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公开(公告)号：USD681811S1
公开(公告)日：2013-05-07
申请号：US29403322
申请日：2011-10-04
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公开(公告)号：US08152755B1
公开(公告)日：2012-04-10
申请号：US12731019
申请日：2010-03-24
CPC分类号： A61M25/00 , A61M5/178 , A61M25/0026 , A61M25/007 , A61M2206/20
摘要： A catheter for delivering a therapeutic agent to a target site of a human or animal subject can include a substantially flexible and biocompatible catheter body having a proximal end and a distal end. An eductor can be located at the distal end of the catheter body, and a first lumen within the catheter body for housing the therapeutic agent can be in fluid communication with the eductor. A second lumen, also in fluid communication with the first lumen, can extend from the proximal end of the catheter body towards the eductor and can have an output port at the distal end of the catheter body. The eductor can be operable to induce the therapeutic agent to flow from the first lumen out of the output port in response to fluid flowing through the second lumen.
摘要翻译： 用于将治疗剂递送到人或动物受试者的靶位点的导管可以包括具有近端和远端的基本上柔性且生物相容的导管主体。 喷射器可以位于导管主体的远端，并且用于容纳治疗剂的导管主体内的第一腔可以与喷射器流体连通。 也与第一腔流体连通的第二腔可以从导管主体的近端延伸到喷射器，并且可以在导管主体的远端具有输出端口。 喷射器可操作以响应于流体流过第二腔而致使治疗剂从第一腔流出输出端口。
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3.发明申请SCLERAL PROSTHESIS FOR TREATING PRESBYOPIA AND OTHER EYE DISORDERS AND RELATED DEVICES AND METHODS 有权治疗前列腺炎和其他眼病的SCLERAL PROSTHESIS及相关设备和方法公开(公告)号：US20110077735A1
公开(公告)日：2011-03-31
申请号：US12960917
申请日：2010-12-06
申请人： Jack C. Griffis, III
发明人： Jack C. Griffis, III
IPC分类号： A61F2/16
CPC分类号： A61F2/147 , A61F2/148 , A61F2210/0023
摘要： One example scleral prosthesis includes a first free end and a second free end, each wider than a middle portion of the scleral prosthesis. Multiple first portions form the first end of the scleral prosthesis. The first portions are separated along at least half of a length of the scleral prosthesis. Multiple second portions may form the second end of the scleral prosthesis, and the second portions may be separated along less than a quarter of the length of the scleral prosthesis. An implantation device can be used to facilitate implantation of a scleral prosthesis. The implantation device includes a first end portion configured to be inserted into a scleral tunnel of an eye. The implantation device also includes a second end portion configured to receive the scleral prosthesis. A rod with a tapered and rounded end can be partially inserted into the first end portion of the implantation device.
摘要翻译： 一个例子是巩膜假体包括第一自由端和第二自由端，每个宽度大于巩膜假体的中间部分。 多个第一部分形成巩膜假体的第一端。 第一部分沿巩膜假体长度的至少一半分开。 多个第二部分可以形成巩膜假体的第二端，并且第二部分可以沿着巩膜假体的长度的小于四分之一分开。 可以使用植入装置来促进巩膜假体的植入。 植入装置包括构造成插入到眼睛的巩膜隧道中的第一端部。 植入装置还包括构造成接收巩膜假体的第二端部。 具有锥形和圆形端的杆可以部分地插入植入装置的第一端部。
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4.发明申请Method and system for maintaining aseptic conditions in the storage of biologics 审中-公开维持生物制品储存无菌条件的方法和系统公开(公告)号：US20110054436A1
公开(公告)日：2011-03-03
申请号：US12806541
申请日：2010-08-16
申请人： Jack C. Griffis, III , Minh Vo
发明人： Jack C. Griffis, III , Minh Vo
IPC分类号： A61J1/22
CPC分类号： A61J1/2096 , A61J1/2037 , A61J9/00
摘要： Technologies are generally described for the storage of biologics and other fluid materials while maintaining aseptic conditions. A system may include a storage body providing a reservoir for containing the materials. A cap may couple to the storage body forming a fluid-tight seal. A port may be provided for transferring the materials. A seal, or valve, may be provided within the port. The seal may be configured to close off the reservoir unless acted upon to release the materials through the port. A movable member may make up part of the storage body. The movable member may be configured to change a reservoir volume of the storage body in response to changes in a volume of the materials. The reservoir may become smaller as the materials are released. Multi-dose volumes of fluid materials may be stored for repeated access with reduced risk of contamination and reduction in shelf life.
