METHODS FOR PREVENTING OR REDUCING RISK OF MORTALITY
    4.
    发明申请
    METHODS FOR PREVENTING OR REDUCING RISK OF MORTALITY 审中-公开
    防止或降低死亡风险的方法

    公开(公告)号:US20100256153A1

    公开(公告)日:2010-10-07

    申请号:US12748140

    申请日:2010-03-26

    CPC分类号: A61K31/40 A61K31/4985

    摘要: The present invention relates to methods for preventing or reducing the risk of mortality by any means including, but not limited to, cardiovascular events in mammals, particularly humans, comprising administering a dipeptidyl peptidase 4 (DPP-IV) inhibitor to the mammal or human. In addition, the present invention relates to methods for preventing or reducing the risk of non-fatal myocardial infarction and/or non-fatal stroke in mammals, particularly humans, comprising administering a DPP-IV inhibitor to the mammal or human.

    摘要翻译: 本发明涉及通过任何方式预防或降低死亡风险的方法,包括但不限于哺乳动物,特别是人类的心血管事件,包括向哺乳动物或人施用二肽基肽酶4(DPP-IV)抑制剂。 此外,本发明涉及用于预防或降低哺乳动物,特别是人类的非致命性心肌梗死和/或非致命性中风的风险的方法,包括向哺乳动物或人施用DPP-IV抑制剂。

    Protection of cardiac myocardium
    5.
    发明授权
    Protection of cardiac myocardium 有权
    保护心脏心肌

    公开(公告)号:US07504379B2

    公开(公告)日:2009-03-17

    申请号:US11129076

    申请日:2005-05-13

    IPC分类号: A61K38/18 A61K38/19

    摘要: The invention provides compositions and methods for protecting vascular tissues from injury that occurs, for example, during occlusion of one or more arteries. In some embodiments, the injury is myocardial infarction. The compositions of the invention include combinations of platelet derived growth factor, vascular endothelial growth factor, and angiopoietin-2.

    摘要翻译: 本发明提供了用于保护血管组织免受损伤的组合物和方法,例如在一个或多个动脉闭塞期间发生。 在一些实施方案中,损伤是心肌梗死。 本发明的组合物包括血小板衍生生长因子,血管内皮生长因子和血管生成素-2的组合。