公开(公告)号：US08540082B2

公开(公告)日：2013-09-24

申请号：US13120984

申请日：2009-09-25

Applicant: James Kelland ,  Henry Petithory ,  Kevin Sullivan

Inventor： James Kelland ,  Henry Petithory ,  Kevin Sullivan

IPC: B04B5/02 ,  B04B7/00

CPC classification number: B01L3/50215 ,  A61B10/0038 ,  B01L2200/025 ,  B01L2300/0672 ,  B01L2300/0681 ,  B01L2300/0854 ,  B01L2400/0478 ,  B01L2400/0683

Abstract: A centrifugal assembly is provided that can be used in common laboratory fixed angle or swinging bucket centrifuges for the separation of material, such as parasitic ova, based on particle density. The centrifugal assembly allows the fluid level to be gently adjusted to form a meniscus without disruption of the buoyant matter, such as ova. The centrifugal assembly also enables a user to easily and hygienically collect and transfer a measured amount of a sample, such as fecal material, and to break apart and mix the sample with a floatation fluid contained in a centrifuge tube.

Abstract translation: 提供了一种离心组件，可用于普通的实验室固定角度或摆动式离心机中，用于基于颗粒密度分离材料，如寄生卵。 离心组件允许轻轻地调整液面以形成弯月面而不破坏浮力物质，例如ova。 离心组件还使得使用者能够容易且卫生地收集和转移测量量的诸如粪便材料的样品，并且将样品与包含在离心管中的浮选流体分开并混合。

公开(公告)号：US20080051692A1

公开(公告)日：2008-02-28

申请号：US11565335

申请日：2006-11-30

Applicant: John Petersen ,  Dennis Goldberg ,  James Kelland ,  Robert Ehteredge ,  Michael Barsness ,  Kuowei Chang

Inventor： John Petersen ,  Dennis Goldberg ,  James Kelland ,  Robert Ehteredge ,  Michael Barsness ,  Kuowei Chang

IPC: A61N1/30

CPC classification number: A61N1/303

Abstract: An applicator for a device for electrokinetic delivery of medicament to a treatment site includes an applicator head having an active electrode, a matrix, and a medicament or a medicament and an electrically conductive carrier, carried by the matrix in electrical contact with the electrode. The cartridge includes a plurality of raised projections allowing the matrix and head to be ultrasonically welded one to the other. The electrode opens through a face of the head remote from the matrix for connection with an electrical connector carried by the device. A lid overlies the matrix and is releasably attached to a margin of the head. The lid includes layers of different materials with one of the layers formed of a metallic material having a discontinued interface with the lid and a tab carried by the lid.

Abstract translation: 用于将药物电动递送到治疗部位的装置的施加器包括具有活性电极，基质以及由电极与电极电接触的基质携带的药物或药物和导电载体的施用器头。 盒包括多个凸起突起，允许矩阵和头被彼此超声波焊接。 电极通过远离矩阵的头部的面打开，以与由该装置承载的电连接器连接。 盖子覆盖在基体上并且可释放地附接到头部的边缘。 盖子包括不同材料的层，其中一个层由金属材料形成，该金属材料具有与盖子不连续的界面和由盖子承载的翼片。

公开(公告)号：US20090258411A1

公开(公告)日：2009-10-15

申请号：US12400364

申请日：2009-03-09

Applicant: Henry Petithory ,  James Kelland ,  Kevin Sullivan ,  Linda Martin

Inventor： Henry Petithory ,  James Kelland ,  Kevin Sullivan ,  Linda Martin

IPC: C12N1/02 ,  C12M1/00

CPC classification number: B04B5/04 ,  A61B10/0038 ,  B01L3/0272 ,  B01L3/5021 ,  B01L3/5029 ,  B01L2300/0681 ,  B04B5/0414 ,  B04B7/02 ,  B04B11/04 ,  B04B11/06 ,  B04B2005/0464 ,  B04B2005/0478

Abstract: A centrifugal device and method are provided for the separation of buoyant material such as parasitic ova from fecal matter. A rotor assembly, rotatable about its central axis in a centrifuge, includes a housing with a centrally located top opening leading to a centrally located mixing chamber. An annular sediment chamber is provided, also coaxial about the central axis, connected by a passage with the mixing chamber. A coring assembly is used to retrieve and insert a fecal sample into the mixing chamber for mixing with a flotation fluid. During centrifugation, heavier fecal components pass radially outwardly to the sediment chamber while the ova collect on the inward surface of the flotation fluid. After centrifugation, more flotation fluid is added, if needed, until a meniscus forms at the top opening. A coverslip is placed over the top opening and the ova float to the surface of the fluid and adhere to the coverslip. The coverslip is removed and the ova detected using standard microscopy procedures. In another aspect, a centrifugal device is provided in which the ova are delivered through centrifugation to a pipette tip for dispensing onto a microscope slide or coverslip.

