-
公开(公告)号：US20050070571A1
公开(公告)日：2005-03-31
申请号：US10993637
申请日：2004-11-19
申请人： Patrick Mailliet , Abdekazize Laoui , Jean-Francois Riou , Gilles Doerflinger , Jean-Louis Mergny , Francois Hamy , Thomas Caulfield
发明人： Patrick Mailliet , Abdekazize Laoui , Jean-Francois Riou , Gilles Doerflinger , Jean-Louis Mergny , Francois Hamy , Thomas Caulfield
IPC分类号： A61K31/53 , C07D401/12 , C07D401/14 , C07D405/14 , C07D453/02 , A61K31/4709 , C07D41/14
CPC分类号： C07D401/14 , A61K31/53 , C07D401/12 , C07D405/14 , C07D453/02
摘要： The present invention relates to cancer therapy and to novel anticancer agents having a mechanism of action which is quite specific. It also relates to novel chemical compounds as well as their therapeutic application in humans.
摘要翻译： 本发明涉及癌症治疗和具有非常特异性的作用机制的新型抗癌剂。 它还涉及新型化合物以及它们在人体中的治疗应用。
-
公开(公告)号：US07179816B2
公开(公告)日：2007-02-20
申请号：US10954808
申请日：2004-09-30
申请人： Patrick Mailliet , Jean-Francois Riou , Marcel Alasia , Thomas Caulfield , Gilles Doerflinger , Jean-Louis Mergny , Abdelazize Laoui , Odile Petitgenet , Emmanuelle Renou
发明人： Patrick Mailliet , Jean-Francois Riou , Marcel Alasia , Thomas Caulfield , Gilles Doerflinger , Jean-Louis Mergny , Abdelazize Laoui , Odile Petitgenet , Emmanuelle Renou
IPC分类号： C07D239/50 , C07D213/02 , C07D215/38 , A61K31/505 , A61K31/506 , A61P35/00
CPC分类号： C07D401/12 , A61K31/53 , C07D401/14 , C07D453/02
摘要： The present invention relates to cancer therapy and to novel anticancer agents having a mechanism of action which inhibits telomerase. It also relates to novel chemical compounds as well as their therapeutic application in humans.
摘要翻译： 本发明涉及癌症治疗和具有抑制端粒酶的作用机制的新型抗癌剂。 它还涉及新型化合物以及它们在人体中的治疗应用。
-
3.发明授权公开(公告)号：US06706514B1
公开(公告)日：2004-03-16
申请号：US09856930
申请日：2001-06-25
IPC分类号： C12N990
摘要： The invention concerns novel polypeptides capable of interacting with the human topoisomerase III&agr; and the nucleic acid sequences coding for said polypeptides. The invention also concerns a method for identifying compounds capable of interacting with said polypeptides and a method for identifying molecules capable of modulating the interaction of the topoisomerase III&agr; with said polypeptides.
摘要翻译： 本发明涉及能够与人拓扑异构酶IIIa相互作用的新型多肽和编码所述多肽的核酸序列。 本发明还涉及鉴定能够与所述多肽相互作用的化合物的方法，以及鉴定能够调节拓扑异构酶IIIal与所述多肽的相互作用的分子的方法。
-
公开(公告)号：US07482352B2
公开(公告)日：2009-01-27
申请号：US10993637
申请日：2004-11-19
申请人： Patrick Mailliet , Abdelazize Laoui , Jean-Francois Riou , Gilles Doerflinger , Jean-Louis Mergny , Francois Hamy , Thomas Caulfield
发明人： Patrick Mailliet , Abdelazize Laoui , Jean-Francois Riou , Gilles Doerflinger , Jean-Louis Mergny , Francois Hamy , Thomas Caulfield
IPC分类号： C07D401/10 , C07D401/14 , C07D403/10 , C07D403/14 , A61K31/4427 , A61K31/4709 , A61K31/4725 , A61K31/517 , A61P35/00 , A61P35/02
CPC分类号： C07D401/14 , A61K31/53 , C07D401/12 , C07D405/14 , C07D453/02
摘要： The present invention relates to cancer therapy and to novel anticancer agents having a mechanism of action which is quite specific. It also relates to novel chemical compounds as well as their therapeutic application in humans.
