Antibiotic and fermentation process of preparing
    3.
    发明授权
    Antibiotic and fermentation process of preparing 失效
    抗生素和发酵过程的准备

    公开(公告)号:US4251511A

    公开(公告)日:1981-02-17

    申请号:US81104

    申请日:1979-10-02

    CPC分类号: C12R1/01 C12P1/06

    摘要: Novel antibiotic U-59,761 producible in a fermentation under controlled conditions using a biologically pure culture of the microorganism Saccharopolyspora hirsuta strain 367, NRRL 12045. This antibiotic is active against various microorganisms, for example, Staphylococcus aureus, Streptococcus pyogenes, Sarcina lutea, Klebsiella pneumoniae, Mycobacterium avium, and Bacteroides fragilis. Thus, antibiotic U-59,761 can be used in various environments to eradicate or control such bacteria.

    摘要翻译: 新颖的抗生素U-59,761可在控制条件下使用微生物酵母多孢菌菌株367,NRRL 12045的生物学纯培养物在发酵过程中生产。该抗生素对各种微生物有活性,例如金黄色葡萄球菌,化脓性链球菌,肺炎克雷伯杆菌 ,鸟分枝杆菌(Mycobacterium avium)和脆弱拟杆菌(Bacteroides fragilis)。 因此,抗生素U-59,761可用于各种环境以消除或控制这些细菌。

    Antibiotic berninamycin and process for making same
    4.
    发明授权
    Antibiotic berninamycin and process for making same 失效
    抗生素BERNINAMYCIN及其制备方法

    公开(公告)号:US3689639A

    公开(公告)日:1972-09-05

    申请号:US3689639D

    申请日:1969-01-23

    IPC分类号: A61K21/00

    CPC分类号: C12P1/06 Y10S435/886

    摘要: Antibiotic berninamycin producible by culturing Streptomyces bernensis Dietz, sp. nov., in an aqueous nutrient medium. Berninamycin inhibits the growth of Bacillus subtilis and can be used to control slime and corrosion in petroleum products caused by this bacterium.

    摘要翻译: 通过培养链霉菌(Streptomyces bernensis Dietz)生产的抗生素贝尔霉素 nov。,在含水营养培养基中。 贝尼霉素抑制枯草芽孢杆菌的生长,可用于控制由该细菌引起的石油产品中的粘液和腐蚀。

    Composition of matter and process
    5.
    发明授权
    Composition of matter and process 失效
    物质和过程的组成

    公开(公告)号:US4427776A

    公开(公告)日:1984-01-24

    申请号:US304393

    申请日:1981-09-21

    IPC分类号: C12P1/06 A61K35/00

    CPC分类号: C12P1/06

    摘要: Novel antibiotic U-64,815 producible in a fermentation under controlled conditions using a biologically pure culture of the microorganism Streptomyces microspinus, NRRL 12524. This antibiotic is active against various Gram-positive bacteria, for example, Staphylococcus aureus. It is also active against Haemophilus influenzae. Thus, antibiotic U-64,815 can be used in various environments to eradicate or control such bacteria.

    摘要翻译: 新型抗生素U-64,815可在受控条件下使用微生物链霉菌Streptomyces microinus NRRL 12524的生物学纯培养物在发酵过程中生产。该抗生素对各种革兰氏阳性菌(例如金黄色葡萄球菌)具有活性。 它也对抗流感嗜血杆菌活跃。 因此,抗生素U-64,815可用于各种环境以消除或控制这些细菌。

    Antibiotic composition of matter
    7.
    发明授权
    Antibiotic composition of matter 失效
    物质的抗生素组成

    公开(公告)号:US4351769A

    公开(公告)日:1982-09-28

    申请号:US180529

    申请日:1980-08-25

    摘要: Novel antibiotic U-61,732 producible in a fermentation under controlled conditions using a biologically pure culture of the microorganism Saccharopolyspora hirsuta strain 367, NRRL 12045. This antibiotic is active against gram-positive bacteria, for example, Staphylococcus aureus. Also disclosed are the 11-acyl esters of U-61,732. Thus, these compounds can be used in various environments to eradicate or control such bacteria.

