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1.发明申请公开(公告)号：US20090129989A1
公开(公告)日：2009-05-21
申请号：US12358711
申请日：2009-01-23
申请人： Ernest Balestracci , James A. Melchore, Jr. , Jo Anna Monteferrante , Irene Kucharewicz Ropiak , Ernst Schramm , Julius P. Zodda , Charles R. Quirico
发明人： Ernest Balestracci , James A. Melchore, Jr. , Jo Anna Monteferrante , Irene Kucharewicz Ropiak , Ernst Schramm , Julius P. Zodda , Charles R. Quirico
CPC分类号： F16L37/2445 , A61M5/1785 , A61M5/445 , A61M39/20 , G21G4/08
摘要： The invention is directed to improved containers for pharmaceuticals and any tubing and tubing connectors associated therewith, particularly containers for pharmaceuticals which are irradiated, heated or otherwise subjected to increased pressure. In a preferred embodiment, the invention is directed to an improved container for use in a radioisotope generator, such as a rubidium-82 generator.
摘要翻译： 本发明涉及用于药物的改进容器和与其相关联的任何管道和管道连接器，特别是用于被照射，加热或以其他方式施加增加压力的药物的容器。 在优选实施方案中，本发明涉及用于放射性同位素发生器例如铷-82发生器的改进容器。
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2.发明授权Containers for pharmaceuticals, particularly for use in radioisotope generators 有权用于药物的容器，特别用于放射性同位素发生器公开(公告)号：US07504646B2
公开(公告)日：2009-03-17
申请号：US10597456
申请日：2005-08-30
申请人： Ernest Balestracci , James A. Melchore, Jr. , Jo Anna Monteferrante , Irene Kucharewicz Ropiak , Ernst Schramm , Julius P. Zodda , Charles Quirico
发明人： Ernest Balestracci , James A. Melchore, Jr. , Jo Anna Monteferrante , Irene Kucharewicz Ropiak , Ernst Schramm , Julius P. Zodda , Charles Quirico
IPC分类号： G21F5/00
CPC分类号： F16L37/2445 , A61M5/1785 , A61M5/445 , A61M39/20 , G21G4/08
摘要： The invention is directed to improved containers for pharmaceuticals and any tubing and tubing connectors associated therewith, particularly containers for pharmaceuticals which are irradiated, heated or otherwise subjected to increased pressure. In a preferred embodiment, the invention is directed to an improved container for use in a radioisotope generator, such as a rubidium-82 generator.
摘要翻译： 本发明涉及用于药物的改进容器和与其相关联的任何管道和管道连接器，特别是用于被照射，加热或以其他方式施加增加压力的药物的容器。 在优选实施方案中，本发明涉及用于放射性同位素发生器例如铷-82发生器的改进容器。
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公开(公告)号：US20120128581A1
公开(公告)日：2012-05-24
申请号：US13309848
申请日：2011-12-02
申请人： Edmund C. Metcalfe , Jo Anna Monteferrante , Margaret Newborn , Irene Ropiak , Ernst Schramm , Gregory W. White , Julius P. Zodda
发明人： Edmund C. Metcalfe , Jo Anna Monteferrante , Margaret Newborn , Irene Ropiak , Ernst Schramm , Gregory W. White , Julius P. Zodda
CPC分类号： A61K38/08 , A61K9/0019 , A61K38/2207 , A61K47/02 , A61K47/10 , A61K47/18 , A61K47/183 , A61K47/186 , A61K47/20 , A61K47/26 , A61K49/0002 , A61K51/0402 , Y10S514/951
摘要： The invention features sincalide formulations that include an effective amount of sincalide, a bulking agent/tonicity adjuster, a stabilizer, a surfactant, a chelator, and a buffer. The invention also features kits and methods for preparing improved sincalide formulations as well as methods for treating, preventing, and diagnosing gall bladder-related disorders using sincalide formulations.
摘要翻译： 本发明的特征在于包含有效量的辛香碱，填充剂/张力调节剂，稳定剂，表面活性剂，螯合剂和缓冲剂的辛卡利特制剂。 本发明还提供了用于制备改进的辛沙利肽制剂的试剂盒和方法，以及使用辛酰胆碱制剂治疗，预防和诊断胆囊相关病症的方法。
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公开(公告)号：US20100047175A1
公开(公告)日：2010-02-25
申请号：US12607337
申请日：2009-10-28
申请人： Edmund C. Metcalfe , Jo Anna Monteferrante , Margaret Newborn , Irene Ropiak , Ernst Schramm , Gregory W. White , Julius P. Zodda
发明人： Edmund C. Metcalfe , Jo Anna Monteferrante , Margaret Newborn , Irene Ropiak , Ernst Schramm , Gregory W. White , Julius P. Zodda
CPC分类号： A61K38/08 , A61K9/0019 , A61K38/2207 , A61K47/02 , A61K47/10 , A61K47/18 , A61K47/183 , A61K47/186 , A61K47/20 , A61K47/26 , A61K49/0002 , A61K51/0402 , Y10S514/951
摘要： The invention features sincalide formulations that include an effective amount of sincalide, a bulking agent/tonicity adjuster, a stabilizer, a surfactant, a chelator, and a buffer. The invention also features kits and methods for preparing improved sincalide formulations as well as methods for treating, preventing, and diagnosing gall bladder-related disorders using sincalide formulations.
