮细胞。