METHOD FOR PRODUCING 5-HALOMETHYLFURFURAL AND SYSTEM THEREFOR

    公开(公告)号:US20250059148A1

    公开(公告)日:2025-02-20

    申请号:US18701820

    申请日:2022-10-20

    Abstract: According to the present disclosure, by forming normal pressure conditions in a reaction system through application of a reflux system to an aqueous phase in the presence of sulfuric acid and an inorganic salt in the dehydration reaction of biomass-derived sugar components in an open system, there is no need to include a high-pressure vessel required in a conventional 5-halomethylfurfural production process, there is no risk of safety accidents, including the explosion of a high-pressure vessel and the leakage of strong acid gas, and there is a remarkable effect in that yield is improved three-fold or more compared to the case of using a conventionally used acid catalyst under the normal pressure conditions.

    Transmembrane domain derived from human LRRC24 protein

    公开(公告)号:US12202876B2

    公开(公告)日:2025-01-21

    申请号:US17296622

    申请日:2019-12-16

    Abstract: The present invention relates to a transmembrane domain derived from human LRRC24 protein. More specifically, the present invention relates to a transmembrane domain derived from the human LRRC24 protein (LRRC24P transmembrane domain) or a cell-penetrating peptide, and an intracellular delivery system comprising same. The transmembrane domain derived from the human LRRC24 protein of the present invention can be used to deliver cargo materials such as compounds, biomolecules, and various polymer materials into cells. Since the LRRC24P transmembrane domain of the present invention exhibits higher cell penetration efficiency compared to conventional cell-penetrating peptides and is derived from human proteins, thus avoiding side effects and immune responses caused by peptides derived from foreign proteins, it can be usefully used as an effective intracellular delivery method for compounds, biomolecules, and various polymer materials applied to the human body.

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