Abstract:
The invention provides a method of enhancing the action of a pharmaceutical agent selected from the group consisting of the anti-infective agents, the group comprising of the antimicrobial agents, the anthelmintic agents and the anti-ectoparasitic agents, but excluding coal tar solution and H1-antagonist antihistamines, and from the group consisting of the CPNS agents selected from the group of compounds acting on the central or peripheral nervous system, but excluding coal tar solution and H1-antagonist antihistamines and also excluding anti-inflammatory, analgesic and antipyretic agents and also provides an enhanced method for the administration of a nucleic acid substance to the cells of an animal, a plant or a micro-organism. The method is characterized in that the agent or nucleic acid substance is formulated with an administration medium which comprises a solution of nitrous oxide gas in a pharmaceutically acceptable carrier solvent for the gas and which administration medium includes at least one fatty acid or ester or other suitable derivative thereof selected from the group consisting of oleic acid, linoleic acid, alpha-linolenic acid, gamma-linolenic acid, arachidonic acid, eicosapentaenoic acid [C20:5ω3], decosahexaenoic acid [C22:6ω3], ricinoleic acid and derivatives thereof selected from the group consisting of the C1 to C6 alkyl esters thereof, the glycerol-polyethylene glycol esters thereof and the reaction product of hydrogenated natural oils composed largely of ricinoleic acid based oils, such as castor oil with ethylene oxide. The formulations of such agents or substances form part of the invention.
Abstract:
Valve drive for an internal combustion engine having a valve which is axially displaceable between an open position and a closed position and is prestressed by a locking spring in the direction of its closed position, in which a control shaft driven by an electric motor to pivot about a longitudinal axis, has a cam, provided for operating the valve a pressure element that can be pivoted about a pivot axis, and a spring element which prestresses the pressure element and exerts a torque on the control shaft via the pressure element. The mass moment of inertia of the pressure element relative to its pivot axis is greater than the mass moment of inertia of the control shaft and the cam relative to the longitudinal axis of the control shaft. The valve drive so configured provides greater electrical operating efficiency and permits valve actuation to be performed at lower electric motor rotation speeds.
Abstract:
For a rotary actor device for stroke control of a charge changing valve in the cylinder head of an internal combustion engine with rocking stepper motor for driving a control disk with a cam profile controlling a charge changing valve, wherein the rocking motor is operated accordingly, an interplay of a closing spring of the poppet valve with a biased spring arm, provision is made for the achievement of stable end positions of the control disk, such that it is positioned by means of a separate first and second rotary abutment and is held securely against rotation in the particular starting position by the opening spring acting on a shaft bearing the control disk, while in each case by means of a relatively low powering of the stepper motor or of a ricochet movement brought about by means of corresponding abutments to overcome the starting position, the further supply of power remains substantially reduced by means of a rotor of the rocker motor chosen according to the energy exchange between closing spring and arm spring in a rotor of the rocker motor chosen to correspond to its flywheel moment.
Abstract:
An electromagnetic valve actuating mechanism for an internal combustion engine has an axially displaceable control element with an armature plate, for opening or closing a valve. Two solenoids are arranged behind one another in the displacement direction and spaced with respect to one another. One solenoid is arranged on the side of the armature plate close to the valve and the other is on the side away from the valve. Two springs are arranged behind one another in the displacement direction, one of the springs being arranged on the side of the armature plate close to the valve and the other being arranged on the side away from the valve. The control element, which is held in a neutral position when the solenoids are currentless, is deflectable from its neutral position by energizing the solenoids. An adjusting element, which rests on the end of one of the two springs away from the armature plate, is adjustable to change the prestressing of the springs and the location of the neutral position of the control element. The adjusting element, which is displaceably arranged in the displacement direction, is displaceable via an actuating device during the operation of the valve actuating mechanism, for adjusting of the neutral position.
Abstract:
The invention relates to a therapeutic device to promote the healing of a wound, comprising a porous paid which is permeable for fluids to place on the wound, a bandage to cover the wound and to provide an essentially airtight seal around the wound, a drainage line connecting the pad with a suction pump so that suction can be applied to the wound to draw the fluids away from it, whereby the line is connected to the suction pump via a canister to collect fluid sucked from the wound, a connector to connect the pad to the drainage line, means to determine a prevailing wound pressure basically comprising the wound and this surrounding skin area, as well as a control unit to control the wound pressure. In order to generally improve metrology with the goal of making possible a more reliable and more secure dressing of the wound, and also to design metrology in an especially simple and error-free way, it is proposed that the pad interconnect the suction pump solely via the drainage line.
Abstract:
A geotechnical barrier includes a first barrier layer; a second barrier layer overlying the first barrier layer and spaced therefrom, the first and second barrier layers defining, at least in part, a fluid passageway having an inlet and an outlet; and fluid displacement means for displacing a fluid through said fluid passageway from the inlet to the outlet. The invention extends to method for constructing and operating a geotechnical barrier and to a geosynthetic barrier and a geocomposite geosynthetic barrier.
Abstract:
An electromagnetic valve actuating mechanism for an internal combustion engine has an axially displaceable control element with an armature plate, for opening or closing a valve. Two solenoids are arranged behind one another in the displacement direction and spaced with respect to one another. One solenoid is arranged on the side of the armature plate close to the valve and the other is on the side away from the valve. Two springs are arranged behind one another in the displacement direction, one of the springs being arranged on the side of the armature plate close to the valve and the other being arranged on the side away from the valve. The control element, which is held in a neutral position when the solenoids are currentless, is deflectable from its neutral position by energizing the solenoids. An adjusting element, which rests on the end of one of the two springs away from the armature plate, is adjustable to change the prestressing of the springs and the location of the neutral position of the control element. The adjusting element, which is displaceably arranged in the displacement direction, is displaceable via an actuating device during the operation of the valve actuating mechanism, for adjusting of the neutral position.
Abstract:
A rotary actuator device is used to control the stroke of at least two gas exchange valves in a cylinder head of an internal combustion engine. The device includes first and second actuating mechanisms, first and second rocker motors, and a force transfer element. Each actuating mechanism is provided for at least one of the gas exchange valves of the engine. The first rocker motor has a first shaft on which the first actuating mechanism is disposed, and the second rocker motor has a second shaft on which the second actuating mechanism is disposed. The first and the second rocker motors are arranged in a point-mirrored relationship. The force transfer element is disposed between each actuating mechanism and the at least one gas exchange valve.
Abstract:
The present invention pertains to a valve actuating lever having a non-cut formed oblong base body which is configured essentially symmetrical to a longitudinal symmetry plane extending essentially longitudinally therefrom, a valve contact area arranged on a first end of said base body, two tabs arranged on both sides of said longitudinal symmetry plane in said valve contact area, each respectively having a lateral surface aligned facing said longitudinal symmetry plane, whereby said tabs are formed on said base body and bent over toward said valve contact area. Said tabs are arranged spaced at a clearance distance at an end edge of said oblong base body, said clearance distance being less than the clearance of said lateral surfaces in the valve contact area. At least one of the tabs has a connecting portion extending from said longitudinal symmetry plane in which the clearance between said lateral surfaces enlarges as well as at least one parallel portion in which said lateral surfaces extend essentially parallel to said longitudinal symmetry plane.
Abstract:
Administration mediums comprising solutions of nitrous oxide in water, alcohols, ethers or oils, and optionally including essential fatty acids or C1-C6 alkyl esters thereof enhance the action of analgesic, anti-inflammatory and anti-pyretic drugs. The drugs may be combined with the medium into a pharmaceutical composition or may be taken orally by swallowing the drug with the aid of the medium.