公开(公告)号：US11686678B2

公开(公告)日：2023-06-27

申请号：US17152754

申请日：2021-01-19

申请人： Wyatt Technology Corporation

发明人： David Rahmlow ,  Matthew Greenstreet ,  Shiladitya Sen

IPC分类号： G01N21/53 ,  G01N15/14 ,  G01N21/39 ,  G01N21/05 ,  G01N30/74 ,  G01N15/02 ,  G01N21/51 ,  G01N21/47

CPC分类号： G01N21/532 ,  G01N15/0211 ,  G01N15/1404 ,  G01N15/1434 ,  G01N21/05 ,  G01N21/39 ,  G01N21/53 ,  G01N30/74 ,  G01N2015/1452 ,  G01N2021/058 ,  G01N2021/4711 ,  G01N2021/513 ,  G01N2030/746

摘要： A new liquid flow cell assembly for light scattering measurements is disclosed which utilized a floating manifold system. The assembly operates with minimal stacked tolerances by aligning the cell to the windows within a manifold and independently aligning the cell to the read head directly. This configuration enables the ability to replace the flow cell or the flow cell/manifold assembly within a light scattering instrument without the need to realign the flow through elements with the light scattering illumination source while still maintaining reproducible, quality data. Some embodiments employ wide bore cells which enable the measurement of process analytic technology (PAT) including online monitoring of reactions.

公开(公告)号：US10006857B2

公开(公告)日：2018-06-26

申请号：US15005321

申请日：2016-01-25

申请人： BacterioScan LTD

发明人： Dana A. Marshall ,  Dan Vadim Regelman

IPC分类号： G01N21/51 ,  G01N21/03

CPC分类号： G01N21/51 ,  G01N21/0303 ,  G01N2021/513 ,  G01N2201/0231 ,  G01N2201/0415

摘要： An instrument determines a concentration of bacteria in a plurality of fluid samples, and comprises a housing, a rotatable platform, a plurality of fluid containers, a light source, a sensor, and a motor. The rotatable platform is within the housing. The fluid containers are located on the rotatable platform. Each fluid container holds a corresponding one of the plurality of fluid samples, and has an input window and an output window. The light source provides an input beam for transmission into the input windows of the fluid containers and through the corresponding fluid samples. The input beam creates a forward-scatter signal associated with the concentration of bacteria. The motor rotates the rotatable platform so that the input beam sequentially passes through each fluid sample. A sensor within the housing detects the forward-scatter signal exiting from the output window associated with the fluid sample receiving the input beam.

公开(公告)号：US09823190B2

公开(公告)日：2017-11-21

申请号：US14859780

申请日：2015-09-21

申请人： RION CO., LTD.

发明人： Takashi Minakami ,  Masaki Shimmura ,  Tomonobu Matsuda

IPC分类号： G01N15/14 ,  G01N21/53 ,  G01N15/00 ,  G01N21/03 ,  G01N21/51

CPC分类号： G01N21/53 ,  G01N15/1459 ,  G01N2015/0053 ,  G01N2015/1486 ,  G01N2021/0392 ,  G01N2021/513

摘要： A particle counter for chemical solution in this disclosure uses a flow cell through which a chemical solution including particles flows, a laser light, and a light-receiving element array. Scattered light from the particles passing through a detection region on an optical path of the laser light in the flow cell is condensed to the light-receiving element array. The laser light in the center of the detection region has an energy density of 3×108 mW/cm2 or more. Each of plural light-receiving elements (a) is larger in length and width than a spot diameter of the scattered light, and (b) receives the scattered light from a region with a size of 760 μm2 or less included in the detection region. The signal processing unit counts the particles passing through the detection region by use of a threshold corresponding to the smallest measurable particle size of 0.03 μm.

公开(公告)号：US20170307526A1

公开(公告)日：2017-10-26

申请号：US15517679

申请日：2014-11-25

申请人： Halliburton Energy Services, Inc.

发明人： Rui Shen ,  Timothy N. Harvey ,  Dale E. Jamison ,  Cato Russell McDaniel

IPC分类号： G01N21/51 ,  G01V8/12 ,  G01N15/08 ,  E21B41/00 ,  G01N21/47

CPC分类号： G01N21/51 ,  E21B41/00 ,  E21B49/08 ,  E21B2049/085 ,  G01N15/0806 ,  G01N2015/084 ,  G01N2021/4709 ,  G01N2021/513 ,  G01V8/12

摘要： Turbidity measurement systems and methods of using the same are described. A turbidity measurement system comprise a vessel configured to hold a wellbore fluid, wherein a permeable obstruction to flow is positioned in the vessel; a light source positioned to direct light at the vessel; a light detector positioned to measure light intensity of light emitted by the light source and passing through the vessel; and a backscatter detector positioned to measure the light intensity of reflected light emitted from the light source.

