ANTIBACTERIAL MACROLACTIN A THAT BACILLUS POLYFERMENTICUS KJS-2 PRODUCED IN
    4.
    发明申请
    ANTIBACTERIAL MACROLACTIN A THAT BACILLUS POLYFERMENTICUS KJS-2 PRODUCED IN 审中-公开
    抗生素大豆蛋白A生产的BACILLUS POLYFERMENKUS KJS-2

    公开(公告)号:US20100087516A1

    公开(公告)日:2010-04-08

    申请号:US12531434

    申请日:2008-03-12

    IPC分类号: A61K31/335 A61P31/12 C12N1/20

    CPC分类号: C12P17/08 C07D313/00 C12R1/07

    摘要: The present invention relates to uses of Macrolactin A produced by Bacillus polyfermenticus KJS-2 (KCCM 10769P), which is a new bacillus strain, as an antibiotic. Macrolactin A of the present invention, which is produced by Bacillus polyfermenticus KJS-2, shows a broad spectrum of antibiotic activity against a variety of microorganisms and fungi, and is proved to be very efficient for the inhibition of particularly vancomycin-resistant enterococci (VRE) and methicillin-resistant Staphylococcus Aureus (MRSA) that are multidrug-resistant bacteria. The antibiotic Macrolactin A produced by Bacillus polyfermenticus KJS-2, can be used as an excellent antibiotic against vancomycin-resistant enterococci (VRE) and methicillin-resistant Staphylococcus Aureus (MRSA), and thus the present invention is a very useful invention for medical industry.

    摘要翻译: 本发明涉及作为新型芽孢杆菌菌株的作为抗生素的由Bacillus polyfermenticus KJS-2(KCCM 10769P)生产的Mac lactin A的用途。 由多发芽孢杆菌KJS-2生产的本发明的大肠杆菌素A表现出对多种微生物和真菌的广谱抗生素活性,并被证明对于特别是耐万古霉素耐药性肠球菌(VRE)的抑制是非常有效的 )和耐甲氧西林金黄色葡萄球菌(MRSA)是多重耐药细菌。 通过芽孢杆菌KJS-2生产的抗生素麦脯氨酸A可用作抗万古霉素抗性肠球菌(VRE)和耐甲氧西林金黄色葡萄球菌(MRSA)的优良抗生素,因此本发明是医疗行业非常有用的发明 。