Radio labeled dihematophorphyrin ether and its use in detecting and
treating neoplastic tissue
    1.
    发明授权
    Radio labeled dihematophorphyrin ether and its use in detecting and treating neoplastic tissue 失效
    无机标记的二氢吡啶醚及其在检测和处理神经组织中的应用

    公开(公告)号:US5104637A

    公开(公告)日:1992-04-14

    申请号:US698565

    申请日:1985-02-06

    CPC classification number: A61K51/0485 C07D519/00 A61K2123/00

    Abstract: Radiolabeled dihematoporphyrin ether having the following general formula ##STR1## wherein at least one of R.sub.1 -R.sub.6 is a moiety labeled with a radionuclide imaging agent is useful in providing a non-invasive nuclear scintillation image. This dihematoporphyrin ether localizes in neoplastic tissue and thus provides a method of imaging and recording the location of neoplastic tissue. When the labeling agent has an adequate component of particulate radiation, the dihematoporphyrin ether can be used as a therapeutic agent as well as a diagnostic imaging agent.

    Abstract translation: 具有以下通式的放射性标记的二头卟啉醚,其中R 1 -R 6中的至少一个是用放射性核素显像剂标记的部分,可用于提供非侵入式核闪烁图像。 这种脱水卟啉醚定位在肿瘤组织中,因此提供了成像和记录肿瘤组织位置的方法。 当标记剂具有足够的颗粒物辐射成分时,可使用二头卟啉醚作为治疗剂以及诊断显像剂。

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