Minimally invasive, sustained, intra-tympanic drug delivery system
    1.
    发明申请
    Minimally invasive, sustained, intra-tympanic drug delivery system 有权
    微创,持续,鼓室内药物输送系统

    公开(公告)号:US20050182385A1

    公开(公告)日:2005-08-18

    申请号:US11039556

    申请日:2005-01-20

    申请人: John Epley

    发明人: John Epley

    IPC分类号: A61M5/142 A61M5/158 A61M31/00

    摘要: A convenient and preferably wearable system and method for implementing the controlled and sustained delivery of a medical liquid through the tympanic membrane and into the middle ear including port structure that produces a minimal opening in the membrane, a wearable and fixated fluid-conduit structure coupleable to the port structure, a reservoir adapted to contain delivery fluid, and an operationally controllable pump system applied to the fluid conduit structure, and/or an iontophoretic electrode system applied within the fluid conduit structure and to the subject's body, and operable to effect the delivery of reservoir-held fluid or medically active ions through the fluid conduit and port structures to the middle ear.

    摘要翻译: 用于实现医疗液体通过鼓膜的受控和持续输送并进入中耳的方便且优选的可穿戴系统和方法,包括在膜中产生最小开口的端口结构,可穿戴和固定的流体 - 管道结构,其可耦合到 端口结构,适于容纳输送流体的储存器和应用于流体导管结构的可操作可控的泵系统,和/或应用于流体导管结构内和离子电渗疗法电极系统,并且可操作以实现递送 储存器保持的流体或医用活性离子通过流体导管和端口结构到中耳。

    Hemispheroidal-truss spatial manipulator system and apparatus
    2.
    发明授权
    Hemispheroidal-truss spatial manipulator system and apparatus 有权
    半球形桁架空间机械手系统和装置

    公开(公告)号:US07559766B2

    公开(公告)日:2009-07-14

    申请号:US11289201

    申请日:2005-11-28

    IPC分类号: G09B19/16

    摘要: Spatial manipulator apparatus for a mammalian subject includes a stabilizing base; a hemispheroidal truss frame mounted for rotation on the stabilizing base, the truss frame supporting and stabilizing an outer generally circular rim in relation to a non-concentric hub located at its rotational axis; and a second frame mounted orthogonally within the outer rim on a second rotational axis, the second frame being configured to support a mammalian subject during spatial manipulation thereof by rotation about one or more of the orthogonal rotational axes. Preferably, the truss frame and the second frame are driven for rotation about the orthogonal rotational axes to achieve a desired mammalian-subject spatial orientation within a chair-like structure pivotally adjustably mounted within the second frame. Preferably, the truss frame includes a substantially circular rim member mounting the second frame for rotation therein; three or more struts connecting from circumferential substantially evenly spaced locations along the circular rim member to a point of convergence on the truss frame through which the first axis extends; and a hub at the point of convergence mounting the three or more struts.

    摘要翻译: 用于哺乳动物受试者的空间操纵器装置包括稳定基座; 相对于位于其旋转轴线的非同心轮毂,桁架架支撑并稳定外部大致圆形的边缘,所述半球形桁架框架安装成在稳定基座上旋转, 以及第二框架,其正交地安装在第二旋转轴线的外缘内,所述第二框架构造成在通过绕所述正交旋转轴线的一个或多个的旋转进行空间操纵期间支撑哺乳动物受试者。 优选地,桁架框架和第二框架被驱动以围绕正交旋转轴线旋转,以在可枢转地调节地安装在第二框架内的椅子状结构内实现期望的哺乳动物对象空间取向。 优选地,桁架框架包括安装第二框架以在其中旋转的大致圆形的边缘构件; 三个或更多个支柱,其沿周向基本上均匀间隔的位置沿着圆形边缘构件连接到第一轴线所延伸的桁架框架上的会聚点; 并且在汇合点安装三个或更多个支柱的枢纽。

    Hemispheroidal-truss spatial manipulator system and apparatus
    3.
    发明申请
    Hemispheroidal-truss spatial manipulator system and apparatus 有权
    半球形桁架空间机械手系统和装置

    公开(公告)号:US20070167886A1

    公开(公告)日:2007-07-19

    申请号:US11289201

    申请日:2005-11-28

    IPC分类号: A61H7/00

    摘要: Spatial manipulator apparatus for a mammalian subject includes a stabilizing base; a hemispheroidal truss frame mounted for rotation on the stabilizing base, the truss frame supporting and stabilizing an outer generally circular rim in relation to a non-concentric hub located at its rotational axis; and a second frame mounted orthogonally within the outer rim on a second rotational axis, the second frame being configured to support a mammalian subject during spatial manipulation thereof by rotation about one or more of the orthogonal rotational axes. Preferably, the truss frame and the second frame are driven for rotation about the orthogonal rotational axes to achieve a desired mammalian-subject spatial orientation within a chair-like structure pivotally adjustably mounted within the second frame. Preferably, the truss frame includes a substantially circular rim member mounting the second frame for rotation therein; three or more struts connecting from circumferential substantially evenly spaced locations along the circular rim member to a point of convergence on the truss frame through which the first axis extends; and a hub at the point of convergence mounting the three or more struts.

