公开(公告)号：US07482322B2

公开(公告)日：2009-01-27

申请号：US10573262

申请日：2004-10-28

申请人： Hisashi Koga ,  Osamu Ohara ,  Haruhiko Koseki ,  Mitsuhiro Okada ,  Akiyoshi Uemura ,  Hiroki Arakawa ,  Mitsuhiro Tada

发明人： Hisashi Koga ,  Osamu Ohara ,  Haruhiko Koseki ,  Mitsuhiro Okada ,  Akiyoshi Uemura ,  Hiroki Arakawa ,  Mitsuhiro Tada

IPC分类号： A61K38/16 ,  A61K38/00 ,  C07K14/435 ,  C07K14/00

CPC分类号： C07K14/705 ,  A61K38/00

摘要： The present invention is directed to a novel plexin family like DNA, a gene containing the DNA, novel polypeptide encoded by the DNA, a recombinant protein containing the polypeptide or heterologous polypeptide sequences, antibodies which bind to the polypeptides, methods for producing the polypeptides of the present invention. Conditions that can be diagnosed, screened, prevented, or treated by the compositions herein include prophylactic, angiogenesis and conservation of functions in various organs, angiogenesis at the time of tumor and regeneration of various organs, proliferation, differentiation and preservation of function of the cells in various organs, aging, and dysfunction of the present invention.

摘要翻译： 本发明涉及一种新型的plexin家族如DNA，含有该DNA的基因，由该DNA编码的新型多肽，含有该多肽或异源多肽序列的重组蛋白，与该多肽结合的抗体，产生多肽的多肽的方法 本发明。 可以通过本文组合物诊断，筛选，预防或治疗的病症包括各种器官的功能的预防，血管生成和保护，肿瘤时的血管发生和各种器官的再生，细胞的功能的增殖，分化和保存 在本发明的各种器官，衰老和功能障碍中。

公开(公告)号：US20070212365A1

公开(公告)日：2007-09-13

申请号：US10573262

申请日：2004-10-28

申请人： Hisashi Koga ,  Osamu Ohara ,  Haruhiko Koseki ,  Mitsuhiro Okada ,  Akiyoshi Uemura ,  Hiroki Arakawa ,  Mitsuhiro Tada

发明人： Hisashi Koga ,  Osamu Ohara ,  Haruhiko Koseki ,  Mitsuhiro Okada ,  Akiyoshi Uemura ,  Hiroki Arakawa ,  Mitsuhiro Tada

IPC分类号： A61K39/00 ,  G01N33/574 ,  C07H21/04 ,  C12P21/06 ,  C12N5/06 ,  C07K14/82

CPC分类号： C07K14/705 ,  A61K38/00

摘要： The object of the invention is to provide novel DNA, a gene containing the DNA, novel polypeptide encoded by the DNA, a recombinant protein containing the polypeptide, or an antibody against the polypeptide, which is useful for development and screening of prophylactic, therapeutic and diagnostic drug for angiogenesis and conservation of functions in various organs, angiogenesis at the time of tumor and regeneration of various organs, proliferation, differentiation and preservation of function of the cells in various organs, aging, and dysfunction. Means to Solve the Problem A DNA comprising a base sequence encoding one of the following polypeptide (a) or (b): (a) a polypeptide comprising the full length or a part of an amino acid sequence which is the same or substantially the same as an amino acid sequence represented by SEQ ID NO:1, SEQ ID NO:15 or SEQ ID NO:18, and (b) a polypeptide comprising an amino acid sequence derived from an amino acid sequence represented by SEQ ID NO:1, SEQ ID NO:15 or SEQ ID NO:18 by deletion, substitution or addition of a part of the amino acids and having a biological activity substantially equivalent to the polypeptide (a).