Abstract translation: 提供了一种离心装置和方法，用于将浮力物质（例如寄生虫卵）与粪便分离。 在离心机中围绕其中心轴线旋转的转子组件包括具有中心定位的顶部开口的壳体，其通向位于中心的混合室。 提供环形沉积室，其也围绕中心轴线共轴，通过与混合室的通道连接。 取芯组件用于将粪便样品回收并插入到混合室中以与浮选流体混合。 在离心过程中，较重的粪便部件径向向外通向沉淀室，而卵子则聚集在浮选流体的内表面上。 离心后，如果需要，加入更多的浮选液，直到在顶部开口处形成弯液面。 将盖玻片放置在顶部开口上方，并且ova浮动到流体表面并粘附到盖玻片上。 取出盖玻片，使用标准显微镜检查检测到ova。 在另一方面，提供一种离心装置，其中通过离心将卵子输送到移液管尖端以分配到显微镜载玻片或盖玻片上。

公开(公告)号：US06480567B2

公开(公告)日：2002-11-12

申请号：US09780823

申请日：2001-02-09

Applicant: Francis M. Feda ,  James Kelland

Inventor： Francis M. Feda ,  James Kelland

IPC: A61B501

CPC classification number: A61N5/1001 ,  A61M2205/051

Abstract: The invention is directed toward an X-ray treatment kit to be used in an X-ray treatment apparatus. The X-ray treatment kit includes at least one of an improved biocompatible sheath or an improved probe, wherein an airflow path is maintained between the sheath and probe to allow air present within a void region of the sheath to escape as the probe is inserted therein. In various embodiments, the sheath includes a securing assembly which removably secures the sheath to the probe and provides an airflow path, e.g. an internally disposed annular ring with air shunts. Such a sheath may be used with a typical smooth probe to form an X-ray treatment kit. In other embodiments, an improved probe includes an air channel formed substantially along its length. In such a case, the improved probe may be used with a typical sheath, i.e., a sheath having a solid annular ring at its open end, to form an X-ray treatment kit.

Abstract translation: 本发明涉及用于X射线治疗装置的X射线治疗套件。 X射线治疗套件包括改进的生物相容性护套或改进的探针中的至少一种，其中在护套和探针之间保持气流路径，以允许存在于鞘的空隙区域内的空气随着探针插入其中而逸出 。 在各种实施例中，护套包括固定组件，该固定组件将护套可移除地固定到探针上并提供气流路径， 内部设置有空气分流器的环形环。 这种护套可以与典型的平滑探针一起使用以形成X射线治疗套件。 在其他实施例中，改进的探针包括基本沿其长度形成的空气通道。 在这种情况下，改进的探针可以与典型的护套一起使用，即在其开口端具有实心环形环的护套，以形成X射线治疗套件。

公开(公告)号：US20110177931A1

公开(公告)日：2011-07-21

申请号：US13120984

申请日：2009-09-25

Applicant: James Kelland ,  Henry Petithory ,  Kevin Sullivan

Inventor： James Kelland ,  Henry Petithory ,  Kevin Sullivan

IPC: B04B7/18

CPC classification number: B01L3/50215 ,  A61B10/0038 ,  B01L2200/025 ,  B01L2300/0672 ,  B01L2300/0681 ,  B01L2300/0854 ,  B01L2400/0478 ,  B01L2400/0683

Abstract: A centrifugal assembly is provided that can be used in common laboratory fixed angle or swinging bucket centrifuges for the separation of material, such as parasitic ova, based on particle density. The centrifugal assembly allows the fluid level to be gently adjusted to form a meniscus without disruption of the buoyant matter, such as ova. The centrifugal assembly also enables a user to easily and hygienically collect and transfer a measured amount of a sample, such as fecal material, and to break apart and mix the sample with a floatation fluid contained in a centrifuge tube.

