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公开(公告)号:US20240385089A1
公开(公告)日:2024-11-21
申请号:US18789567
申请日:2024-07-30
Applicant: INNOVAPREP LLC
Inventor: Alec D. Adolphson , Andrew E. Page , John D. Birkenholz , David Goad
Abstract: Devices, systems and methods are disclosed which relate to a prefiltration device that can be used with the concentrating pipette instruments and other devices which draw a sample in through one opening and dispense a concentrated or eluted sample out through the same opening. The device allows the sample to be passed through a prefilter when entering the opening and then bypassed the prefilter when being dispensed through the same opening.
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公开(公告)号:US12013322B2
公开(公告)日:2024-06-18
申请号:US17194169
申请日:2021-03-05
Applicant: INNOVAPREP LLC
Inventor: Andew Edward Page , Zachary A. Packingham , David Scott Alburty , Alec D. Adolphson
CPC classification number: G01N1/4077 , B01L3/0275 , C12Q1/24 , B01L2200/026 , B01L2200/0631 , B01L2300/0681 , B01L2300/161 , G01N2001/4088
Abstract: Highly efficient and rapid filtration-based concentration devices, systems and methods are disclosed with sample fluidic lines and a filter packaged in a disposable tip which concentrate biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. The concentrate is then dispensed from the disposable tip in a set volume of elution fluid. Suspended biological particles include such materials as proteins/toxins, viruses, DNA, and/or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect. All conduits by which the disposable tip attaches to the instrument are combined into a single connection point on the upper end of the tip.
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3.
公开(公告)号:US20240139724A1
公开(公告)日:2024-05-02
申请号:US18384345
申请日:2023-10-26
Applicant: INNOVAPREP LLC
Inventor: Andrew E. Page , David Goad , Steven D. Graham
CPC classification number: B01L3/0217 , A61M5/31565 , B01L3/0275 , G01N35/1004 , B01L2300/0681 , B01L2400/0487 , B01L2400/0622 , B01L2400/0644 , G01N2035/1006
Abstract: Highly efficient and rapid filtration-based concentration devices, systems and methods are disclosed with a rotary distribution valve connected to a syringe pump which maintains control and flow of various fluids to a sample through a retentate port.
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公开(公告)号:US11698328B2
公开(公告)日:2023-07-11
申请号:US16934931
申请日:2020-07-21
Applicant: InnovaPrep LLC
Inventor: Andrew Edward Page , David Scott Alburty , Alec D. Adolphson , Pamela S. Murowchick , Zachary A. Packingham
CPC classification number: G01N1/4077 , B01D46/0032 , B01D46/543 , B01D46/70 , G01N1/2205 , G01N2001/4088
Abstract: Devices, systems and methods are disclosed which relate to using a wet foam elution method for removal of particles from a flat filter. Particles are captured from the atmosphere onto the flat filter. The flat filter is then placed into an extractor which passes a stream of wet foam through the flat filter. Expansion of the foam works to efficiently remove captured particles. The foam flows from the filter along with the captured particles into a sample container. Once in the sample container, the foam quickly breaks down leaving an analysis ready liquid sample.
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公开(公告)号:US20210208032A1
公开(公告)日:2021-07-08
申请号:US17209434
申请日:2021-03-23
Applicant: InnovaPrep LLC
Inventor: Andrew Edward Page , Zachary A. Packingham , David Scott Alburty , Alec D. Adolphson
Abstract: Highly efficient and rapid filtration-based concentration devices, systems and methods are disclosed with sample fluidic lines and a filter packaged in a disposable tip which concentrate biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. The concentrate is then dispensed from the disposable tip in a set volume of elution fluid. Suspended biological particles include such materials as proteins/toxins, viruses, DNA, and/or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect. A single-use pipette tip includes fluid ports for aspirating the sample and connecting to a concentrating unit.
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公开(公告)号:US20200348217A1
公开(公告)日:2020-11-05
申请号:US16934931
申请日:2020-07-21
Applicant: InnovaPrep LLC
Inventor: Andrew Edward Page , David Scott Alburty , Alec D. Adolphson , Pamela S. Murowchick , Zachary A. Packingham
Abstract: Devices, systems and methods are disclosed which relate to using a wet foam elution method for removal of particles from a flat filter. Particles are captured from the atmosphere onto the flat filter. The flat filter is then placed into an extractor which passes a stream of wet foam through the flat filter. Expansion of the foam works to efficiently remove captured particles. The foam flows from the filter along with the captured particles into a sample container. Once in the sample container, the foam quickly breaks down leaving an analysis ready liquid sample.
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公开(公告)号:US10718696B2
公开(公告)日:2020-07-21
申请号:US15397524
申请日:2017-01-03
Applicant: InnovaPrep LLC
Inventor: Andrew Edward Page , David Scott Alburty , Alec D. Adolphson , Pamela S. Murowchick , Zachary A. Packingham
Abstract: Devices, systems and methods are disclosed which relate to using a wet foam elution method for removal of particles from a flat filter. Particles are captured from the atmosphere onto the flat filter. The flat filter is then placed into an extractor which passes a stream of wet foam through the flat filter. Expansion of the foam works to efficiently remove captured particles. The foam flows from the filter along with the captured particles into a sample container. Once in the sample container, the foam quickly breaks down leaving an analysis ready liquid sample.
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公开(公告)号:US12050162B2
公开(公告)日:2024-07-30
申请号:US17726625
申请日:2022-04-22
Applicant: INNOVAPREP LLC
Inventor: Alec D. Adolphson , Andrew E. Page , John D. Birkenholz , David Goad
CPC classification number: G01N1/34 , B01L3/502753 , B01L2300/0681 , B01L2300/0832 , B01L2400/0683
Abstract: Devices, systems and methods are disclosed which relate to a prefiltration device that can be used with the concentrating pipette instruments and other devices which draw a sample in through one opening and dispense a concentrated or eluted sample out through the same opening. The device allows the sample to be passed through a prefilter when entering the opening and then bypassed the prefilter when being dispensed through the same opening.
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公开(公告)号:USD1014779S1
公开(公告)日:2024-02-13
申请号:US29794875
申请日:2021-06-15
Applicant: Boehringer Ingelheim Vetmedica GmbH , INNOVAPREP LLC
Designer: Zachary A. Packingham , Steven D. Graham
Abstract: FIG. 1 is a front perspective view of an aerosol collector showing our new design;
FIG. 2 is a front elevational view thereof;
FIG. 3 is a back elevational view thereof;
FIG. 4 is a right side elevational view thereof;
FIG. 5 is a left side elevational view thereof;
FIG. 6 is a top plan view thereof;
FIG. 7 is a bottom plan view thereof; and,
FIG. 8 is a bottom perspective view thereof.
The broken lines in the drawings depict portions of the aerosol collector that form no part of the claimed design.-
公开(公告)号:US11747238B2
公开(公告)日:2023-09-05
申请号:US17209434
申请日:2021-03-23
Applicant: InnovaPrep LLC
Inventor: Andrew Edward Page , Zachary A. Packingham , David Scott Alburty , Alec D. Adolphson
CPC classification number: G01N1/10 , G01N1/14 , G01N1/34 , G01N1/4077 , G01N2001/4088
Abstract: Highly efficient and rapid filtration-based concentration devices, systems and methods are disclosed with sample fluidic lines and a filter packaged in a disposable tip which concentrate biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. The concentrate is then dispensed from the disposable tip in a set volume of elution fluid. Suspended biological particles include such materials as proteins/toxins, viruses, DNA, and/or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect. A single-use pipette tip includes fluid ports for aspirating the sample and connecting to a concentrating unit.
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