摘要翻译： 技术通常被描述为用于储存生物制剂和其它流体材料，同时保持无菌条件。 系统可以包括提供用于容纳材料的储存器的存储体。 盖可以连接到存储体，形成流体密封。 可以提供用于传送材料的端口。 密封件或阀门可以在端口内提供。 密封件可以被配置为关闭储存器，除非作用于通过端口释放材料。 可移动部件可以构成存储体的一部分。 可移动构件可以被配置为响应于材料体积的变化而改变存储体的储存器容积。 当材料被释放时，储存器可能变小。 多剂量的流体材料可以被存储以用于重复进入，降低污染的风险和降低保质期。
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5.发明申请SCLERAL PROSTHESIS HAVING CROSSBARS FOR TREATING PRESBYOPIA AND OTHER EYE DISORDERS 有权治疗前列腺炎和其他眼睛疾病的十字架前列腺切除术公开(公告)号：US20090099654A1
公开(公告)日：2009-04-16
申请号：US12183237
申请日：2008-07-31
申请人： Jack C. Griffis, III , Mark A. Cox , Douglas C. Williamson , Peter J. Richardson , Barrie D. Soloway
发明人： Jack C. Griffis, III , Mark A. Cox , Douglas C. Williamson , Peter J. Richardson , Barrie D. Soloway
IPC分类号： A61F2/14
摘要： A scleral prosthesis includes a prosthesis body having first and second side surfaces and a cavity extending through the prosthesis body from the first side surface to the second side surface. The scleral prosthesis also includes a crossbar configured to be inserted into the cavity, where the crossbar is wider than the prosthesis body. The cavity could define a narrower central opening and wider end openings, and the crossbar could have a narrower central portion and wider end portions. Also, the prosthesis body could include multiple cavities, and the scleral prosthesis could include multiple crossbars configured to be inserted into the multiple cavities. Each of the cavities could be located proximate to an end of the prosthesis body. The crossbar could be substantially straight with a cylindrical cross section.
摘要翻译： 巩膜假体包括具有第一和第二侧表面的假体，以及从第一侧表面延伸穿过假体的第二侧表面的腔。 巩膜假体还包括构造成插入空腔中的横杆，其中横杆比修复体更宽。 空腔可以限定较窄的中心开口和较宽的端部开口，并且横杆可具有较窄的中心部分和较宽的端部部分。 此外，假体可以包括多个腔，并且巩膜假体可以包括构造成插入到多个腔中的多个十字形杆。 每个空腔可以位于邻近假体的端部附近。 横杆可以是基本上直的圆柱形横截面。
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公开(公告)号：US07018402B2
公开(公告)日：2006-03-28
申请号：US10093715
申请日：2002-03-07
IPC分类号： A61F2/06
摘要： Intravascular devices and methods are provided for forming a vascular graft by axially distending a blood vessel to induce growth. These devices advantageously can be implanted via a catheter, thereby eliminating the need for a more invasive implantation procedure when the stretching is to be done in vivo. Preferably, the device for axially distending a blood vessel to induce growth of the vessel includes an intravascular stretching mechanism attachable directly to an interior lumen portion of the blood vessel, and a means for operating the stretching mechanism to cause the vessel to distend axially. The stretching mechanism can include a pair of wires or stents that engage the blood vessel wall. Components of the stretching mechanism can include a shape memory material.