    摘要翻译: 用于哺乳动物受试者的空间操纵器装置包括稳定基座; 相对于位于其旋转轴线的非同心轮毂,桁架架支撑并稳定外部大致圆形的边缘,所述半球形桁架框架安装成在稳定基座上旋转, 以及第二框架,其正交地安装在第二旋转轴线的外缘内,所述第二框架构造成在通过绕所述正交旋转轴线的一个或多个的旋转进行空间操纵期间支撑哺乳动物受试者。 优选地,桁架框架和第二框架被驱动以围绕正交旋转轴线旋转,以在可枢转地调节地安装在第二框架内的椅子状结构内实现期望的哺乳动物对象空间取向。 优选地,桁架框架包括安装第二框架以在其中旋转的大致圆形的边缘构件; 三个或更多个支柱,其沿周向基本上均匀间隔的位置沿着圆形边缘构件连接到第一轴线所延伸的桁架框架上的会聚点; 并且在汇合点安装三个或更多个支柱的枢纽。

    Head-stabilized medical apparatus, system and methodology
    4.
    发明申请
    Head-stabilized medical apparatus, system and methodology 审中-公开
    头部稳定的医疗器械,系统和方法

    公开(公告)号:US20100268125A9

    公开(公告)日:2010-10-21

    申请号:US10715871

    申请日:2003-11-17

    申请人: John Epley

    发明人: John Epley

    IPC分类号: A61B5/103 A61B5/117 A61B5/00

    摘要: Structure and methodology involving mountable and head-wearable frame structure which is positionally stabilized, during use, relative a human subject's head, and which carries a selection of positionally anchored data sensors, and stimuli deliverers, that are relevant to the diagnosis and treatment of vestibular disorders. Special configurations are provided for two types of stimulators, one for sound application and air-pressure modification, and the other for the introduction of fluids to the ear. Stabilization enables tight and accurate correlation of data which is quickly analyzable by a connected, properly algorithmed computer, which can also be used for feedback control in a designed “expert” system. The invention enables, among other things, practical and significant differentiation between physiological and pathological nystagmus.

    摘要翻译: 结构和方法涉及可安装和头戴式框架结构,其在使用期间位置稳定,相对于人类受试者的头部,并且其携带与前庭的诊断和治疗相关的位置锚定数据传感器和刺激提供者的选择 疾病 为两种类型的刺激器提供特殊配置,一种用于声音应用和气压修改,另一种用于将流体引入耳朵。 稳定化使得可以通过连接的,适当的算法计算机快速分析数据的紧密和准确的相关性,这也可以用于设计的“专家”系统中的反馈控制。 本发明除了别的以外能够使生理和病理性眼球震颤之间的实际和显着的分化。

    Head-stabilized medical apparatus, system and methodology
    5.
    发明申请
    Head-stabilized medical apparatus, system and methodology 有权
    头部稳定的医疗器械,系统和方法

    公开(公告)号:US20070161875A1

    公开(公告)日:2007-07-12

    申请号:US11714459

    申请日:2007-03-05

    申请人: John Epley

    发明人: John Epley

    IPC分类号: A61B5/00 A61B13/00 A61B5/103

    摘要: Structure and methodology involving mountable and head-wearable frame structure which is positionally stabilized, during use, relative a human subject's head, and which carries a selection of positionally anchored data sensors, and stimuli deliverers, that are relevant to the diagnosis and treatment of vestibular disorders. Special configurations are provided for two types of stimulators, one for sound application and air-pressure modification, and the other for the introduction of fluids to the ear. Stabilization enables tight and accurate correlation of data which is quickly analyzable by a connected, properly algorithmed computer, which can also be used for feedback control in a designed “expert” system. The invention enables, among other things, practical and significant differentiation between physiological and pathological nystagmus.

    摘要翻译: 结构和方法涉及可安装和头戴式框架结构,其在使用期间位置稳定,相对于人类受试者的头部,并且其携带与前庭的诊断和治疗相关的位置锚定数据传感器和刺激提供者的选择 疾病 为两种类型的刺激器提供特殊配置,一种用于声音应用和气压修改,另一种用于将流体引入耳朵。 稳定化使得可以通过连接的,适当的算法计算机快速分析数据的紧密和准确的相关性,这也可以用于设计的“专家”系统中的反馈控制。 本发明除了别的以外能够使生理和病理性眼球震颤之间的实际和显着的分化。