公开(公告)号：US09784669B2

公开(公告)日：2017-10-10

申请号：US14951504

申请日：2015-11-25

申请人： HACH LANGE GMBH

发明人： Manfred Battefeld ,  Bas De Heij ,  Hans-Joachim Kumpch ,  Andreas Mitreiter ,  Andreas Golitz

IPC分类号： G01N1/10 ,  G01N21/03 ,  G01N21/51 ,  G01N21/49

CPC分类号： G01N21/0303 ,  G01N21/49 ,  G01N21/51 ,  G01N2021/513 ,  G01N2201/064 ,  G01N2201/068

摘要： A nephelometric turbidimeter with a cylindrical turbidimeter vial. The cylindrical turbidimeter vial includes a transparent vial body and a circular optical shielding configured to optically block an inside from an outside of the turbidimeter vial. The vial body comprises a transparent and flat bottom inlet window, and a transparent vial cylinder body. The vial cylinder body comprises a circular outlet window. The optical shielding is arranged axially above the outlet window of the vial cylinder body, over a part of an axial length of the vial cylinder body, and axially adjacent to a non-shielded part of the vial cylinder body which serves as the outlet window.

公开(公告)号：US20170203296A1

公开(公告)日：2017-07-20

申请号：US15444906

申请日：2017-02-28

申请人： Sony Corporation

发明人： Tomomi YUKUMOTO ,  Takeshi YAMASAKI ,  Shoji AKIYAMA ,  Yuji AKIYAMA

IPC分类号： B01L3/00 ,  G01N21/51 ,  B32B27/08 ,  B32B3/30 ,  B32B3/08

CPC分类号： B32B3/30 ,  B01L3/502707 ,  B01L3/502715 ,  B01L2200/0636 ,  B01L2200/0689 ,  B01L2200/12 ,  B01L2300/0645 ,  B01L2300/0654 ,  B01L2300/0816 ,  B01L2300/0838 ,  B01L2300/0877 ,  B01L2300/0887 ,  B32B3/08 ,  B32B3/266 ,  B32B27/08 ,  B32B2307/412 ,  G01N21/51 ,  G01N21/645 ,  G01N2021/513 ,  G01N2021/6482 ,  G01N2201/06113 ,  Y10T428/24612

摘要： There is provided a microchip including at least two substrates each comprising a thermoplastic resin, and at least one member comprising a material having a heat distortion temperature higher than a heat distortion temperature of the thermoplastic resin, the at least one member including at least one engagement end including a protrusion extending between the at least two substrates, wherein the at least one member is fixed to the at least two substrates by the protrusion being held between the at least two substrates by at least one wall surface that is thermally deformed by thermocompression.

公开(公告)号：US09579648B2

公开(公告)日：2017-02-28

申请号：US14562304

申请日：2014-12-05

申请人： BacterioScan Inc.

发明人： Dana A. Marshall ,  Theodore S. McMinn ,  Dan Vadim Regelman

IPC分类号： B01L3/00 ,  G01N21/51

CPC分类号： B01L3/50255 ,  B01L3/50853 ,  B01L2200/0684 ,  B01L2300/022 ,  B01L2300/043 ,  B01L2300/044 ,  B01L2300/045 ,  B01L2300/0654 ,  B01L2300/0672 ,  B01L2300/0681 ,  B01L2400/0683 ,  G01N21/51 ,  G01N2021/513

摘要： The present invention is a cuvette assembly for use in optically measuring at least one characteristic of particles within a plurality of liquid samples. The cuvette assembly comprises a main body having internal walls and external walls, and a plurality of cuvettes within the main body at least partially being defined by the internal walls. Each of the plurality of cuvettes has a liquid-input chamber for receiving a respective one of the plurality of liquid samples, a filter, and an optical chamber for receiving a respective filtered liquid sample caused by passing the respective one of the plurality of liquid samples through the filter. Each of the optical chambers includes an entry window for allowing transmission of an input light beam through the filtered liquid sample and an exit window for transmitting a forward scatter signal caused by the particles within the filtered liquid sample.

摘要翻译： 本发明是一种用于光学测量多个液体样品中的颗粒的至少一种特性的比色皿组件。 所述比色杯组件包括具有内壁和外壁的主体，并且所述主体内的多个比色皿至少部分地由所述内壁限定。 多个试管中的每一个具有用于接收多个液体样品中的相应一个液体样品的液体输入室，用于接收由多个液体样品中的相应一个液体样品引起的各自过滤液体样品的光学室 通过过滤器。 每个光学室包括入口窗口，用于允许输入光束通过过滤的液体样品和用于传输由过滤液体样品内的颗粒引起的前向散射信号的出射窗口。

公开(公告)号：US09410882B2

公开(公告)日：2016-08-09

申请号：US14890428

申请日：2013-05-13

申请人： HACH LANGE GMBH

发明人： Barbara Haase ,  Manfred Battefeld ,  Andreas Mitreiter ,  Michael Kussmann ,  Bas De Heij ,  Clemens Hanschke ,  Wayne Perdue

