Refrigerator oil composition
    2.
    发明授权
    Refrigerator oil composition 失效
    冰箱油组成

    公开(公告)号:US4800013A

    公开(公告)日:1989-01-24

    申请号:US50501

    申请日:1987-05-13

    摘要: The present invention relates to a refrigerator oil composition which comprises 70 to 98 wt % of a paraffin base oil having a pour point of not more than -35.degree. C., a sulfur content of not more than 50 ppm (parts per million), and a kinematic viscosity at 40.degree. C. of 5 to 500 cSt (centistrokes) and 30 to 2 wt % of a naphthene base oil having a pour point of not more than -35.degree. C., a sulfur content of 0.05 to 1 wt % and a kinematic viscosity at 40.degree. C. of 5 to 500 cSt, and in which the sulfur content is 0.01 to 0.10 wt %.The refrigerator oil composition of the present invention effectively prevents the formation of valve sludge. The refrigerator oil composition of the present invention is also excellent in anti-wear properties. Furthermore the refrigerator oil composition of the present invention is excellent in stability and baking resistance in the condition that is in contact with the refrigerant (Furon) and further is excellent in low temperature solubility. Moreover the refrigerator oil machine oil composition of the present invention contains as a main component a paraffin base oil which is steadily available.

    摘要翻译: 本发明涉及一种冷冻机油组合物,其包含70〜98重量%的倾点不大于-35℃的石蜡基油,硫含量不超过50ppm(百万分之一), 在40℃下的运动粘度为5至500cSt(中心密度)和30至2重量%的倾点不大于-35℃的环烷烃基油,硫含量为0.05-1重量% %,40℃下的运动粘度为5〜500cSt,硫含量为0.01〜0.10重量%。 本发明的冷冻机油组合物有效地防止了阀门污泥的形成。 本发明的冷冻机油组合物的耐磨损性也优异。 此外,本发明的冷冻机油组合物在与制冷剂(Furon)接触的状态下的稳定性和耐烘烤性优异,并且还具有优异的低温溶解性。 此外,本发明的冷冻机油机油组合物含有稳定可用的石蜡基油作为主要成分。

    Method for judging effectiveness of drug having protease inhibitory activity
    3.
    发明授权
    Method for judging effectiveness of drug having protease inhibitory activity 有权
    评估具有蛋白酶抑制活性的药物有效性的方法

    公开(公告)号:US06413734B1

    公开(公告)日:2002-07-02

    申请号:US09641349

    申请日:2000-08-18

    IPC分类号: C12Q137

    摘要: A method for judging effectiveness of a drug having protease inhibitory activity, which comprises the steps of: (1) bringing a biosample isolated or collected from a patient with a disease in which participation of a protease is suspected into contact with a thin membrane containing a protease substrate and formed on a surface of a support; (2) detecting a trace of digestion formed on the thin membrane by action of a protease; and (3) judging that a drug having protease inhibitory activity is effective for the patient when a trace of digestion is formed on the thin membrane. The method enables accurate judgment as to whether or not a drug having protease inhibitory activity is effective for a patient with a disease in which participation of a protease is suspected such as rheumatoid arthritis and cancer before administration of the drug.

    摘要翻译: 一种用于判断具有蛋白酶抑制活性的药物的有效性的方法,其包括以下步骤:(1)将患有蛋白酶参与的患者分离或收集的生物样品与含有蛋白酶抑制活性的薄膜接触的疾病 蛋白酶底物并形成在支撑体的表面上; (2)通过蛋白酶的作用检测在薄膜上形成的消化痕迹; 和(3)当在薄膜上形成消化痕迹时,判断具有蛋白酶抑制活性的药物对患者有效。 该方法能够准确判断具有蛋白酶抑制活性的药物是否有疑似患有蛋白酶参与的疾病的患者,例如类风湿性关节炎和药物给药前的癌症。

    Pharmaceutical composition for treating fatty liver or hepatic disease
    4.
    发明申请
    Pharmaceutical composition for treating fatty liver or hepatic disease 审中-公开
    用于治疗脂肪肝或肝病的药物组合物

    公开(公告)号:US20070066681A1

    公开(公告)日:2007-03-22

    申请号:US10573036

    申请日:2004-09-22

    IPC分类号: A61K31/343

    CPC分类号: C07D307/79 A61K31/343

    摘要: A pharmaceutical composition, and a method using the composition, for prevention and/or treatment of fatty liver or hepatic disease, the composition comprising, as an active ingredient, a compound of the formula (1): where R1 is a hydrogen atom, an acyl group, or an arylalkoxycarbonyl group; and R2 and R3 are each independently a substituted or unsubstituted alkyl group, a substituted or unsubstituted alkenyl group, or a substituted or unsubstituted alkynyl group, or R2 and R3 may combine to form a cycloalkyl group.

    摘要翻译: 一种药物组合物和使用该组合物的方法,用于预防和/或治疗脂肪肝或肝脏疾病,所述组合物包含作为活性成分的式(1)化合物:其中R 1, SUP>是氢原子,酰基或芳基烷氧基羰基; R 2和R 3各自独立地为取代或未取代的烷基,取代或未取代的烯基或取代或未取代的炔基, 2和R 3可以结合形成环烷基。