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公开(公告)号：US08609646B2
公开(公告)日：2013-12-17
申请号：US12804029
申请日：2010-07-12
Applicant: Stephen J. Klaus , Christopher J. Molineaux , Thomas B. Neff , Volkmar Guenzler-Pukall , Ingrid Langsetmo Parobok , Todd W. Seeley , Robert C. Stephenson
Inventor： Stephen J. Klaus , Christopher J. Molineaux , Thomas B. Neff , Volkmar Guenzler-Pukall , Ingrid Langsetmo Parobok , Todd W. Seeley , Robert C. Stephenson
CPC classification number: C07D217/24 , A61K31/00 , A61K31/165 , A61K31/17 , A61K31/395 , A61K31/472 , C07C275/40
Abstract: The present invention relates to methods and compounds for decreasing the expression of hepcidin, a protein associated with regulation of iron metabolism.
Abstract translation: 本发明涉及用于降低与铁代谢调节相关的蛋白质铁调素的表达的方法和化合物。
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公开(公告)号：US20120039882A1
公开(公告)日：2012-02-16
申请号：US13279086
申请日：2011-10-21
Applicant: Ingrid Langsetmo Parobok , Christopher T. Jacob , David Y. Liu
Inventor： Ingrid Langsetmo Parobok , Christopher T. Jacob , David Y. Liu
IPC: A61K39/395 , A61P9/00 , A61K31/713 , A61K31/7088 , A61K31/7105
CPC classification number: C07K16/22 , A61K2039/505
Abstract: The present invention relates to methods and agents for treating impaired vascular and cardiac function. Methods and agents for treating various physiological and pathological features associated with vascular dysfunction and cardiac dysfunction are also provided.
Abstract translation: 本发明涉及治疗血管和心脏功能受损的方法和试剂。 还提供了用于治疗与血管功能障碍和心脏功能障碍相关的各种生理和病理特征的方法和试剂。
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公开(公告)号：US20110039879A1
公开(公告)日：2011-02-17
申请号：US12734890
申请日：2008-12-08
Applicant: Stephen J. Klaus , Ingrid Langsetmo Parobok
Inventor： Stephen J. Klaus , Ingrid Langsetmo Parobok
IPC: A61K31/437
CPC classification number: A61K31/472 , A61K31/4738 , A61K31/4743 , A61K31/4745
Abstract: The present invention relates to methods and compounds useful for increasing white blood cell levels in blood and bone marrow. Methods and compounds for increasing hematopoietic progenitor cells are also provided.
Abstract translation: 本发明涉及可用于增加血液和骨髓中白细胞水平的方法和化合物。 还提供了用于增加造血祖细胞的方法和化合物。
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公开(公告)号：US20070072817A1
公开(公告)日：2007-03-29
申请号：US11418974
申请日：2006-05-05
Applicant: Ingrid Langsetmo Parobok , Todd Seeley , Robert Stephenson
Inventor： Ingrid Langsetmo Parobok , Todd Seeley , Robert Stephenson
CPC classification number: C07K16/22 , A61K2039/505
Abstract: The present invention relates to methods and agents for reducing blood pressure. Methods and agents for reducing diastolic blood pressure, for reducing systolic blood pressure, and for reducing mean arterial pressure are also provided.
Abstract translation: 本发明涉及降低血压的方法和试剂。 还提供了用于降低舒张压，降低收缩压和降低平均动脉压的方法和试剂。
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公开(公告)号：US20140163061A1
公开(公告)日：2014-06-12
申请号：US14180720
申请日：2014-02-14
Applicant: Volkmar Guenzler-Pukall , Qingjian Wang , Ingrid Langsetmo Parobok , Guangjie Guo
Inventor： Volkmar Guenzler-Pukall , Qingjian Wang , Ingrid Langsetmo Parobok , Guangjie Guo
IPC: C07D471/04 , C07D217/26
CPC classification number: C07D471/04 , A61K31/437 , A61K31/472 , C07D217/26
Abstract: The present invention provides methods and medicaments for reducing blood pressure. Methods and medicaments for treating or preventing hypertension are also provided.