Abstract translation: 提供了一种离心组件，可用于普通的实验室固定角度或摆动式离心机中，用于基于颗粒密度分离材料，如寄生卵。 离心组件允许轻轻地调整液面以形成弯月面而不破坏浮力物质，例如ova。 离心组件还使得使用者能够容易且卫生地收集和转移测量量的诸如粪便材料的样品，并且将样品与包含在离心管中的浮选流体分开并混合。

公开(公告)号：US20130048089A1

公开(公告)日：2013-02-28

申请号：US13695081

申请日：2011-04-29

Applicant: Nils B. Adey ,  Rob Parry ,  James Kelland ,  Kevin Sullivan

Inventor： Nils B. Adey ,  Rob Parry ,  James Kelland ,  Kevin Sullivan

IPC: G01N1/28 ,  F17D1/00 ,  C40B40/00

Abstract: Systems, devices, and methods for automating laboratory protocols utilizing cooperative efforts between differing components including fluidics, agitation and thermal control for processing a wide variety of disparate laboratory protocols are provided. In one aspect, a sample processing module is provided, including a housing configured to accommodate a pre-identified sample process, a temperature input capable of interfacing with a temperature controller, a fluid input capable of interfacing with an input fluid controller, a fluid output capable of interfacing with an output fluid controller, and a standardized agitation connector capable of interfacing with an agitator. A control system interfaces with the temperature input, fluid input, fluid output, and agitation connector to enable the system to perform laboratory protocols that require complex, sequential fluidic steps in association with the temperature and agitation control.

Abstract translation: 提供了使用不同组件之间的协作努力自动化实验室协议的系统，设备和方法，包括用于处理各种不同实验室协议的流体学，搅拌和热控制。 在一个方面，提供了一种样品处理模块，其包括被配置为容纳预先识别的样品过程的壳体，能够与温度控制器接口的温度输入，能够与输入流体控制器接口的流体输入，流体输出 能够与输出流体控制器接口，以及能够与搅拌器接口的标准化搅拌连接器。 控制系统与温度输入，流体输入，流体输出和搅拌连接器接口，使系统能够执行实验室协议，这些实验室协议需要与温度和搅拌控制相关联的复杂的，顺序的流程步骤。

公开(公告)号：US20070233048A1

公开(公告)日：2007-10-04

申请号：US11565360

申请日：2006-11-30

Applicant: John Petersen ,  Dennis Goldberg ,  James Kelland ,  Paul Rand ,  Anthony Jones ,  Robert Etheredge

Inventor： John Petersen ,  Dennis Goldberg ,  James Kelland ,  Paul Rand ,  Anthony Jones ,  Robert Etheredge

IPC: A61N1/30 ,  A61M5/00 ,  A61K9/22

CPC classification number: A61N1/30 ,  A61K9/0009

Abstract: A device for electrokinetic delivery of medicament to a treatment site includes a cartridge having an active electrode and a membrane overlying the active electrode and a medicament or a medicament and an electrically conductive carrier therefor, carried by the membrane in electrical contact with the electrode. The electrode opens through a surface of the cartridge remote from the membrane for connection with an electrical connector carried by the device. An locking element releasably couples the cartridge to the housing.

Abstract translation: 用于将药物电动递送到治疗部位的装置包括具有活性电极和覆盖有源电极的膜的药筒以及与电极电接触的膜携带的药物或药物及其导电载体。 电极通过远离膜的盒的表面打开，以与由装置承载的电连接器连接。 锁定元件可释放地将盒连接到壳体。

公开(公告)号：US06245047B1

公开(公告)日：2001-06-12

申请号：US09208964

申请日：1998-12-10

Applicant: Francis M. Feda ,  James Kelland

Inventor： Francis M. Feda ,  James Kelland

IPC: A61M532

CPC classification number: A61N5/1001 ,  A61M2205/051

Abstract: The invention is directed toward an X-ray treatment kit to be used in an X-ray treatment apparatus. The X-ray treatment kit includes at least one of an improved biocompatible sheath or an improved probe, wherein an airflow path is maintained between the sheath and probe to allow air present within a void region of the sheath to escape as the probe is inserted therein. In various embodiments, the sheath includes a securing assembly which removably secures the sheath to the probe and provides an airflow path, e.g. an internally disposed annular ring with air shunts. Such a sheath may be used with a typical smooth probe to form an X-ray treatment kit. In other embodiments, an improved probe includes an air channel formed substantially along its length. In such a case, the improved probe may be used with a typical sheath, i.e., a sheath having a solid annular ring at its open end, to form an X-ray treatment kit.

Abstract translation: 本发明涉及用于X射线治疗装置的X射线治疗套件。 X射线治疗套件包括改进的生物相容性护套或改进的探针中的至少一种，其中在护套和探针之间保持气流路径，以允许存在于鞘的空隙区域内的空气随着探针插入其中而逸出 。 在各种实施例中，护套包括固定组件，该固定组件将护套可移除地固定到探针上并提供气流路径， 内部设置有空气分流器的环形环。 这种护套可以与典型的平滑探针一起使用以形成X射线治疗套件。 在其他实施例中，改进的探针包括基本沿其长度形成的空气通道。 在这种情况下，改进的探针可以与典型的护套一起使用，即在其开口端具有实心环形环的护套，以形成X射线治疗套件。