公开(公告)号：US5843706A

公开(公告)日：1998-12-01

申请号：US483812

申请日：1995-06-07

申请人： Gary Stewart Cobon ,  Rosemary Ann Austen ,  Ian Joseph O'Donnell ,  Maurice Joseph Frenkel ,  William Peter Keith Kennedy ,  Keith William Savin ,  Barry Maxwell Wagland

发明人： Gary Stewart Cobon ,  Rosemary Ann Austen ,  Ian Joseph O'Donnell ,  Maurice Joseph Frenkel ,  William Peter Keith Kennedy ,  Keith William Savin ,  Barry Maxwell Wagland

IPC分类号： G01N33/569 ,  A61K39/00 ,  A61K39/395 ,  C07K14/00 ,  C07K14/435 ,  C07K14/44 ,  C07K16/00 ,  C07K16/18 ,  C12N1/21 ,  C12N15/09 ,  C12N15/12 ,  C12P21/02 ,  C12P21/08 ,  C12R1/19 ,  G01N33/577 ,  C12N15/00 ,  C07H21/04

CPC分类号： C07K14/4354 ,  A61K39/0003 ,  C07K16/18 ,  A61K39/00

摘要： The invention disclosed relates to proteins derived from parasitic nematodes that confer protective immunity against infection by parasitic nematodes, to nucleotide sequences encoding those proteins, to recombinant molecules containing such sequences, to host cells transformed with such recombinant molecules and methods for the production of the nucleotide sequences, recombinant molecules and hosts. The invention also relates to vaccines comprising proteins of the invention together with suitable carriers or diluents and to antibodies raised against proteins of the invention.

摘要翻译： 所公开的发明涉及将寄生线虫感染的保护性免疫，编码这些蛋白质的核苷酸序列，含有这些序列的重组分子，赋予用这种重组分子转化的宿主的寄生线虫的蛋白质，以及生产该核苷酸的方法 序列，重组分子和宿主。 本发明还涉及包含本发明的蛋白质与合适的载体或稀释剂以及针对本发明的蛋白质产生的抗体的疫苗。

公开(公告)号：US5843710A

公开(公告)日：1998-12-01

申请号：US482547

申请日：1995-06-07

申请人： Gary Stewart Cobon ,  Rosemary Ann Austen ,  Ian Joseph O'Donnell ,  Maurice Joseph Frenkel ,  William Peter Keith Kennedy ,  Keith William Savin ,  Barry Maxwell Wagland

发明人： Gary Stewart Cobon ,  Rosemary Ann Austen ,  Ian Joseph O'Donnell ,  Maurice Joseph Frenkel ,  William Peter Keith Kennedy ,  Keith William Savin ,  Barry Maxwell Wagland

IPC分类号： A61K39/00 ,  C07K14/435 ,  C07K16/18 ,  C07K14/00

CPC分类号： A61K39/0003 ,  C07K14/4354 ,  C07K16/18 ,  A61K39/00

摘要： Disclosed is the invention relates to proteins derived from parasitic nematodes which confer protective immunity against infection by parasitic nematodes, to nucleotide sequences encoding these proteins, to recombinant molecules containing such sequences to host cells transformed with such recombinant molecules and methods for the production of the nucleotide sequences recombinant molecules and hosts. The invention also relates to vaccines comprising proteins of the invention together with suitable carriers or diluents and to antibodies raised against proteins of the invention.

摘要翻译： 本发明涉及来自寄生线虫的蛋白质，其赋予寄生线虫感染的保护性免疫力，编码这些蛋白质的核苷酸序列，含有这样的序列的重组分子，以宿主用这种重组分子转化的细胞和用于产生核苷酸的方法 序列重组分子和宿主。 本发明还涉及包含本发明的蛋白质与合适的载体或稀释剂以及针对本发明的蛋白质产生的抗体的疫苗。