Abstract:
Radiolabeled dihematoporphyrin ether having the following general formula ##STR1## wherein at least one of R.sub.1 -R.sub.6 is a moiety labeled with a radionuclide imaging agent is useful in providing a non-invasive nuclear scintillation image. This dihematoporphyrin ether localizes in neoplastic tissue and thus provides a method of imaging and recording the location of neoplastic tissue. When the labeling agent has an adequate component of particulate radiation, the dihematoporphyrin ether can be used as a therapeutic agent as well as a diagnostic imaging agent.
Abstract:
This disclosure provides articles that include functionalized nanoscale fibers and methods for functionalizing nanoscale fibers. The functionalized nanoscale fibers may be made by oxidizing a network of nanoscale fibers, grafting one or more molecules or polymers to the oxidized nanoscale fibers, and cross-linking at least a portion of the molecules or polymers grafted to the oxidized nanoscale fibers. The functionalized nanoscale fibers may be used to make articles.