摘要翻译： 本发明的目的是提供新的DNA，含有DNA的基因，由DNA编码的新型多肽，含有多肽的重组蛋白或抗多肽的抗体，其可用于开发和筛选预防性治疗和 用于血管发生的诊断药物和各种器官功能的保存，肿瘤时的血管发生和各种器官的再生，增殖，分化和保存各种器官，衰老和功能障碍中的细胞的功能。 解决问题的方法包含编码以下多肽（a）或（b）之一的碱基序列的DNA：（a）包含相同或基本相同的氨基酸序列的全长或部分的多肽 作为由SEQ ID NO：1，SEQ ID NO：15或SEQ ID NO：18表示的氨基酸序列，和（b）包含源自SEQ ID NO：1所示氨基酸序列的氨基酸序列的多肽， SEQ ID NO：15或SEQ ID NO：18，通过缺失，取代或添加一部分氨基酸并且具有与多肽（a）基本相同的生物活性。

公开(公告)号：US06654385B1

公开(公告)日：2003-11-25

申请号：US09362169

申请日：1999-07-27

申请人： Hiromi Odaka ,  Sumie Morita ,  Shigeru Sekine ,  Eiji Ishioka ,  Hisashi Koga

发明人： Hiromi Odaka ,  Sumie Morita ,  Shigeru Sekine ,  Eiji Ishioka ,  Hisashi Koga

IPC分类号： H04J316

CPC分类号： H04L12/403 ,  H04L1/16 ,  H04L12/40013 ,  H04L12/46

摘要： A message division communication method and system are disclosed for a communication system comprising a host, an intermediate device connected to the host through a high-speed bus and a remote device connected to the intermediate device or the host through a low-speed bus. A message is transmitted in such a manner that the host designates and notifies the remote device of a maximum message length determined in a way corresponding to the transmission rate of the low-speed bus and divides the message into division messages each not exceeding the maximum message length thereby to transmit and receive the division messages between the host and the remote device. Even with a communication system in which low-speed and high-speed buses coexist, a message can be transmitted and received by a common communication control scheme.

摘要翻译： 公开了一种用于通信系统的消息分割通信方法和系统，所述通信系统包括主机，通过高速总线连接到主机的中间设备和通过低速总线连接到中间设备或主机的远程设备。 以如下方式发送消息：主机以与低速总线的传输速率对应的方式确定的最大消息长度来指定和通知远程设备，并将该消息划分为不超过最大消息的分割消息 长度，从而在主机和远程设备之间发送和接收除法消息。 即使使用低速和高速总线共存的通信系统，也可以通过公共通信控制方案发送和接收消息。

公开(公告)号：US06556675B2

公开(公告)日：2003-04-29

申请号：US09081367

申请日：2002-06-27

申请人： Hisashi Koga

发明人： Hisashi Koga

IPC分类号： H04M100

CPC分类号： H04Q1/028 ,  H04M3/005 ,  H04M3/2272 ,  H04M2207/08 ,  H04Q2201/10

摘要： In a subscriber line control device connected to a plurality of subscriber circuits, there is a memory circuit for recording signal data indicating the states of subscriber lines, and hardware for displaying flags denoting changes in the signal data indicating the states of the subscriber lines, as well as firmware for monitoring periodically the flags displayed by the hardware.

摘要翻译： 在连接到多个用户电路的用户线路控制装置中，存在用于记录指示用户线路的状态的信号数据的存储电路，以及表示表示用户线路的状态的信号数据的变化的标志的硬件，如 以及用于定期监视硬件显示的标志的固件。

公开(公告)号：US5963541A

公开(公告)日：1999-10-05

申请号：US552485

申请日：1995-11-09

申请人： Hisashi Koga ,  Takashi Sugino ,  Toshiaki Ohishi

发明人： Hisashi Koga ,  Takashi Sugino ,  Toshiaki Ohishi

IPC分类号： H04Q3/00 ,  H04L12/801 ,  H04L12/803 ,  H04L12/819 ,  H04L12/861 ,  H04L12/911 ,  H04Q11/04 ,  H04J3/14

CPC分类号： H04Q11/0478 ,  H04L2012/5618 ,  H04L2012/5632 ,  H04L2012/5636 ,  H04L2012/567 ,  H04L2012/5678

摘要： A time division allocating unit distributes a plurality of data links at a plurality of time division timings into which a predetermined period is divided. A communicable remaining data supplying process executing unit executes a supplying process of the remaining data for a data link, which allocated by the time division allocating unit at each time division timing, only when a communicable data supplying process commanding unit commands an execution of the supplying process of the communicable remaining data for the allocated data link.