摘要翻译： 本发明的特征在于包含有效量的辛香碱，填充剂/张力调节剂，稳定剂，表面活性剂，螯合剂和缓冲剂的辛卡利特制剂。 本发明还提供了用于制备改进的辛沙利肽制剂的试剂盒和方法，以及使用辛酰胆碱制剂治疗，预防和诊断胆囊相关病症的方法。
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5.发明授权Containers for pharmaceuticals, particularly for use in radioisotope generators 有权用于药物的容器，特别用于放射性同位素发生器公开(公告)号：US08058632B2
公开(公告)日：2011-11-15
申请号：US12358711
申请日：2009-01-23
申请人： Ernest Balestracci , James A. Melchore, Jr. , Jo Anna Monteferrante , Irene Kucharewicz Ropiak , Ernst Schramm , Julius P. Zodda , Charles R. Quirico
发明人： Ernest Balestracci , James A. Melchore, Jr. , Jo Anna Monteferrante , Irene Kucharewicz Ropiak , Ernst Schramm , Julius P. Zodda , Charles R. Quirico
IPC分类号： G21F5/00
CPC分类号： F16L37/2445 , A61M5/1785 , A61M5/445 , A61M39/20 , G21G4/08
摘要： The invention is directed to improved containers for pharmaceuticals and any tubing and tubing connectors associated therewith, particularly containers for pharmaceuticals which are irradiated, heated or otherwise subjected to increased pressure. In a preferred embodiment, the invention is directed to an improved container for use in a radioisotope generator, such as a rubidium-82 generator.
摘要翻译： 本发明涉及用于药物的改进容器和与其相关联的任何管道和管道连接器，特别是用于被照射，加热或以其他方式施加增加压力的药物的容器。 在优选实施方案中，本发明涉及用于放射性同位素发生器例如铷-82发生器的改进容器。
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6.发明申请IMPROVED CONTAINERS FOR PHARMACEUTICALS, PARTICULARLY FOR USE IN RADIOISOTOPE GENERATORES 有权用于药物的改进容器，特别用于放射性发生器公开(公告)号：US20090016936A2
公开(公告)日：2009-01-15
申请号：US10597456
申请日：2007-01-17
申请人： Ernest Balestracci , James Melchore , Jo Anna Monteferrante , Irene Kucharewicz Ropiak , Ernst Schramm , Julius Zodda , Charles Quirico
发明人： Ernest Balestracci , James Melchore , Jo Anna Monteferrante , Irene Kucharewicz Ropiak , Ernst Schramm , Julius Zodda , Charles Quirico
CPC分类号： F16L37/2445 , A61M5/1785 , A61M5/445 , A61M39/20 , G21G4/08
摘要： The invention is directed to improved containers for pharmaceuticals and any tubing and tubing connectors associated therewith, particularly containers for pharmaceuticals which are irradiated, heated or otherwise subjected to increased pressure. In a preferred embodiment, the invention is directed to an improved container for use in a radioisotope generator, such as a rubidium-82 generator.
摘要翻译： 本发明涉及用于药物的改进容器和与其相关联的任何管道和管道连接器，特别是用于被照射，加热或以其他方式施加增加压力的药物的容器。 在优选实施方案中，本发明涉及用于放射性同位素发生器例如铷-82发生器的改进容器。
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公开(公告)号：US06803046B2
公开(公告)日：2004-10-12
申请号：US10222540
申请日：2002-08-16
申请人： Edmund C. Metcalfe , Jo Anna Monteferrante , Margaret Newborn , Irene Ropiak , Ernst Schramm , Gregory W. White , Julius P. Zodda
发明人： Edmund C. Metcalfe , Jo Anna Monteferrante , Margaret Newborn , Irene Ropiak , Ernst Schramm , Gregory W. White , Julius P. Zodda
IPC分类号： A61K900
CPC分类号： A61K38/08 , A61K9/0019 , A61K38/2207 , A61K47/02 , A61K47/10 , A61K47/18 , A61K47/183 , A61K47/186 , A61K47/20 , A61K47/26 , A61K49/0002 , A61K51/0402 , Y10S514/951
摘要： The invention features sincalide formulations that include an effective amount of sincalide, a bulking agent/tonicity adjuster, a stabilizer, a surfactant, a chelator, and a buffer. The invention also features kits and methods for preparing improved sincalide formulations, as well as methods for treating, preventing, and diagnosing gall bladder-related disorders using sincalide formulations.
摘要翻译： 本发明的特征在于包含有效量的辛香碱，填充剂/张力调节剂，稳定剂，表面活性剂，螯合剂和缓冲剂的辛卡利特制剂。 本发明还提供了用于制备改进的辛沙利肽制剂的试剂盒和方法，以及使用辛酰胆碱制剂治疗，预防和诊断胆囊相关疾病的方法。
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8.发明授权Kit for the preparation of technetium TC 99m teboroxime myocardial perfusion agent 有权用于制备锝TC 99m teboroxime心肌灌注剂的试剂盒
公开(公告)号：US6056941A
公开(公告)日：2000-05-02
申请号：US363132
申请日：1999-07-28
CPC分类号： B82Y5/00 , A61K51/0474 , A61K51/1268 , A61K51/1282
摘要： A kit containing a solution of boronic acid adducts of technetium-99 m dioxime complexes; and hydroxypropyl gamma cyclodextrin to maintain the solution free of particulate matter originating from the formulation.
摘要翻译： 含有锝-99m二肟配合物的硼酸加合物溶液的试剂盒; 和羟丙基γ-环糊精以保持溶液不含来自制剂的颗粒物质。
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