    摘要翻译: 新颖的抗生素U-61,732可以在控制条件下使用微生物酵母多孢菌菌株367,NRRL 12045的生物学纯培养物进行发酵。该抗生素对革兰氏阳性细菌例如金黄色葡萄球菌是有活性的。 还公开了U-61,732的11-酰基酯。 因此,这些化合物可用于各种环境以消除或控制这些细菌。

    Saccharopolyspora culture
    8.
    发明授权
    Saccharopolyspora culture 失效
    酵母多孢菌培养

    公开(公告)号:US4321329A

    公开(公告)日:1982-03-23

    申请号:US194635

    申请日:1980-10-06

    IPC分类号: C12P1/06 C12N1/20

    CPC分类号: C12R1/01 C12P1/06

    摘要: A process for preparing the antibiotic U-59,760. The process is a microbiological process using a biologically pure culture of the novel microbe Saccharopolyspora hirsuta strain 367, NRRL 12045. The antibiotic produced by the process is active against various microorganisms, for example, Staphylococcus aureus, Streptococcus pyogenes, and Klebsiella pneumoniae. Thus, antibiotic U-59,760 can be used in various environments to eradicate or control such bacteria.

    摘要翻译: 制备抗生素U-59,760的方法。 该过程是使用新型微生物酵母多孢菌菌株367,NRRL 12045的生物纯培养物的微生物过程。由该方法产生的抗生素对各种微生物有活性,例如金黄色葡萄球菌,化脓性链球菌和肺炎克雷伯杆菌。 因此,抗生素U-59,760可用于各种环境中以消除或控制这些细菌。

    Process for producing antibiotic using saccharopolyspora
    9.
    发明授权
    Process for producing antibiotic using saccharopolyspora 失效
    使用糖酵母生产抗生素的方法

    公开(公告)号:US4293651A

    公开(公告)日:1981-10-06

    申请号:US81211

    申请日:1979-10-02

    IPC分类号: C12P1/06

    CPC分类号: C12R1/01 C12P1/06 Y10S435/822

    摘要: A process for preparing the antibiotic U-59,760. The process is a microbiological process using a biologically pure culture of the novel microbe Saccharopolyspora hirsuta strain 367, NRRL 12045. The antibiotic produced by the process is active against various microorganisms, for example, Staphylococcus aureus, Streptococcus pyogenes, and Klebsiella pneumoniae. Thus, antibiotic U-59,760 can be used in various environments to eradicate or control such bacteria.

    摘要翻译: 制备抗生素U-59,760的方法。 该过程是使用新型微生物酵母多孢菌菌株367,NRRL 12045的生物纯培养物的微生物过程。由该方法产生的抗生素对各种微生物有活性,例如金黄色葡萄球菌,化脓性链球菌和肺炎克雷伯杆菌。 因此,抗生素U-59,760可用于各种环境中以消除或控制这些细菌。

    Process for preparing lincomycin
    10.
    发明授权
    Process for preparing lincomycin 失效
    林可霉素的制备方法

    公开(公告)号:US4271266A

    公开(公告)日:1981-06-02

    申请号:US477766

    申请日:1974-06-10

    CPC分类号: C07H15/16 Y10S435/886

    摘要: Microbiological process for preparing the antibiotic lincomycin at temperatures ranging from 18.degree. C. to 45.degree. C. using the newly discovered microorganism Streptomyces vellosus. The subject process advantageously results in the preparation of lincomycin without the concomitant production of lincomycin B (4'-depropyl-4'-ethyllincomycin). The absence of lincomycin B production results in increased lincomycin recovery efficiency.

    摘要翻译: 使用新发现的微生物链霉菌(Streptomyces vellosus)在18℃至45℃的温度范围内制备抗生素林可霉素的微生物过程。 本发明方法有利地导致林可霉素的制备,而不伴随产生林可霉素B(4'-去丙基-4'-乙基林霉素)。 林可霉素B生产的缺乏导致林可霉素回收效率提高。