摘要翻译： 时分分配单元在分割预定时段的多个时分定时分配多个数据链路。 可通信的剩余数据提供处理执行单元仅在通信数据提供处理指令单元命令执行供应时执行由时间分配单元在每个分时定时分配的数据链路的剩余数据的提供处理 处理分配的数据链路的可传送的剩余数据。

公开(公告)号：US20090215170A1

公开(公告)日：2009-08-27

申请号：US12318086

申请日：2008-12-22

申请人： Hisashi Koga ,  Osamu Ohara ,  Haruhiko Koseki ,  Mitsuhiro Okada ,  Akiyoshi Uemura ,  Hiroki Arakawa ,  Mitsuhiro Tada

发明人： Hisashi Koga ,  Osamu Ohara ,  Haruhiko Koseki ,  Mitsuhiro Okada ,  Akiyoshi Uemura ,  Hiroki Arakawa ,  Mitsuhiro Tada

IPC分类号： C12N5/10 ,  C07H21/04 ,  C12N15/63

CPC分类号： C07K14/705 ,  A61K38/00

摘要： The present invention is directed to a novel plexin family like DNA, a gene containing the DNA, novel polypeptide encoded by the DNA, a recombinant protein containing the polypeptide or heterologous polypeptide sequences, antibodies which bind to the polypeptides, methods for producing the polypeptides of the present invention. Conditions that can be diagnosed, screened, prevented, or treated by the compositions herein include prophylactic, angiogenesis and conservation of functions in various organs, angiogenesis at the time of tumor and regeneration of various organs, proliferation, differentiation and preservation of function of the cells in various organs, aging, and dysfunction of the present invention.

摘要翻译： 本发明涉及一种新型的plexin家族如DNA，含有该DNA的基因，由该DNA编码的新型多肽，含有该多肽或异源多肽序列的重组蛋白，与该多肽结合的抗体，产生多肽的多肽的方法 本发明。 可以通过本文组合物诊断，筛选，预防或治疗的病症包括各种器官的功能的预防，血管生成和保护，肿瘤时的血管发生和各种器官的再生，细胞的功能的增殖，分化和保存 在本发明的各种器官，衰老和功能障碍中。

公开(公告)号：US20060203097A1

公开(公告)日：2006-09-14

申请号：US10566185

申请日：2004-07-29

申请人： Hisashi Koga

发明人： Hisashi Koga

IPC分类号： H04N5/232 ,  H04N7/18 ,  G08B1/00

CPC分类号： H04N5/23206 ,  H04N5/23203 ,  H04N7/142

摘要： The invention, receiving a camera operation screen request from a client terminal, determines a code to be transmitted to the client terminal and transmits the code to the client terminal together with camera operation screen information, registers to a memory a code attached to a drive request signal transmitted from the client terminal, and, receiving a drive request signal from a client terminal, controls the camera in accordance with the signal in case a code matching a registered code is included, and rejects the drive request in case a code matching the registered code is not included. With this configuration, when a plurality of users operate a common camera unit via a network, a code determned by the camera unit is returned from a client terminal and the client terminal is identified based on whether the code is matching. This eliminates the needs for issuing a special id for identifying a client termnal and allows easy operation anywhere from the network by using a general-purpose browser.

摘要翻译： 本发明从客户终端接收相机操作屏幕请求，确定要发送给客户终端的代码，并将该代码与相机操作画面信息一起发送给客户终端，向存储器注册附加到驱动器请求的代码 从客户端发送的信号，以及从客户终端接收驱动请求信号，在包括与注册代码相匹配的代码的情况下，根据该信号来控制相机，并且在符合注册码的代码的情况下拒绝驱动请求 代码不包括在内。 利用该配置，当多个用户经由网络操作公共摄像机单元时，由客户终端返回由相机单元确定的代码，并且基于代码是否匹配来识别客户终端。 这消除了发出用于识别客户端的特殊ID的需要，并且可以通过使用通用浏览器在网络的任何地方轻松进行操作。