Abstract translation: 本发明提供用于降低血压的方法和药物。 还提供了治疗或预防高血压的方法和药物。
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Patent Agency Ranking
公开(公告)号：US08614204B2
公开(公告)日：2013-12-24
申请号：US10861590
申请日：2004-06-03
Applicant: Stephen J. Klaus , Christopher J. Molineaux , Thomas B. Neff , Volkmar Guenzler-Pukall , Ingrid Langsetmo Parobok , Todd W. Seeley , Robert C. Stephenson
Inventor： Stephen J. Klaus , Christopher J. Molineaux , Thomas B. Neff , Volkmar Guenzler-Pukall , Ingrid Langsetmo Parobok , Todd W. Seeley , Robert C. Stephenson
CPC classification number: C07D217/24 , A61K31/00 , A61K31/165 , A61K31/17 , A61K31/395 , A61K31/472 , C07C275/40
Abstract: The present invention relates to methods and compounds for regulating or enhancing erythropoiesis and iron metabolism, and for treating or preventing iron deficiency and anemia of chronic disease.
Abstract translation: 本发明涉及用于调节或增强红细胞生成和铁代谢以及治疗或预防慢性疾病的铁缺乏和贫血的方法和化合物。
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公开(公告)号：US20110039885A1
公开(公告)日：2011-02-17
申请号：US12734893
申请日：2008-12-08
Applicant: Stephen J. Klaus , Ingrid Langsetmo Parobok , Oksana Sirenko
Inventor： Stephen J. Klaus , Ingrid Langsetmo Parobok , Oksana Sirenko
IPC: A61K31/47
CPC classification number: A61K31/472
Abstract: The present invention relates to methods and compounds useful for increasing endothelial progenitor cell levels in blood and bone marrow. Methods and compounds for increasing endothelial progenitor cell mobilization are also provided.
Abstract translation: 本发明涉及可用于增加血液和骨髓中内皮祖细胞水平的方法和化合物。 还提供了用于增加内皮祖细胞动员的方法和化合物。
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公开(公告)号：US20060281667A1
公开(公告)日：2006-12-14
申请号：US11418624
申请日：2006-05-05
Applicant: Ingrid Langsetmo Parobok , Christopher Jacob , David Liu
Inventor： Ingrid Langsetmo Parobok , Christopher Jacob , David Liu
IPC: A61K38/17
CPC classification number: C07K16/22 , A61K2039/505
Abstract: The present invention relates to methods and agents for treating impaired vascular and cardiac function. Methods and agents for treating various physiological and pathological features associated with vascular dysfunction and cardiac dysfunction are also provided.
Abstract translation: 本发明涉及治疗血管和心脏功能受损的方法和试剂。 还提供了用于治疗与血管功能障碍和心脏功能障碍相关的各种生理和病理特征的方法和试剂。
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公开(公告)号：US20110263644A1
公开(公告)日：2011-10-27
申请号：US13180262
申请日：2011-07-11
Applicant: Stephen J. Klaus , Ingrid Langsetmo Parobok , Christopher T. Jacob
Inventor： Stephen J. Klaus , Ingrid Langsetmo Parobok , Christopher T. Jacob
IPC: A61K31/472 , A61P9/00 , A61K31/4725
CPC classification number: A61K45/06 , A61K31/121 , A61K31/194 , A61K38/49 , A61K2300/00
Abstract: The present invention relates to methods and agents useful for the treatment of stroke, including ischemic stroke and hemorrhagic stroke. In particular, methods and agents for treating stroke in a subject are provided, wherein the agent is administered prior to diagnosis of the stroke as an ischemic stroke or a hemorrhagic stroke.
Abstract translation: 本发明涉及可用于治疗中风的方法和药剂，包括缺血性卒中和出血性中风。 特别地，提供了用于治疗受试者中风的方法和药剂，其中所述药物在诊断为中风之前作为缺血性中风或出血性中风进行施用。
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公开(公告)号：US20110039878A1
公开(公告)日：2011-02-17
申请号：US12734444
申请日：2008-11-03
Applicant: Volkmar Guenzler-Pukall , Qingjian Wang , Ingrid Langsetmo Parobok , Guangjie Guo
Inventor： Volkmar Guenzler-Pukall , Qingjian Wang , Ingrid Langsetmo Parobok , Guangjie Guo
IPC: A61K31/437 , A61K31/47 , A61P9/12
CPC classification number: C07D471/04 , A61K31/437 , A61K31/472 , C07D217/26
Abstract: The present invention provides methods and medicaments for reducing blood pressure. Methods and medicaments for treating or preventing hypertension are also provided.
Abstract translation: 本发明提供用于降低血压的方法和药物。 还提供了治疗或预防高血压的方法和药物。
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