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公开(公告)号:US20080108069A1
公开(公告)日:2008-05-08
申请号:US11821259
申请日:2007-06-21
申请人: Rebecca Barber , Michael Barber , Peter Johnson , Sharon Gillbard , Marc Haywood , Carolyn Smith , Jennifer Arnold , Trudy Burke , Andrew Urquhart , Peter Gill
发明人: Rebecca Barber , Michael Barber , Peter Johnson , Sharon Gillbard , Marc Haywood , Carolyn Smith , Jennifer Arnold , Trudy Burke , Andrew Urquhart , Peter Gill
IPC分类号: C12Q1/68
CPC分类号: C07H21/04 , C12Q1/6827 , C12Q1/6876 , C12Q1/6881 , C12Q1/6888 , C12Q2600/156 , C12Q2600/172 , C12Q2565/125 , C12Q2545/113 , C12Q2525/151
摘要: The invention provides allelic ladder mixtures and individual alleles suitable for use in such mixtures. The allelic ladder mixtures give improved identification and distinguishing capabilities, particularly suitable in forensic investigations.
摘要翻译: 本发明提供了适用于这种混合物的等位基因梯度混合物和单个等位基因。 等位基因梯子混合物提供了更好的识别和鉴别能力,特别适用于法医调查。
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公开(公告)号:US20060029975A1
公开(公告)日:2006-02-09
申请号:US11244331
申请日:2005-10-04
申请人: Rebecca Barber , Michael Barber , Peter Johnson , Sharon Gillbard , Marc Haywood , Carolyn Smith , Jennifer Arnold , Trudy Burke , Andrew Urquhart , Peter Gill
发明人: Rebecca Barber , Michael Barber , Peter Johnson , Sharon Gillbard , Marc Haywood , Carolyn Smith , Jennifer Arnold , Trudy Burke , Andrew Urquhart , Peter Gill
CPC分类号: C07H21/04 , C12Q1/6827 , C12Q1/6876 , C12Q1/6881 , C12Q1/6888 , C12Q2600/156 , C12Q2600/172 , C12Q2565/125 , C12Q2545/113 , C12Q2525/151
摘要: The inventions provides allelic ladder mixtures and individual alleles suitable for use in such mixtures. The allelic ladder mixtures give improved identification and distinguishing capabilities, particularly suitable in forensic investigations.
摘要翻译: 本发明提供了适用于这种混合物的等位基因梯形混合物和单个等位基因。 等位基因梯子混合物提供了更好的识别和鉴别能力,特别适用于法医调查。
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公开(公告)号:US20060081644A1
公开(公告)日:2006-04-20
申请号:US11162888
申请日:2005-09-27
申请人: Jennifer ARNOLD , Kent Bruner
发明人: Jennifer ARNOLD , Kent Bruner
CPC分类号: A01K5/0291
摘要: A device for dispensing items over a programmable time so treats, toys or other items can be inserted into the dispenser, and then dispensed to pets throughout a period of time. The device can be placed out of reach of pets and then populated with items. A timer is used to actuate a dispensing unit either in intervals of gradually so that the contents are dispensed over a period of time. The device may include audible signal or odor generators to help draw attention when a device is going to be dispensed.
摘要翻译: 用于在可编程时间内分配物品的装置可以将待处理的玩具或其他物品插入分配器中,然后在一段时间内分配给宠物。 该设备可以放置在宠物接触不到的地方,然后填充物品。 使用定时器以逐渐的间隔致动分配单元,使得内容物在一段时间内被分配。 该装置可以包括可听见的信号或气味发生器,以在装置要分配时帮助引起注意。
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公开(公告)号:US20050020482A1
公开(公告)日:2005-01-27
申请号:US10480685
申请日:2002-06-14
申请人: Jennifer Phipps , Loubaba Belbaraka , Herve Jouishomme , Saba Siddiqi , Jaafar Belgoudi , Jennifer Arnold , Suzanne Lacelle
发明人: Jennifer Phipps , Loubaba Belbaraka , Herve Jouishomme , Saba Siddiqi , Jaafar Belgoudi , Jennifer Arnold , Suzanne Lacelle
IPC分类号: A61K31/00 , A61K31/137 , A61K31/352 , A61K31/522 , A61K31/70 , A61K31/7076 , A61K45/06 , A61P35/00 , C07K14/705 , C12N9/12 , C12Q1/48 , G01N33/50 , A61K38/00
CPC分类号: C12Q1/485 , A61K31/00 , A61K31/137 , A61K31/352 , A61K31/522 , A61K31/70 , A61K31/7076 , A61K45/06 , C07K14/705 , C12N9/1205 , G01N33/5008 , G01N33/5011 , G01N33/5032 , G01N33/5058 , G01N2510/00 , A61K2300/00
摘要: A method for modulating gap junctions is provided. In a first step, the transcription of connexin is enhanced and the gap junction is relocalized at the cell membrane; in a second step, gap junction function is restored by properly gating the channel and/or inducing apoptosis. The method preferably comprises a providing a cell or an animal with a first compound for increasing the activity of protein kinase A (PKA) and in the second step providing the cell or animal with a second compound for specifically inhibiting or activating one or more protein kinase C (PKC) isoforms and/or for specifically inhibiting p38 MAP kinase.
摘要翻译: 提供了一种调制间隙结的方法。 在第一步中,连接蛋白的转录增强,并且间隙连接在细胞膜上重新定位; 在第二步中,通过适当选择通道和/或诱导细胞凋亡来恢复间隙连接功能。 该方法优选包括向细胞或动物提供用于增加蛋白激酶A(PKA)活性的第一化合物,并且在第二步中向细胞或动物提供用于特异性抑制或激活一种或多种蛋白激酶的第二化合物 C(PKC)同种型和/或特异性抑制p38 MAP激酶。
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