公开(公告)号：US20050026811A1

公开(公告)日：2005-02-03

申请号：US10850238

申请日：2004-05-20

申请人： Adnan Mjalli ,  Robert Andrews ,  Jane Shen ,  Robert Rothlein

发明人： Adnan Mjalli ,  Robert Andrews ,  Jane Shen ,  Robert Rothlein

IPC分类号： A61K31/4164 ,  A61K31/4184 ,  A61K31/425 ,  A61P25/28 ,  A61K38/00

CPC分类号： A61K31/4164 ,  A61K31/4184 ,  A61K31/425

摘要： Disclosed are RAGE antagonist compounds that have the ability to reverse pre-existing amyloidosis. Treatment with the RAGE antagonist compounds described herein may be used to reduce plaque size and improve cognition for subjects in the later stages of Alzheimer's disease. Additionally, the RAGE antagonists described herein may be used to reduce the onset of plaque formation and thereby prevent loss of cognition and other symptoms associated with Alzheimer's Disease and other diseases of amyloid deposition.

摘要翻译： 公开了具有逆转预先存在的淀粉样变性的能力的RAGE拮抗剂化合物。 本文所述的RAGE拮抗剂化合物的治疗可用于减少斑块大小并改善阿尔茨海默病后期受试者的认知。 此外，本文所述的RAGE拮抗剂可用于减少斑块形成的发作，从而防止与阿尔茨海默病和其他淀粉样蛋白沉积疾病相关的认知和其它症状的丧失。

公开(公告)号：US20070197970A1

公开(公告)日：2007-08-23

申请号：US11466401

申请日：2006-08-22

申请人： Jane Shen-Gunther

发明人： Jane Shen-Gunther

IPC分类号： A61M5/178

CPC分类号： A61M25/0662 ,  A61B17/3415

摘要： A surgical procedure for managing postoperative pain is disclosed. More particularly, the technique involves use of intrafascial catheter introducer to thread a soaker catheter or the like through fascial sheaths of the human body (e.g., abdominal and chest walls) to relieve postoperative pain. The use of the soaker catheter in apposition to the intercostal nerves enhances the efficacy of the soaker catheter that is normally laid in the subcutaneous space. Case study results evidence the enhanced efficacy of the surgical procedure.

摘要翻译： 公开了一种用于治疗术后疼痛的外科手术。 更具体地，该技术涉及使用筋膜内导管导引器来通过人体的筋膜（例如，腹壁和胸壁）螺纹穿过导管等以减轻术后疼痛。 使用较高的导管与肋间神经相适应可增强通常铺设在皮下空间中的较高导管的功效。 案例研究结果证明了外科手术的功效增强。

公开(公告)号：US20080051746A1

公开(公告)日：2008-02-28

申请号：US11466746

申请日：2006-08-23

申请人： Jane Shen-Gunther

发明人： Jane Shen-Gunther

IPC分类号： A61F13/15

CPC分类号： A61F13/44 ,  A61M16/047 ,  A61M2205/32 ,  A61M2205/6054

摘要： A surgical sponge with an integrated RFID transponder is disclosed. A laundry RFID transponder integrated between layers of the sponge provides means for surgical personnel to verify with a RFID reader that all such sponges have been removed from a patient's body prior to an incision being closed or from a body cavity without an incision. The RFID reader may also be used post closure to re-verify that no such sponges have been inadvertently closed within the patient. A system may include a storage means and associated display device to allow for easy and convenient verification that all sponges made available for a particular surgery have all been accounted for prior to the surgical incision being closed.

摘要翻译： 公开了具有集成RFID应答器的外科海绵。 集成在海绵层之间的衣物RFID应答器为手术人员提供了使用RFID读取器验证所有这些海绵在切口闭合之前已经从患者身体移除或者没有切口的体腔的手段。 RFID读取器也可以用于封闭后重新验证在患者体内没有无意中关闭这样的海绵。 系统可以包括存储装置和相关联的显示装置，以允许容易和方便的验证，使得可用于特定手术的所有海绵在手术切口被关闭之前已被考虑。