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公开(公告)号：US20150209484A1
公开(公告)日：2015-07-30
申请号：US14164258
申请日：2014-01-27
Applicant: Luke Lu , Toshihiro Tokizawa , Kuan-Yu Lu , I-Ching Lu
Inventor： Luke Lu , Toshihiro Tokizawa , Kuan-Yu Lu , I-Ching Lu
CPC classification number: A61B17/68 , A61B17/7002 , A61B17/80 , A61B17/866 , A61B17/869 , A61F2/28 , A61L31/026 , A61L31/028 , A61L31/044 , A61L31/086 , A61L31/10 , A61L31/16 , A61L2430/02
Abstract: The present invention provides a bone connection material that includes an internal layer. The internal layer is formed by braiding a plurality of filaments. The internal layer that is formed by braiding filaments is resistant to lateral shearing forces and may provide flexibility so as to achieve wide applications. Further, the present invention overcomes the drawback of the conventionally used metallic materials that are rigid and inelastic and also overcomes the problem of polylactic acid material of being brittle. Thus, the bone formed according to the present invention is close to a natural bone and is more suitable for uses in portions where frequent movements are made and scaffolds of stem cells.
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2.发明申请In vivo assay for neurite outgrowth in zebrafish and its application in drug screening 有权斑马鱼神经突生长的体内测定及其在药物筛选中的应用公开(公告)号：US20060179506A1
公开(公告)日：2006-08-10
申请号：US11327263
申请日：2006-01-06
Applicant: Chih-Ming Chou , I-Ching Lu , Gen-Der Chen , Chioh-Yueh Chen , Chang-Jen Huang
Inventor： Chih-Ming Chou , I-Ching Lu , Gen-Der Chen , Chioh-Yueh Chen , Chang-Jen Huang
IPC: A01K67/027
CPC classification number: A01K67/0275 , A01K2217/05 , A01K2227/40 , A01K2267/03 , A01K2267/035 , C12N15/8509
Abstract: A genetically modified zebrafish embryo, comprising a HBNF cDNA or a NGF cDNA or a GDNF cDNA together with a cDNA encoding green fluorescent protein (GFP) so as to induce neurite outgrowth during said zebrafish embryonic development, and a method of using such genetically modified zebrafish embryo to identify a therapeutic agent are disclosed.
Abstract translation: 一种经遗传修饰的斑马鱼胚胎，其包含HBNF cDNA或NGF cDNA或GDNF cDNA以及编码绿色荧光蛋白（GFP）的cDNA，以便在所述斑马鱼胚胎发育过程中诱导神经突生长，以及使用这种转基因斑马鱼 公开了确定治疗剂的胚胎。
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Patent Agency Ranking
公开(公告)号：US20150209095A1
公开(公告)日：2015-07-30
申请号：US14607088
申请日：2015-01-28
Applicant: Luke Lu , Toshihiro Tokizawa , Kuan-Yu Lu , I-Ching Lu
Inventor： Luke Lu , Toshihiro Tokizawa , Kuan-Yu Lu , I-Ching Lu
CPC classification number: A61B17/68 , A61B17/7002 , A61B17/80 , A61B17/866 , A61F2/28 , A61F2/30965 , A61F2002/30009 , A61F2002/30067 , A61F2310/00982 , A61L31/026 , A61L31/028 , A61L31/044 , A61L31/086 , A61L31/16 , A61L31/18 , A61L2430/02
Abstract: The present invention provides a bone connection material that includes an internal layer. The internal layer is formed by braiding a plurality of filaments. The internal layer that is formed by braiding filaments is resistant to lateral shearing forces and may provide flexibility so as to achieve wide applications. Further, the present invention overcomes the drawback of the conventionally used metallic materials that are rigid and inelastic and also overcomes the problem of polylactic acid material of being brittle. Thus, the bone formed according to the present invention is close to a natural bone and is more suitable for uses in portions where frequent movements are made and scaffolds of stem cells.
Abstract translation: 本发明提供一种包括内层的骨连接材料。 内层通过编织多根长丝而形成。 由编织丝形成的内层可抗横向剪切力，并可提供柔性，以达到广泛的应用。 此外，本发明克服了刚性和非弹性的常规使用的金属材料的缺点，并且克服了易碎的聚乳酸材料的问题。 因此，根据本发明形成的骨骼接近天然骨骼，并且更适合用于频繁运动的部分和干细胞支架。
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公开(公告)号：US09408636B2
公开(公告)日：2016-08-09
申请号：US14607088
申请日：2015-01-28
Applicant: Luke Lu , Toshihiro Tokizawa , Kuan-Yu Lu , I-Ching Lu
Inventor： Luke Lu , Toshihiro Tokizawa , Kuan-Yu Lu , I-Ching Lu
IPC: A61B17/68 , A61B17/86 , A61B17/80 , A61L31/02 , A61L31/08 , A61L31/04 , A61F2/28 , A61B17/70 , A61L31/18 , A61L31/16
CPC classification number: A61B17/68 , A61B17/7002 , A61B17/80 , A61B17/866 , A61F2/28 , A61F2/30965 , A61F2002/30009 , A61F2002/30067 , A61F2310/00982 , A61L31/026 , A61L31/028 , A61L31/044 , A61L31/086 , A61L31/16 , A61L31/18 , A61L2430/02
Abstract: The present invention provides a bone connection material that includes an internal layer. The internal layer is formed by braiding a plurality of filaments. The internal layer that is formed by braiding filaments is resistant to lateral shearing forces and may provide flexibility so as to achieve wide applications. Further, the present invention overcomes the drawback of the conventionally used metallic materials that are rigid and inelastic and also overcomes the problem of polylactic acid material of being brittle. Thus, the bone formed according to the present invention is close to a natural bone and is more suitable for uses in portions where frequent movements are made and scaffolds of stem cells.