IPC分类号： G01N21/00 ,  G01N21/51

CPC分类号： G01N21/51 ,  G01N21/53 ,  G01N2021/513 ,  G01N2201/0633 ,  G01N2201/0636

摘要： A turbidimeter for measuring a turbidity of a liquid sample in a sample cuvette includes a cuvette receiving device configured to position the sample cuvette in a defined cuvette position, a light source configured to generate a parallel light beam in the sample cuvette, an annular 45° collecting mirror configured to surround the sample cuvette, a scattering body arranged concentric to the annular 45° collecting mirror, a scattering light detector arranged to receive light scattered by the scattering body, and an annular 45° concentration mirror arranged coaxially to the annular 45° collecting mirror and optically opposite to the annular 45° collecting mirror. The annular 45° collecting mirror is arranged concentric to the light beam. The annular 45° concentration mirror is configured to surround the scattering body.

摘要翻译： 用于测量样品比色皿中的液体样品的浊度的浊度计包括配置成将样品比色皿定位在规定的比色杯位置的比色皿接收装置，被配置为在样品比色皿中产生平行光束的光源，环形45° 收集镜，被配置为围绕样品比色皿，与环形45°收集镜同心设置的散射体，布置成接收由散射体散射的光的散射光检测器和与环状45°同轴设置的环形45°浓度反射镜 收集反射镜并与环形45°收集镜光学相对。 环形45°收集镜与光束同心设置。 环形45°浓度反射镜被配置为围绕散射体。

公开(公告)号：US09404917B1

公开(公告)日：2016-08-02

申请号：US14950323

申请日：2015-11-24

申请人： Avishay Bransky ,  Liron Shlomo

发明人： Avishay Bransky ,  Liron Shlomo

IPC分类号： G01N1/00 ,  G01N33/52 ,  G01N33/53 ,  G01N35/04

CPC分类号： B01L3/50273 ,  B01L3/5027 ,  B01L3/502715 ,  B01L2200/0684 ,  B01L2300/0609 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/0883 ,  B01L2400/0406 ,  B01L2400/0478 ,  B01L2400/0481 ,  B01L2400/0493 ,  G01N21/05 ,  G01N21/51 ,  G01N33/521 ,  G01N33/5302 ,  G01N35/00029 ,  G01N35/04 ,  G01N2021/058 ,  G01N2021/513 ,  G01N2035/00039

摘要： A fluid analysis system may include a stage configured to receive a sample holder including a fluid sample to be analyzed. The fluid analysis system may also include a fluid analyzer configured to monitor at least one characteristic of the fluid sample to be analyzed; and an inclined rail; wherein the stage is configured to move along the inclined rail to cause the sample holder to move with a first component of motion along an analysis axis of the fluid analyzer and simultaneously with a second component of motion orthogonal to the analysis axis of the fluid analyzer, wherein the first component of motion affects a focus of the fluid analyzer relative to at least one constituent of the fluid sample to be analyzed.

公开(公告)号：US09377481B1

公开(公告)日：2016-06-28

申请号：US13134959

申请日：2011-06-16

申请人： Paul S Greenberg ,  David G Fischer

发明人： Paul S Greenberg ,  David G Fischer

IPC分类号： G01N15/02 ,  G01P5/00 ,  G01N21/51

CPC分类号： G01P5/001 ,  G01N15/0205 ,  G01N15/06 ,  G01N2015/0693 ,  G01N2021/513

摘要： Methods, detectors and systems detect particles and/or measure particle properties. According to one embodiment, a detector for detecting particles comprises: a sensor for receiving radiation scattered by an ensemble of particles; and a processor for determining a physical parameter for the detector, or an optimal detection angle or a bound for an optimal detection angle, for measuring at least one moment or integrated moment of the ensemble of particles, the physical parameter, or detection angle, or detection angle bound being determined based on one or more of properties (a) and/or (b) and/or (c) and/or (d) or ranges for one or more of properties (a) and/or (b) and/or (c) and/or (d), wherein (a)-(d) are the following: (a) is a wavelength of light incident on the particles, (b) is a count median diameter or other characteristic size parameter of the particle size distribution, (c) is a standard deviation or other characteristic width parameter of the particle size distribution, and (d) is a refractive index of particles.

摘要翻译： 方法，检测器和系统检测颗粒和/或测量颗粒性质。 根据一个实施例，用于检测颗粒的检测器包括：用于接收由颗粒集合散射的辐射的传感器; 以及用于确定检测器的物理参数或最佳检测角度或最佳检测角度的边界的处理器，用于测量粒子集合，物理参数或检测角度的至少一个时刻或集成时刻，或 基于属性（a）和/或（b）和/或（c）和/或（d）或属性（a）和/或（b）中的一个或多个）的一个或多个确定检测角度， 和（或）（c）和/或（d），其中（a） - （d）如下：（a）是入射到颗粒上的光的波长，（b）是计数中值直径或其他特征尺寸 粒度分布的参数，（c）是粒度分布的标准偏差或其他特征宽度参数，（d）是粒子的折射率。