公开(公告)号：US20080106737A1

公开(公告)日：2008-05-08

申请号：US12005396

申请日：2007-12-27

Applicant: Amnon Weichselbaum ,  Jaime De La Zerda ,  Issakhar Regev

Inventor： Amnon Weichselbaum ,  Jaime De La Zerda ,  Issakhar Regev

IPC: G01N21/00 ,  G01N1/10

CPC classification number: G01N21/51 ,  G01N21/0303 ,  G01N33/493 ,  G01N2021/0382 ,  G01N2021/4769 ,  G01N2021/479 ,  G01N2021/513 ,  G01N2201/064

Abstract: System and method for detecting and counting bacteria suspended in a biological fluid by means of light scattering measurements is provided. In accordance with the method of the invention the level of signal to noise of the measured intensities of light scattered by a sample of the biological fluid is significantly enhanced for forwardly scattered light within a range of scattering angles which are smaller compared to a predefined maximal scattering angle. The system of the invention includes a cuvette adapted to contain a sample of the biological fluid whose sidewalls and windows are suitably constructed and arranged to significantly reduce the level of reflected light obscuring the scattering patterns measured within the range of scattering angles considered.

Abstract translation: 提供了通过光散射测量来检测和计数悬浮在生物流体中的细菌的系统和方法。 根据本发明的方法，在与预定的最大散射相比较小的散射角范围内的向前散射光显着增强了由生物流体样本散射的光的测量强度的信噪比水平 角度。 本发明的系统包括适于容纳生物流体的样本的比色皿，其侧壁和窗口被适当地构造和布置，以显着降低反射光的水平，掩盖了在所考虑的散射角度范围内测量的散射图案。

公开(公告)号：US20100277734A1

公开(公告)日：2010-11-04

申请号：US12810838

申请日：2008-12-24

Applicant: Amnon Weichselbaum ,  Jaime De La Zerda ,  Issakhar Regev

Inventor： Amnon Weichselbaum ,  Jaime De La Zerda ,  Issakhar Regev

IPC: G01N21/00

CPC classification number: G01N21/51 ,  G01N21/0303 ,  G01N33/493 ,  G01N2021/0382 ,  G01N2021/4769 ,  G01N2021/479 ,  G01N2021/513 ,  G01N2201/064

Abstract: System and method for detecting and counting bacteria suspended in a biological fluid by means of light scattering measurements is provided. In accordance with the method of the invention the level of signal to noise of the measured intensities of light scattered by a sample of the biological fluid is significantly enhanced for forwardly scattered light within a range of scattering angles which are smaller compared to a predefined maximal scattering angle. The system of the invention includes a cuvette adapted to contain a sample of the biological fluid whose sidewalls and windows are suitably constructed and arranged to significantly reduce the level of reflected light obscuring the scattering patterns measured within the range of scattering angles considered.

Abstract translation: 提供了通过光散射测量来检测和计数悬浮在生物流体中的细菌的系统和方法。 根据本发明的方法，在与预定的最大散射相比较小的散射角范围内的向前散射光显着增强了由生物流体样本散射的光的测量强度的信噪比水平 角度。 本发明的系统包括适于容纳生物流体的样本的比色皿，其侧壁和窗口被适当地构造和布置，以显着降低反射光的水平，遮蔽在所考虑的散射角度范围内测量的散射图案。

公开(公告)号：US07961311B2

公开(公告)日：2011-06-14

申请号：US12810838

申请日：2008-12-24

Applicant: Amnon Weichselbaum ,  Jaime De La Zerda ,  Issakhar Regev

Inventor： Amnon Weichselbaum ,  Jaime De La Zerda ,  Issakhar Regev

IPC: G01N21/01

CPC classification number: G01N21/51 ,  G01N21/0303 ,  G01N33/493 ,  G01N2021/0382 ,  G01N2021/4769 ,  G01N2021/479 ,  G01N2021/513 ,  G01N2201/064

Abstract: System and method for detecting and counting bacteria suspended in a biological fluid by means of light scattering measurements is provided. In accordance with the method of the invention the level of signal to noise of the measured intensities of light scattered by a sample of the biological fluid is significantly enhanced for forwardly scattered light within a range of scattering angles which are smaller compared to a predefined maximal scattering angle. The system of the invention includes a cuvette adapted to contain a sample of the biological fluid whose sidewalls and windows are suitably constructed and arranged to significantly reduce the level of reflected light obscuring the scattering patterns measured within the range of scattering angles considered.

Abstract translation: 提供了通过光散射测量来检测和计数悬浮在生物流体中的细菌的系统和方法。 根据本发明的方法，在与预定的最大散射相比较小的散射角范围内的向前散射光显着增强了由生物流体样本散射的光的测量强度的信噪比水平 角度。 本发明的系统包括适于容纳生物流体的样本的比色皿，其侧壁和窗口被适当地构造和布置，以显着降低反射光的水平，遮蔽在所考虑的散射角度范围内测量的散射图案。