公开(公告)号：US08918922B2

公开(公告)日：2014-12-30

申请号：US13876143

申请日：2011-09-26

申请人： Tsutomu Kido ,  Yukinori Kubozono ,  Haruki Matsuda ,  Hisashi Koga

发明人： Tsutomu Kido ,  Yukinori Kubozono ,  Haruki Matsuda ,  Hisashi Koga

IPC分类号： E03D1/14

CPC分类号： E03D1/34 ,  E03D1/35

摘要： A water discharge valve device includes: a water discharge valve unit which has a valve element for opening and closing a discharge port and a control casing for controlling an up-down movement of the valve element; a casing module which includes a peripheral wall extending upwardly from a bottom wall of a water storage tank while surrounding peripheries of the discharge port and the control casing of the water discharge valve unit, to define an upwardly open space therebetween, an opening formed to penetrate through the peripheral wall, and a switching valve attached to the peripheral wall and adapted to open and close the opening; and a communication port formed in a peripheral plane extending from the control casing of the water discharge valve unit to the discharge port, to provide fluid communication between the casing module and the discharge port.

摘要翻译： 排水阀装置包括：排水阀单元，其具有用于打开和关闭排出口的阀元件和用于控制阀元件的上下运动的控制壳体; 壳体模块，其包括从储水箱的底壁向上延伸的外围壁，同时围绕排水口的周边和排水阀单元的控制壳体，以在其间限定向上开放的空间，形成为穿透的开口 通过周壁，以及附接到周壁并适于打开和关闭开口的切换阀; 以及形成在从排水阀单元的控制壳体延伸到排出口的周边平面中的连通口，以在壳体模块和排出口之间提供流体连通。

公开(公告)号：US08745772B2

公开(公告)日：2014-06-10

申请号：US13442774

申请日：2012-04-09

申请人： Tsutomu Kido ,  Yukinori Kubozono ,  Haruki Matsuda ,  Hisashi Koga

发明人： Tsutomu Kido ,  Yukinori Kubozono ,  Haruki Matsuda ,  Hisashi Koga

IPC分类号： E03D1/34

CPC分类号： E03D1/142 ,  E03D1/34

摘要： A discharge valve apparatus has control cylinder members for controlling the flow of rinse water flowing out from a reservoir tank discharge port, on which opening portions are formed, and flow-adjusting members attached to these control cylinder members are capable of adjusting the opening surface area of opening portions in the control cylinder member. Female engaging portions in the control cylinder member are arrayed approximately vertically, and are furnished with registration indentations for registering the attachment positions of adjusting members relative to the control cylinder members. Intervals within the registration indentations are set to be smaller than a width of an installer's finger to prevent release of engagement by an installer when the adjusting member male engaging portions are in a state of engagement with the female engaging portions of the control cylinder members.

摘要翻译： 排气阀装置具有用于控制从形成有开口部的储存箱排出口流出的冲洗水的流动的控制缸构件，并且附接到这些控制缸构件的流量调节构件能够调节开口面积 的控制筒构件中的开口部。 控制筒构件中的阴接合部分大致垂直地排列，并且配备有用于对准调节构件相对于控制缸构件的安装位置的配准凹口。 配准凹口内的间隔被设定为小于安装者手指的宽度，以防止当调节构件公接合部分处于与控制缸构件的阴接合部分接合的状态时由安装者释放接合。

公开(公告)号：US20090112479A1

公开(公告)日：2009-04-30

申请号：US11996473

申请日：2006-05-30

申请人： Makoto Kawai ,  Hisashi Koga ,  Masatoshi Murakami

发明人： Makoto Kawai ,  Hisashi Koga ,  Masatoshi Murakami

IPC分类号： G01N33/48

CPC分类号： G16B45/00 ,  G16B5/00 ,  G16B25/00

摘要： A pathway display method in an information processing device processing information includes a pathway information acquiring step (S10), an expression information identifying step (S11), an expression information acquiring step (S12), and a dynamic image display step (S13).

摘要翻译： 信息处理设备处理信息中的路径显示方法包括路径信息获取步骤（S10），表情信息识别步骤（S11），表情信息获取步骤（S12）和动态图像显示步骤（S13）。