MAMMARY GLAND- SPECIFIC HUMAN ERYTHEROPOIETIN EXPRESSION VECTOR, TRANSGENIC ANIMAL AND METHOD FOR PRODUCING HUMAN ERYTHROPOIETIN USING SAME
    2.
    发明申请
    MAMMARY GLAND- SPECIFIC HUMAN ERYTHEROPOIETIN EXPRESSION VECTOR, TRANSGENIC ANIMAL AND METHOD FOR PRODUCING HUMAN ERYTHROPOIETIN USING SAME 审中-公开
    MAMMARY GLAND特异性人ERETHEROPOIETIN表达载体,转基因动物和使用其生产人ERYTHROPOIETIN的方法

    公开(公告)号:US20100205680A1

    公开(公告)日:2010-08-12

    申请号:US12733087

    申请日:2007-08-08

    申请人: Jin Hoi Kim

    发明人: Jin Hoi Kim

    摘要: The present invention provides a mammary gland-specific human erythropoietin expression (hEPO) vector, transgenic animal and method for producing human erythropoietin using the same. The inventive hEPO-expressing transgenic animals express a mammary gland-specific EPO at an extremely higher concentration than the convention method. The hEPO produced from inventive transgenic animals shows better stability and superior physiological activity than those of the same kind of commerally available protein. Therefore, the inventive hEPO-expressing transgenic animals can be effectively used for production of EPO showing a superior physiological activity than the existing EPO.

    摘要翻译: 本发明提供了一种乳腺特异性人促红细胞生成素表达(hEPO)载体,转基因动物以及使用其的人促红细胞生成素的制备方法。 本发明的表达hEPO的转基因动物以比常规方法更高的浓度表达乳腺特异性EPO。 由本发明的转基因动物产生的hEPO显示比相同种类的市售蛋白质更好的稳定性和优异的生理活性。 因此,本发明的表达hEPO的转基因动物可有效地用于产生与现有EPO相比优异的生理活性的EPO。

    Hand-tearable adhesive tape and method for manufacturing the same
    3.
    发明授权
    Hand-tearable adhesive tape and method for manufacturing the same 有权
    手撕胶带及其制造方法

    公开(公告)号:US09034424B2

    公开(公告)日:2015-05-19

    申请号:US13178075

    申请日:2011-07-07

    IPC分类号: B05D5/10 C09J7/04 C08K5/00

    摘要: Disclosed are a hand-tearable adhesive tape which is made of a sheet woven with warps and wefts, in which the warps have a smaller titer than the wefts, and is coated with a flame retardant to provide flame retardancy and is with an adhesive agent, and a method for manufacturing the same. Advantageously, the hand-tearable adhesive tape can exhibit superior adhesive force, while providing flame retardancy and can be torn by hand.

    摘要翻译: 本发明公开了一种手工胶粘带,其由经纱和纬纱编织的片材制成,其中经纱具有比纬纱更低的滴定度,并且涂覆有阻燃剂以提供阻燃性并且具有粘合剂, 及其制造方法。 有利地,可手撕胶带可以表现出优异的粘合力,同时提供阻燃性并且可以用手撕裂。

    Porcine uroplakin ii promoter and the production method of useful proteins using said promoter
    4.
    发明申请
    Porcine uroplakin ii promoter and the production method of useful proteins using said promoter 失效
    猪尿泌素ii启动子和使用所述启动子的有用蛋白质的生产方法

    公开(公告)号:US20060236412A1

    公开(公告)日:2006-10-19

    申请号:US10532580

    申请日:2003-11-04

    申请人: Jin-Hoi Kim

    发明人: Jin-Hoi Kim

    摘要: The present invention relates to a porcine uroplakin II gene promoter, an expression vector containing the promoter, and a method for producing useful proteins using the vector. The promoter of the present invention promotes the bladder-specific expression of a target protein at high efficiency. An animal, which was transformed using the inventive promoter so as to express the target protein, secretes the target protein in its urine at high concentration, and the protein thus produced shows a superior physiological activity to that of the same kind of the existing protein. As a result, the inventive promoter, the expression vector and transgenic animal using the promoter, can be advantageously used in the production field of useful proteins that are medicinally valuable.

    摘要翻译: 本发明涉及猪尿泌素II基因启动子,含有启动子的表达载体,以及使用载体生产有用蛋白质的方法。 本发明的启动子以高效率促进靶蛋白的膀胱特异性表达。 使用本发明的启动子转化以表达靶蛋白的动物以高浓度分泌其尿液中的靶蛋白,并且所产生的蛋白质显示出与现有蛋白质相同的生理活性。 结果,本发明的启动子,表达载体和使用启动子的转基因动物可以有利地用于有用的有用的蛋白质的生产领域。

    Gene of porcine beta casein, a promoter of the same and the use thereof
    5.
    发明授权
    Gene of porcine beta casein, a promoter of the same and the use thereof 有权
    猪β酪蛋白的基因,其启动子及其用途

    公开(公告)号:US08420388B2

    公开(公告)日:2013-04-16

    申请号:US12737318

    申请日:2008-12-31

    CPC分类号: C07K14/4732

    摘要: The present invention provides a porcine beta-casein gene, a porcine beta-casein gene promoter, an expression vector comprising the same promoter, and a method for the production of a target protein using the same expression vector. The promoter of the present invention facilitates mammary gland-specific expression of the target protein and therefore can be useful for high-concentration production of beneficial proteins in milk.

    摘要翻译: 本发明提供猪β-酪蛋白基因,猪β-酪蛋白基因启动子,包含相同启动子的表达载体,以及使用相同表达载体产生靶蛋白的方法。 本发明的启动子有助于靶蛋白的乳腺特异性表达,因此可用于高浓度生产牛奶中的有益蛋白质。

    Porcine uroplakin II promoter and the production method of useful proteins using said promoter
    7.
    发明授权
    Porcine uroplakin II promoter and the production method of useful proteins using said promoter 失效
    猪尿泌素II启动子和使用所述启动子的有用蛋白质的制备方法

    公开(公告)号:US07416886B2

    公开(公告)日:2008-08-26

    申请号:US10532580

    申请日:2003-11-04

    申请人: Jin-Hoi Kim

    发明人: Jin-Hoi Kim

    摘要: The present invention relates to a porcine uroplakin II gene promoter, an expression vector containing the promoter, and a method for producing useful proteins using the vector. The promoter of the present invention promotes the bladder-specific expression of a target protein at high efficiency. An animal, which was transformed using the inventive promoter so as to express the target protein, secretes the target protein in its urine at high concentration, and the protein thus produced shows a superior physiological activity to that of the same kind of the existing protein. As a result, the inventive promoter, the expression vector and transgenic animal using the promoter, can be advantageously used in the production field of useful proteins that are medicinally valuable.

    摘要翻译: 本发明涉及猪尿泌素II基因启动子,含有启动子的表达载体,以及使用载体生产有用蛋白质的方法。 本发明的启动子以高效率促进靶蛋白的膀胱特异性表达。 使用本发明的启动子转化以表达靶蛋白的动物以高浓度分泌其尿液中的靶蛋白,并且所产生的蛋白质显示出与现有蛋白质相同的生理活性。 结果,本发明的启动子,表达载体和使用启动子的转基因动物可以有利地用于有用的有用的蛋白质的生产领域。