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5.发明授权In vivo assay for neurite outgrowth in zebrafish and its application in drug screening 有权斑马鱼神经突生长的体内测定及其在药物筛选中的应用公开(公告)号：US07671251B2
公开(公告)日：2010-03-02
申请号：US11327263
申请日：2006-01-06
Applicant: Chih-Ming Chou , I-Ching Lu , Gen-Der Chen , Chioh-Yueh Chen , Chang-Jen Huang
Inventor： Chih-Ming Chou , I-Ching Lu , Gen-Der Chen , Chioh-Yueh Chen , Chang-Jen Huang
IPC: A01K67/027 , G01N33/00
CPC classification number: A01K67/0275 , A01K2217/05 , A01K2227/40 , A01K2267/03 , A01K2267/035 , C12N15/8509
Abstract: A genetically modified zebrafish embryo, comprising a HBNF cDNA or a NGF cDNA or a GDNF cDNA together with a cDNA encoding green fluorescent protein (GFP) so as to induce neurite outgrowth during said zebrafish embryonic development, and a method of using such genetically modified zebrafish embryo to identify a therapeutic agent are disclosed.
Abstract translation: 一种经遗传修饰的斑马鱼胚胎，其包含HBNF cDNA或NGF cDNA或GDNF cDNA以及编码绿色荧光蛋白（GFP）的cDNA，以便在所述斑马鱼胚胎发育过程中诱导神经突生长，以及使用这种转基因斑马鱼 公开了确定治疗剂的胚胎。
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公开(公告)号：US09370381B2
公开(公告)日：2016-06-21
申请号：US14164258
申请日：2014-01-27
Applicant: Luke Lu , Toshihiro Tokizawa , Kuan-Yu Lu , I-Ching Lu
Inventor： Luke Lu , Toshihiro Tokizawa , Kuan-Yu Lu , I-Ching Lu
IPC: A61B17/68 , A61L31/08 , A61B17/86 , A61L31/04 , A61L31/02 , A61L31/10 , A61L31/16 , A61F2/28 , A61B17/70 , A61B17/80
CPC classification number: A61B17/68 , A61B17/7002 , A61B17/80 , A61B17/866 , A61B17/869 , A61F2/28 , A61L31/026 , A61L31/028 , A61L31/044 , A61L31/086 , A61L31/10 , A61L31/16 , A61L2430/02
Abstract: The present invention provides a bone connection material that includes an internal layer. The internal layer is formed by braiding a plurality of filaments. The internal layer that is formed by braiding filaments is resistant to lateral shearing forces and may provide flexibility so as to achieve wide applications. Further, the present invention overcomes the drawback of the conventionally used metallic materials that are rigid and inelastic and also overcomes the problem of polylactic acid material of being brittle. Thus, the bone formed according to the present invention is close to a natural bone and is more suitable for uses in portions where frequent movements are made and scaffolds of stem cells.
Abstract translation: 本发明提供一种包括内层的骨连接材料。 内层通过编织多根长丝而形成。 由编织丝形成的内层可抗横向剪切力，并可提供柔性，以达到广泛的应用。 此外，本发明克服了刚性和非弹性的常规使用的金属材料的缺点，并且克服了易碎的聚乳酸材料的问题。 因此，根据本发明形成的骨骼接近天然骨骼，并且更适合用于频繁运动的部分和干细胞支架。
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公开(公告)号：US20150277015A1
公开(公告)日：2015-10-01
申请号：US14228272
申请日：2014-03-28
Applicant: Luke Lu , Toshihiro Tokizawa , Kuan-Yu Lu , I-Ching Lu
Inventor： Luke Lu , Toshihiro Tokizawa , Kuan-Yu Lu , I-Ching Lu
CPC classification number: A61B1/00165 , A61B90/30 , A61B2090/306 , G02B6/0008
Abstract: The present invention relates to a light guide tube, which is formed by weaving a plurality of filaments to provide a single-hole or multi-hole tube. Further, the filaments include filaments that are made of at least one light-transmittable material. With the single-hole or multi-hole tube formed by weaving filaments, besides strengthening the capability of enduring sideways stress, a light-emitting unit can be additionally included at a front end of the tube for illumination purposes and formation can be achieved by using various types of filaments to suit practical needs, such as combination with metal wires or electrical signal carrier material for purposes of transmission of electrical power or electronic information, thereby achieving a wider range of applications that the conventional tubes.
Abstract translation: 本发明涉及一种导光管，其通过编织多根细丝而形成以提供单孔或多孔管。 此外，长丝包括由至少一种可透光材料制成的细丝。 对于通过编织细丝形成的单孔或多孔管，除了加强耐受侧向应力的能力外，还可以在管的前端另外包含发光单元以用于照明目的，并且可以通过使用 各种类型的细丝，以适应实际需要，例如与用于传输电力或电子信息的金属线或电信号载体材料的组合，从而实现传统管的更广泛的应用范围。
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