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公开(公告)号：US08535291B1
公开(公告)日：2013-09-17
申请号：US13466041
申请日：2012-05-07
IPC分类号： A61M31/00
CPC分类号： A61B17/3478 , A61B2017/00243 , A61B2017/00247 , A61B2034/102 , G06F19/00
摘要： A medical practitioner can specify certain parameters for a procedure that involves delivering a therapeutic agent, while leaving other parameters open. The therapeutic agent can be sensitive to biomechanical forces (or other influences) associated with delivery. The procedure can involve regenerative medicine, for example delivering progenitor or stem cells to a diseased heart using a catheter, whereby unbridled transport in the catheter may compromise efficacy. The open parameters can influence efficacy of the agent and thus therapeutic outcome. A computer-based system can apply stored information, such as from databases, to narrow the possible values of the open parameters. From the narrowed possibilities, an optimization routine can determine suitable or optimized values for the open parameters. The determined values can manage biomechanical forces incurred by the therapeutic agent, thereby promoting efficacy and healing. The optimized parameters can guide the practitioner in the procedure.
摘要翻译： 医生可以指定涉及递送治疗剂的过程的某些参数，同时留下其他参数。 治疗剂可以对与递送相关的生物力学力（或其他影响）敏感。 该过程可以涉及再生医学，例如使用导管将祖细胞或干细胞递送到患病心脏，由此在导管中的肆无忌惮的运输可能损害功效。 开放参数可以影响药剂的疗效，从而影响治疗效果。 基于计算机的系统可以应用诸如数据库之类的存储信息来缩小开放参数的可能值。 从缩小的可能性，优化程序可以确定开放参数的合适或优化的值。 确定的值可以管理治疗剂引起的生物力学力，从而促进功效和愈合。 优化的参数可以指导实践者在程序中。
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公开(公告)号：USD665078S1
公开(公告)日：2012-08-07
申请号：US29380432
申请日：2010-12-04
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公开(公告)号：US20120078281A1
公开(公告)日：2012-03-29
申请号：US13314011
申请日：2011-12-07
申请人： Mark A. Cox , Douglas C. Williamson , Jack C. Griffis, III , Gary A. Richardson , Andrew J. Scherer , Timothy J. Payne
发明人： Mark A. Cox , Douglas C. Williamson , Jack C. Griffis, III , Gary A. Richardson , Andrew J. Scherer , Timothy J. Payne
IPC分类号： A61B17/32
CPC分类号： A61F9/0133
摘要： A surgical tool includes a surgical blade configured to be moved to form an incision. The surgical tool also includes a wire configured to cause movement of the surgical blade. The surgical tool further includes an actuator configured to shorten a length of the wire to cause the movement of the surgical blade. The surgical tool could be configured to move the surgical blade in a first direction and then in a second direction in response to a single shortening of the wire. Also, the wire could represent a first wire, the surgical tool could include a second wire, and the surgical tool could be configured to move the surgical blade in a first direction in response to shortening the first wire and to move the surgical blade in a second direction in response to shortening the second wire.
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公开(公告)号：US20110196432A1
公开(公告)日：2011-08-11
申请号：US13016872
申请日：2011-01-28
申请人： Jack C. Griffis, III
发明人： Jack C. Griffis, III
CPC分类号： A61F2/0811 , A61F2/0805 , A61F2002/0841 , A61F2002/0858 , A61F2002/0882
摘要： Methods and devices may be used to compress and fix soft tissue to bone. Exemplary embodiments described including methods of fixing tendon to bone in an anterior cruciate ligament replacement surgery. Through compressing tendon in situ within bone, tendons may be fixed to bone while limiting axial movement of tendons and adverse effects on tendon tension.
摘要翻译： 方法和装置可以用于将软组织压缩并固定到骨骼上。 描述的示例性实施例包括在前十字韧带置换手术中将骨固定到骨的方法。 通过骨内原位压缩肌腱，可以将肌腱固定在骨上，同时限制肌腱的轴向运动和对肌腱张力的不利影响。
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