公开(公告)号：US09381346B2

公开(公告)日：2016-07-05

申请号：US12319158

申请日：2009-01-02

申请人： Harry Lee ,  Allan Foreman ,  Wolfgang Daum ,  Richard Cohen ,  Jean Gotman ,  Andrew James Cole

发明人： Harry Lee ,  Allan Foreman ,  Wolfgang Daum ,  Richard Cohen ,  Jean Gotman ,  Andrew James Cole

IPC分类号： A61N1/05 ,  A61N1/36

CPC分类号： A61N1/0529 ,  A61N1/0531 ,  A61N1/36017 ,  A61N1/36025 ,  A61N1/36082

摘要： The present invention features a medical device and methods for the prevention and/or treatment of neurological disorders via electrical stimulation. These device are minimally or non-invasive and are capable of detection of a neurological disorder and its subsequent prevention or treatment. Specifically, seizure control is among the targeted therapeutic areas. Components of the device include control electronics and electrodes; the latter are targeting electrodes located entirely outside the skull and can be constructed from ring type structures or virtually connected disc type arrays. Other sub-systems included in the medical device are a control system, a battery unit, and wires connecting these and other sub-systems.

摘要翻译： 本发明的特征在于用于通过电刺激预防和/或治疗神经障碍的医疗装置和方法。 这些装置是最低限度的或非侵入性的，并且能够检测到神经障碍及其随后的预防或治疗。 具体来说，癫痫发作控制是目标治疗领域之一。 器件的组件包括控制电子器件和电极; 后者是靶向完全在颅骨外部的电极，并且可以由环形结构或虚拟连接的盘型阵列构成。 包括在医疗装置中的其他子系统是控制系统，电池单元和连接这些和其它子系统的电线。

公开(公告)号：US20110137381A1

公开(公告)日：2011-06-09

申请号：US12319158

申请日：2009-01-02

申请人： Harry Lee ,  Allan Foreman ,  Wolfgang Daum ,  Richard Cohen ,  Jean Gotman ,  Andrew James Cole

发明人： Harry Lee ,  Allan Foreman ,  Wolfgang Daum ,  Richard Cohen ,  Jean Gotman ,  Andrew James Cole

IPC分类号： A61N1/37

CPC分类号： A61N1/0529 ,  A61N1/0531 ,  A61N1/36017 ,  A61N1/36025 ,  A61N1/36082

摘要： Disclosed are medical devices for the prevention and/or treatment of neurological disorders via electrical stimulation, and methods related thereto. The devices may also be utilized to detect disorders before the prevention or treatment of a neurological disorder. These devices are minimally or non-invasive. The present medical devices comprise various components, which include electrodes and control electronics. The electrodes are targeting electrodes constructed from ring type structures or virtually connected disc type arrays. The electrodes are located entirely outside the skull. The present medical devices also comprise one or more subsystems, a control system, a battery unit, and wires connecting the one or more subsystems. These devices may also be used for acute seizure control.

摘要翻译： 公开了用于通过电刺激预防和/或治疗神经障碍的医疗装置，以及与之相关的方法。 该装置还可用于在预防或治疗神经障碍之前检测病症。 这些装置是最小的或非侵入性的。 本医疗装置包括各种部件，包括电极和控制电子装置。 电极是由环形结构或虚拟连接的盘型阵列构成的靶向电极。 电极完全位于头骨外面。 本医疗设备还包括一个或多个子系统，控制系统，电池单元以及连接所述一个或多个子系统的电线。 这些装置也可用于急性发作控制。

公开(公告)号：US06591132B2

公开(公告)日：2003-07-08

申请号：US09996587

申请日：2001-11-30

申请人： Jean Gotman ,  YunHua Wang ,  Rajeev Agarwal ,  Danny Flanagan

发明人： Jean Gotman ,  YunHua Wang ,  Rajeev Agarwal ,  Danny Flanagan

IPC分类号： A61B504

CPC分类号： A61B5/04012 ,  A61B5/0476 ,  A61B5/4094 ,  Y10S128/92 ,  Y10S128/923

摘要： A machine-readable storage medium containing a program element for execution by a computing device for performing spike and artifact detection in EG data. The program element comprises a spike detection module for processing EG data to detect spikes. Each spike is a candidate having a likelihood of being related to a physiological event of interest. The program element further comprises an artifact detection module. The artifact detection module is operative to compute respective models of events manifested by the respective spikes detected by the spike detection module, to use the computed models to determine which spikes among the spikes detected by the spike detection module have a high likelihood of being artifacts, to filter the spikes detected by the spike detection module on the basis of the computed models to produce filtered data and to output the filtered data.

摘要翻译： 一种机器可读存储介质，其包含用于在EG数据中执行尖峰和伪像检测的用于由计算设备执行的程序元素。 程序元件包括用于处理EG数据以检测尖峰的尖峰检测模块。 每个尖峰是具有与感兴趣的生理事件相关的可能性的候选者。 程序元件还包括伪影检测模块。 伪像检测模块可操作以计算由尖峰检测模块检测到的相应尖峰所表现的事件的相应模型，以使用所计算的模型来确定由尖峰检测模块检测到的尖峰中的尖峰具有很高的伪像可能性， 基于所计算的模型来过滤由尖峰检测模块检测到的峰值，以产生滤波数据并输出滤波数据。