摘要翻译： 本发明涉及癌症治疗和具有非常特异性的作用机制的新型抗癌剂。 它还涉及新型化合物以及它们在人体中的治疗应用。
-
5.发明申请Chemical derivatives as antitelomerase agents which bind specifically to the G-quadruplex DNA structures and their application as a specific anticancer agent 审中-公开化学衍生物作为特异性结合G-四链体DNA结构的抗端粒酶试剂及其作为特异性抗癌剂的应用公开(公告)号：US20070232572A1
公开(公告)日：2007-10-04
申请号：US10773806
申请日：2004-02-06
申请人： Augustin Hittinger , Thomas Caulfield , Patrick Mailliet , Herve Bouchard , Eliane Mandine , Jean-Louis Mergny , Lionel Guittat , Jean-Francois Riou , Dennis Gomez , Chafke Belmokhtar
发明人： Augustin Hittinger , Thomas Caulfield , Patrick Mailliet , Herve Bouchard , Eliane Mandine , Jean-Louis Mergny , Lionel Guittat , Jean-Francois Riou , Dennis Gomez , Chafke Belmokhtar
IPC分类号： A61K31/47 , A61K31/497 , A61K31/56 , A61K31/66 , C07D215/00
CPC分类号： C07D401/14 , C07D215/38
摘要： The present invention relates to cancer therapy and to novel anticancer agents having a mechanism of action which is quite specific. It also relates to novel chemical compounds and their therapeutic application in humans.
摘要翻译： 本发明涉及癌症治疗和具有非常特异性的作用机制的新型抗癌剂。 它还涉及新型化合物及其在人体中的治疗应用。
-
公开(公告)号：US20050070575A1
公开(公告)日：2005-03-31
申请号：US10954808
申请日：2004-09-30
申请人： Patrick Mailliet , Jean-Francois Riou , Marcel Alasia , Thomas Caulfield , Gilles Doerflinger , Jean-Louis Mergny , Abdelazize Laoui , Odile Petitgenet , Emmanuelle Renou
发明人： Patrick Mailliet , Jean-Francois Riou , Marcel Alasia , Thomas Caulfield , Gilles Doerflinger , Jean-Louis Mergny , Abdelazize Laoui , Odile Petitgenet , Emmanuelle Renou
IPC分类号： A61K31/53 , A61P35/00 , C07D401/12 , C07D401/14 , C07D453/02 , A61K31/4709 , C07D41/14
CPC分类号： C07D401/12 , A61K31/53 , C07D401/14 , C07D453/02
摘要： The present invention relates to cancer therapy and to novel anticancer agents having a mechanism of action which inhibits telomerase. It also relates to novel chemical compounds as well as their therapeutic application in humans.
-
公开(公告)号：US20090226411A1
公开(公告)日：2009-09-10
申请号：US12335960
申请日：2008-12-16
申请人： Patrick MAILLIET , Abdelazize LAOUI , Jean-Francois RIOU , Gilles DOERFLINGER , Jean-Louis MERGNY , Francois HAMY , Thomas CAULFIELD
发明人： Patrick MAILLIET , Abdelazize LAOUI , Jean-Francois RIOU , Gilles DOERFLINGER , Jean-Louis MERGNY , Francois HAMY , Thomas CAULFIELD
IPC分类号： A61K38/50 , C07D403/14 , A61K31/53 , A61P35/00 , A61K38/43
CPC分类号： C07D401/14 , A61K31/53 , C07D401/12 , C07D405/14 , C07D453/02
摘要： The present invention relates to cancer therapy and to novel anticancer agents having a mechanism of action which is quite specific. It also relates to novel chemical compounds as well as their therapeutic application in humans.
摘要翻译： 本发明涉及癌症治疗和具有非常特异性的作用机制的新型抗癌剂。 它还涉及新型化合物以及它们在人体中的治疗应用。
-
-
-
-
-
-
搜索结果
7 条记录 (耗时 0.017 秒)
