公开(公告)号：US20220018656A1

公开(公告)日：2022-01-20

申请号：US17377439

申请日：2021-07-16

申请人： Shih-Yao PAN ,  Chih-Yao TING ,  Chia-Hung LIN ,  Hsin-Yun CHANG

发明人： Shih-Yao PAN ,  Chih-Yao TING ,  Chia-Hung LIN ,  Hsin-Yun CHANG

IPC分类号： G01B11/30

摘要： Herein disclosed are a surface topography measuring system and a method thereof. The method comprises the following steps: dividing a test beam into a first sub-beam, entering a reflecting mirror along a first axis, and a second sub-beam, entering an object surface along a second axis; moving the reflecting mirror for reflecting the first sub-beam at different positions on the first axis to generate N reflected beams; generating an object reflected beam, related to the second sub-beam, reflected from the object surface; generating N images, related to the N reflected beams and the object reflected beam, and each of the N images having a plurality of interference fringes; analyzing the interference fringes in each of the N images to calculate N curve formulas; calculating a surface topography of the object surface from the N curve formulas.

公开(公告)号：US20080316490A1

公开(公告)日：2008-12-25

申请号：US11812489

申请日：2007-06-19

申请人： Ta-Jen Yen ,  Chung-Tien Li ,  Hsin-Yun Chang ,  You-Lun Guan

发明人： Ta-Jen Yen ,  Chung-Tien Li ,  Hsin-Yun Chang ,  You-Lun Guan

IPC分类号： G01N21/55

CPC分类号： G01N21/554 ,  G01N21/7743

摘要： The present invention discloses a planar surface plasmon resonance detector, wherein a periodic metallic grating structure is arranged on a common glass substrate to replace prisms and generate surface plasmon resonance. The shift of the wavelength or incident angle for surface plasmon resonance is used to detect biochemical molecules. Further, a low-cost white light-emitting diode replaces laser to function as a light source. Via the metallic grating structure and the white light-emitting diode, the present invention can facilitate a low-cost, compact and portable planar surface plasmon resonance detector and popularize the planar surface plasmon resonance detector.

摘要翻译： 本发明公开了一种平面表面等离子体共振检测器，其中周期性金属光栅结构布置在公共玻璃基板上以代替棱镜并产生表面等离子体共振。 用于表面等离子体共振的波长或入射角的偏移用于检测生化分子。 此外，低成本的白色发光二极管代替激光器作为光源。 通过金属光栅结构和白色发光二极管，本发明可以促进低成本，紧凑和便携的平面表面等离子体共振检测器并普及平面表面等离子体共振检测器。

公开(公告)号：US20110085172A1

公开(公告)日：2011-04-14

申请号：US12970391

申请日：2010-12-16

申请人： Ta-Jen YEN ,  Hsin-Yun Chang ,  Chung-Tien Li

发明人： Ta-Jen YEN ,  Hsin-Yun Chang ,  Chung-Tien Li

IPC分类号： G01N21/55

CPC分类号： G01N21/554 ,  G01N21/7743

摘要： A visualized plasmon resonance biodetector utilizes the surface plasmon resonance to detect a plurality of biochemical molecules, and comprises a substrate, a silver-gold dual-layer structure, and a visible light source. The silver-gold dual-layer structure is formed on the substrate and has an optical grating structure on one side far away from the substrate. In a test, the biochemical molecule combines with the silver-gold dual-layer structure, and the visible light source emits a visible light to illuminate the substrate. Then the silver-gold dual-layer structure on the substrate generates surface plasmon resonance and a reflected light. The user can use his naked eyes to discriminate the reflected lights and learn the component and concentration of the biochemical molecule. Therefore, the biodetector can provide a low-cost and easy-to-operate detection instrument for biotests.

摘要翻译： 可视化的等离子体共振生物检测器利用表面等离子体共振来检测多个生化分子，并且包括基底，银 - 金双层结构和可见光源。 银 - 金双层结构形成在基板上，并且在远离基板的一侧具有光栅结构。 在试验中，生化分子与银 - 金双层结构结合，可见光源发出可见光以照射基底。 然后，衬底上的银 - 金双层结构产生表面等离子体共振和反射光。 用户可以用裸眼辨别反射光，了解生化分子的成分和浓度。 因此，生物测定仪可以为生物测试提供低成本且易于操作的检测仪器。

公开(公告)号：US11841218B2

公开(公告)日：2023-12-12

申请号：US17377439

申请日：2021-07-16

申请人： Shih-Yao Pan ,  Chih-Yao Ting ,  Chia-Hung Lin ,  Hsin-Yun Chang

发明人： Shih-Yao Pan ,  Chih-Yao Ting ,  Chia-Hung Lin ,  Hsin-Yun Chang

IPC分类号： G01B11/30

CPC分类号： G01B11/303

摘要： Herein disclosed are a surface topography measuring system and a method thereof. The method comprises the following steps: dividing a test beam into a first sub-beam, entering a reflecting mirror along a first axis, and a second sub-beam, entering an object surface along a second axis; moving the reflecting mirror for reflecting the first sub-beam at different positions on the first axis to generate N reflected beams; generating an object reflected beam, related to the second sub-beam, reflected from the object surface; generating N images, related to the N reflected beams and the object reflected beam, and each of the N images having a plurality of interference fringes; analyzing the interference fringes in each of the N images to calculate N curve formulas; calculating a surface topography of the object surface from the N curve formulas.

公开(公告)号：US20100277738A1

公开(公告)日：2010-11-04

申请号：US12387336

申请日：2009-04-30

申请人： Ta-Jen Yen ,  Hsin-Yun Chang ,  Chung-Tien Li

发明人： Ta-Jen Yen ,  Hsin-Yun Chang ,  Chung-Tien Li

IPC分类号： G01N21/55

CPC分类号： G01N21/554

摘要： The present invention discloses a visualized plasmon resonance biodetector, which utilizes the surface plasmon resonance to detect a plurality of biochemical molecules, and which comprises a substrate, a silver-gold dual-layer structure, and a visible light source. The silver-gold dual-layer structure is formed on the substrate. In a test, a biochemical molecule combines with the silver-gold dual-layer structure, and the visible light source emits a visible light to illuminate the substrate. Thus, the silver-gold dual-layer structure on the substrate generates surface plasmon resonance and a reflected light. The user can use his naked eyes to discriminate the reflected lights and learn the component and concentration of the biochemical molecule. Therefore, the present invention can provide a low-cost and easy-to-operate detection instrument for biotests.

摘要翻译： 本发明公开了一种可视化等离子体共振生物检测器，其利用表面等离子体共振来检测多个生化分子，其包括基底，银 - 金双层结构和可见光源。 在基板上形成银 - 金双层结构。 在试验中，生化分子与银 - 金双层结构结合，可见光源发出可见光以照射基底。 因此，基板上的银 - 金双层结构产生表面等离子体共振和反射光。 用户可以用裸眼辨别反射光，了解生化分子的成分和浓度。 因此，本发明可以提供用于生物测试的低成本和易于操作的检测仪器。