公开(公告)号：US20050232897A1

公开(公告)日：2005-10-20

申请号：US10815340

申请日：2004-03-30

申请人： Jay Berzofsky ,  Igor Belyakov ,  Michael Derby ,  Brian Kelsall ,  Warren Strober

发明人： Jay Berzofsky ,  Igor Belyakov ,  Michael Derby ,  Brian Kelsall ,  Warren Strober

IPC分类号： A61K39/21 ,  C07K14/16 ,  A61K39/108 ,  A61K38/21 ,  A61K39/02

CPC分类号： C07K14/005 ,  A61K39/12 ,  A61K39/21 ,  A61K2039/5256 ,  A61K2039/541 ,  A61K2039/545 ,  A61K2039/55522 ,  A61K2039/55538 ,  A61K2039/55544 ,  A61K2039/55566 ,  A61K2039/6037 ,  C12N2710/24143 ,  C12N2740/16122 ,  C12N2740/16134 ,  Y10S530/826

摘要： The invention provides methods for induction of an antigen-specific, mucosal cytotoxic T lymphocyte response useful in preventing and treating infections with pathogens that gain entry via a mucosal surface.

摘要翻译： 本发明提供用于诱导抗原特异性粘膜细胞毒性T淋巴细胞应答的方法，所述抗原特异性粘膜细胞毒性T淋巴细胞应答可用于预防和治疗通过粘膜表面进入的病原体的感染。

公开(公告)号：US20200175803A1

公开(公告)日：2020-06-04

申请号：US16702408

申请日：2019-12-03

申请人： MICHAEL DERBY

发明人： MICHAEL DERBY

IPC分类号： G07F11/00 ,  G07F13/02 ,  B67D7/04 ,  B67D7/14 ,  G06Q20/20 ,  G06Q20/32

摘要： A system facilitating payment for fuel dispensing includes a fuel dispenser associated with a current-loop-to-ethernet converter for receiving serial data from a fuel dispenser controller and converting said serial data to an ethernet signal and a network appliance coupled the current-loop-to-ethernet converter by an ethernet port. A virtual payment facilitator is connected to the network appliance over a VPN and to a payment authorization entity, also over a VPN. A process performed by the system includes receiving a fueling request at the virtual payment facilitator from the payment authorization entity and converting that request into a command issued to the fuel dispenser to dispense fuel.

公开(公告)号：US08695697B2

公开(公告)日：2014-04-15

申请号：US12697958

申请日：2010-02-01

申请人： Michael Derby

发明人： Michael Derby

IPC分类号： E21B33/12

CPC分类号： E21B33/1285 ,  E21B33/1208

摘要： A downhole tool has a mandrel with packing elements. Collars between the packing elements define ports communicating with gaps between the packing elements and the mandrels. Opposing piston housings on the mandrel can move in opposing directions to compress the packing elements against the collars. Each piston housing defines a space with the mandrel and has a second port communicating with the gap. Pistons disposed in the spaces are temporarily affixed thereto. Hydraulic pressure communicated through the mandrel's bore acts against the pistons. While affixed to the piston housings, the pistons move the piston housings toward the packing elements to compress then. When the packing elements set, continued pressure breaks shear pins affixing the pistons to the piston housings so the pistons move and eventually seal fluid communication between the second ports in the pistons and the gaps.

摘要翻译： 井下工具具有具有包装元件的心轴。 包装元件之间的环形部分限定了与包装元件和心轴之间的间隙连通的端口。 心轴上的相对的活塞壳体可以沿相反的方向运动，以将衬垫元件压靠在套环上。 每个活塞壳体与心轴形成一个空间，并且具有与间隙连通的第二端口。 安置在空间中的活塞暂时固定在其上。 通过心轴的孔连通的液压作用在活塞上。 在固定到活塞壳体上时，活塞将活塞壳体朝向包装元件移动，从而压缩。 当包装元件设置时，持续的压力破坏将活塞固定到活塞壳体上的剪切销，使得活塞移动并最终密封活塞中的第二端口与间隙之间的流体连通。

公开(公告)号：US20110186307A1

公开(公告)日：2011-08-04

申请号：US12697958

申请日：2010-02-01

申请人： Michael Derby

发明人： Michael Derby

IPC分类号： E21B33/12

CPC分类号： E21B33/1285 ,  E21B33/1208

摘要： A downhole tool has a mandrel with packing elements. Collars between the packing elements define ports communicating with gaps between the packing elements and the mandrels. Opposing piston housings on the mandrel can move in opposing directions to compress the packing elements against the collars. Each piston housing defines a space with the mandrel and has a second port communicating with the gap. Pistons disposed in the spaces are temporarily affixed thereto. Hydraulic pressure communicated through the mandrel's bore acts against the pistons. While affixed to the piston housings, the pistons move the piston housings toward the packing elements to compress then. When the packing elements set, continued pressure breaks shear pins affixing the pistons to the piston housings so the pistons move and eventually seal fluid communication between the second ports in the pistons and the gaps.

摘要翻译： 井下工具具有具有包装元件的心轴。 包装元件之间的环形部分限定了与包装元件和心轴之间的间隙连通的端口。 心轴上的相对的活塞壳体可以沿相反的方向运动，以将衬垫元件压靠在套环上。 每个活塞壳体与心轴形成一个空间，并且具有与间隙连通的第二端口。 安置在空间中的活塞暂时固定在其上。 通过心轴的孔连通的液压作用在活塞上。 在固定到活塞壳体上时，活塞将活塞壳体朝向包装元件移动，从而压缩。 当包装元件设置时，持续的压力破坏将活塞固定到活塞壳体上的剪切销，使得活塞移动并最终密封活塞中的第二端口与间隙之间的流体连通。