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1.发明授权Compositions for inhibiting virus entry and promoting virolysis, and methods thereof 有权用于抑制病毒进入和促进病毒分解的组合物及其方法公开(公告)号：US09114107B2
公开(公告)日：2015-08-25
申请号：US13876876
申请日：2011-10-05
Applicant: Irwin Chaiken , Arangassery Rosemary Bastian , Kantharaju , Constantinos Papathomas
Inventor： Irwin Chaiken , Elisabeth S. Papazoglou , Arangassery Rosemary Bastian , Kantharaju
IPC: A61K38/10 , C07K7/08 , A61P31/14 , A61K38/08 , A61K45/06 , C07K7/02 , A61K47/48 , A61K31/555 , C07D211/58 , C07D471/04
CPC classification number: A61K38/10 , A61K31/555 , A61K38/08 , A61K45/06 , A61K47/6923 , C07D211/58 , C07D471/04 , C07K7/02 , C07K7/08 , Y02A50/385 , A61K2300/00
Abstract: The present invention includes a composition comprising a gold nanoparticle complexed with a cysteine-containing compound. The invention also includes the method of preparing a composition comprising a gold nanoparticle complexed with a cysteine-containing compound. The invention further includes a method of causing virolysis of a virus using the compositions described therein. The invention further includes a method of inhibiting virus entry using the compositions described therein.
Abstract translation: 本发明包括包含与含半胱氨酸的化合物络合的金纳米颗粒的组合物。 本发明还包括制备包含与含半胱氨酸的化合物络合的金纳米颗粒的组合物的方法。 本发明还包括使用其中所述的组合物对病毒进行病毒溶解的方法。 本发明还包括使用其中所述的组合物抑制病毒进入的方法。
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公开(公告)号：US20090191630A1
公开(公告)日：2009-07-30
申请号：US12409285
申请日：2009-03-23
Applicant: Gopi Hosahudya , Irwin Chaiken
Inventor： Gopi Hosahudya , Irwin Chaiken
Abstract: Compounds, which inhibit the binding of gp120 to CD4 as well as 17b and methods for their use in inhibiting the HIV fusion process, are provided.
Abstract translation: 提供抑制gp120与CD4以及17b结合的化合物及其用于抑制HIV融合过程的方法。
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公开(公告)号：US07556808B2
公开(公告)日：2009-07-07
申请号：US11305401
申请日：2005-12-16
Applicant: Gopi Hosahudya , Irwin Chaiken
Inventor： Gopi Hosahudya , Irwin Chaiken
IPC: A61K39/00 , A61K39/21 , A61K38/00 , A61K39/385 , C12N33/53
Abstract: Compounds, which inhibit the binding of gp120 to CD4 as well as 17b and methods for their use in inhibiting the HIV fusion process, are provided.
Abstract translation: 提供抑制gp120与CD4以及17b结合的化合物及其用于抑制HIV融合过程的方法。
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公开(公告)号：US08092805B2
公开(公告)日：2012-01-10
申请号：US12638725
申请日：2009-12-15
Applicant: Hosahudya Gopi , Irwin Chaiken
Inventor： Hosahudya Gopi , Irwin Chaiken
Abstract: Compounds, which inhibit the binding of gp120 to CD4 as well as 17b and methods for their use in inhibiting the HIV fusion process, are provided.
Abstract translation: 提供抑制gp120与CD4以及17b结合的化合物及其用于抑制HIV融合过程的方法。
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Patent Agency Ranking
公开(公告)号：US20100099188A1
公开(公告)日：2010-04-22
申请号：US12638725
申请日：2009-12-15
Applicant: Hosahudya Gopi , Irwin Chaiken
Inventor： Hosahudya Gopi , Irwin Chaiken
IPC: C12N5/02 , G01N33/566
Abstract: Compounds, which inhibit the binding of gp120 to CD4 as well as 17b and methods for their use in inhibiting the HIV fusion process, are provided.
Abstract translation: 提供抑制gp120与CD4以及17b结合的化合物及其用于抑制HIV融合过程的方法。
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公开(公告)号：US20060029594A1
公开(公告)日：2006-02-09
申请号：US11076395
申请日：2005-10-20
Applicant: Robert Ames , Edward Appelbaum , Irwin Chaiken , Richard Cook , Mitchell Gross , Stephen Holmes , Lynette McMillan , Timothy Theisen
Inventor： Robert Ames , Edward Appelbaum , Irwin Chaiken , Richard Cook , Mitchell Gross , Stephen Holmes , Lynette McMillan , Timothy Theisen
IPC: A61K39/395 , C12N5/06 , C07K16/44
CPC classification number: C07K16/244 , A61K2039/505 , C07K2317/24 , C07K2317/55 , C07K2319/00
Abstract: Chimeric, humanized and other IL-5 mAbs, derived from high affinity neutralizing mAbs, pharmaceutical compositions containing same, methods of treatment and diagnostics are provided.
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7.发明申请Novel Compositions for Inhibiting Virus Entry and Promoting Virolysis, and Methods Thereof 有权用于抑制病毒进入和促进病毒分解的新型组合物及其方法公开(公告)号：US20140050793A1
公开(公告)日：2014-02-20
申请号：US13876876
申请日：2011-10-05
Applicant: Irwin Chaiken , Arangassery Rosemary Bastian , Kantharaju
Inventor： Irwin Chaiken , Elisabeth S. Papazoglou , Arangassery Rosemary Bastian , Kantharaju
IPC: A61K38/10 , A61K31/555 , C07D211/58 , C07D471/04 , C07K7/08 , A61K45/06
CPC classification number: A61K38/10 , A61K31/555 , A61K38/08 , A61K45/06 , A61K47/6923 , C07D211/58 , C07D471/04 , C07K7/02 , C07K7/08 , Y02A50/385 , A61K2300/00
Abstract: The present invention includes a composition comprising a gold nanoparticle complexed with a cysteine-containing peptide. The invention also includes the method of preparing a composition comprising a gold nanoparticle complexed with a cysteine-containing peptide. The invention further includes a method of causing virolysis of a virus using the compositions described therein.
Abstract translation: 本发明包括包含与含半胱氨酸的肽复合的金纳米颗粒的组合物。 本发明还包括制备包含与含半胱氨酸的肽复合的金纳米颗粒的组合物的方法。 本发明还包括使用其中所述的组合物对病毒进行病毒溶解的方法。
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公开(公告)号：US20060135746A1
公开(公告)日：2006-06-22
申请号：US11305401
申请日：2005-12-16
Applicant: Gopi Hosahudya , Irwin Chaiken
Inventor： Gopi Hosahudya , Irwin Chaiken
IPC: A61K31/70 , C07K14/00 , A01N43/04 , C07K16/00 , A61K38/00 , C07K17/00 , C07K2/00 , C07K4/00 , C07K5/00 , C07K7/00
Abstract: Compounds, which inhibit the binding of gp120 to CD4 as well as 17b and methods for their use in inhibiting the HIV fusion process, are provided.
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公开(公告)号：US07655464B2
公开(公告)日：2010-02-02
申请号：US12409285
申请日：2009-03-23
Applicant: Gopi Hosahudya , Irwin Chaiken
Inventor： Gopi Hosahudya , Irwin Chaiken
Abstract: Compounds, which inhibit the binding of gp120 to CD4 as well as 17b and methods for their use in inhibiting the HIV fusion process, are provided.
Abstract translation: 提供抑制gp120与CD4以及17b结合的化合物及其用于抑制HIV融合过程的方法。
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