公开(公告)号：US11518983B1

公开(公告)日：2022-12-06

申请号：US17824118

申请日：2022-05-25

Applicant: INVIZYNE TECHNOLOGIES, INC.

Inventor： Tyler P. Korman

IPC: C12N9/10 ,  C12P7/42 ,  C12N15/82 ,  C12N15/52

Abstract: The present disclosure relates to recombinant prenyltransferase enzymes with increased thermostability and activity and the use of these enzymes in compositions and methods for biosynthesis involving prenylation reactions, including compositions and methods for the preparation of cannabinoids.

公开(公告)号：US20240076699A1

公开(公告)日：2024-03-07

申请号：US18227719

申请日：2023-07-28

Applicant: Invizyne Technologies, Inc.

Inventor： Tyler P. Korman ,  Bastian Vogeli ,  Andrew Lingard ,  Mohammad Hayat

IPC: C12P7/22 ,  C12N9/10 ,  C12N9/12

CPC classification number: C12P7/22 ,  C12N9/1085 ,  C12N9/1205 ,  C12Y205/0101 ,  C12Y207/0105 ,  C12Y207/01127

Abstract: Systems and methods for prenylation and recombinant pathways for the production of compounds, cannabinoids, cannabinoid precursors, and other prenylated chemicals in a cell free system. The present invention further includes enzymes and recombinant microorganisms that catalyze the reaction. The compounds, cannabinoids, cannabinoid precursors, and other prenylated chemicals are operable to be substituted with at least one deuterium, at least one tritium, at least one halogen, at least one hydroxyl group, and/or at least one additional isotope.

公开(公告)号：US20250043319A1

公开(公告)日：2025-02-06

申请号：US18918626

申请日：2024-10-17

Applicant: Invizyne Technologies, Inc.

Inventor： John BILLINGSLEY ,  Tyler P. KORMAN ,  Mohammad HAYAT

IPC: C12P7/22 ,  C12N9/10 ,  C12P17/06

Abstract: The present disclosure relates to compositions comprising cyclolavandulyl derivatives of aromatic compounds, such as cannabinoids, flavonoids, and alkaloids, and methods for preparing and using the compositions.

公开(公告)号：US12084689B2

公开(公告)日：2024-09-10

申请号：US17934560

申请日：2022-09-22

Applicant: INVIZYNE TECHNOLOGIES, INC.

Inventor： Tyler P. Korman

IPC: C12N9/10 ,  C12N15/52 ,  C12N15/82 ,  C12P7/42

CPC classification number: C12N9/1085 ,  C12N15/52 ,  C12N15/8243 ,  C12P7/42 ,  C12Y203/01206

Abstract: The present disclosure relates to recombinant prenyltransferase enzymes with increased thermostability and activity and the use of these enzymes in compositions and methods for biosynthesis involving prenylation reactions, including compositions and methods for the preparation of cannabinoids.

公开(公告)号：US20230098978A1

公开(公告)日：2023-03-30

申请号：US17934560

申请日：2022-09-22

Applicant: INVIZYNE TECHNOLOGIES, INC.

Inventor： Tyler P. KORMAN

IPC: C12N9/10 ,  C12N15/52 ,  C12N15/82 ,  C12P7/42

Abstract: The present disclosure relates to recombinant prenyltransferase enzymes with increased thermostability and activity and the use of these enzymes in compositions and methods for biosynthesis involving prenylation reactions, including compositions and methods for the preparation of cannabinoids.

公开(公告)号：US20220403349A1

公开(公告)日：2022-12-22

申请号：US17824118

申请日：2022-05-25

Applicant: INVIZYNE TECHNOLOGIES, INC.

Inventor： Tyler P. KORMAN

IPC: C12N9/10 ,  C12P7/42 ,  C12N15/52 ,  C12N15/82

Abstract: The present disclosure relates to recombinant prenyltransferase enzymes with increased thermostability and activity and the use of these enzymes in compositions and methods for biosynthesis involving prenylation reactions, including compositions and methods for the preparation of cannabinoids.