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公开(公告)号:US09421254B2
公开(公告)日:2016-08-23
申请号:US12679881
申请日:2008-09-24
申请人: Jay A. Berzofsky , Qing Zhu , Igor Belyakov
发明人: Jay A. Berzofsky , Qing Zhu , Igor Belyakov
CPC分类号: A61K39/39 , A61K39/21 , A61K2039/55516 , A61K2039/55561 , A61K2039/57 , C12N7/00 , C12N2740/16034 , Y02A50/394
摘要: The present invention provides immunostimulatory combinations of TLR ligands and therapeutic and/or prophylactic methods that include administering an immunostimulatory combination to a subject. In general, the immunostimulatory combinations described herein can provide an increased immune response compared to other immunostimulatory combinations and/or compositions.
摘要翻译: 本发明提供了TLR配体的免疫刺激组合以及治疗和/或预防方法,其包括对受试者施用免疫刺激组合。 通常,与其它免疫刺激组合和/或组合物相比,本文所述的免疫刺激组合可以提供增加的免疫应答。
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公开(公告)号:US20050232897A1
公开(公告)日:2005-10-20
申请号:US10815340
申请日:2004-03-30
申请人: Jay Berzofsky , Igor Belyakov , Michael Derby , Brian Kelsall , Warren Strober
发明人: Jay Berzofsky , Igor Belyakov , Michael Derby , Brian Kelsall , Warren Strober
IPC分类号: A61K39/21 , C07K14/16 , A61K39/108 , A61K38/21 , A61K39/02
CPC分类号: C07K14/005 , A61K39/12 , A61K39/21 , A61K2039/5256 , A61K2039/541 , A61K2039/545 , A61K2039/55522 , A61K2039/55538 , A61K2039/55544 , A61K2039/55566 , A61K2039/6037 , C12N2710/24143 , C12N2740/16122 , C12N2740/16134 , Y10S530/826
摘要: The invention provides methods for induction of an antigen-specific, mucosal cytotoxic T lymphocyte response useful in preventing and treating infections with pathogens that gain entry via a mucosal surface.
摘要翻译: 本发明提供用于诱导抗原特异性粘膜细胞毒性T淋巴细胞应答的方法,所述抗原特异性粘膜细胞毒性T淋巴细胞应答可用于预防和治疗通过粘膜表面进入的病原体的感染。
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