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公开(公告)号：US20130289278A1
公开(公告)日：2013-10-31
申请号：US13834106
申请日：2013-03-15
Applicant: Kelly Sullivan Kraft , John J. Freeman , Paul Serwinski , Vinnie Pavia , Otto Phanstiel, IV , Navneet Kaur
Inventor： Kelly Sullivan Kraft , John J. Freeman , Paul Serwinski , Vinnie Pavia , Otto Phanstiel, IV , Navneet Kaur
IPC: C07D241/08 , C07C67/39 , C07C201/12
CPC classification number: C07D241/08 , C07C67/30 , C07C67/39 , C07C201/12 , C07C69/60 , C07C205/43
Abstract: Disclosed embodiments relate to improved methods for the synthesis of activated fumarate intermediates and their use in chemical synthesis. Disclosed embodiments describe the synthesis of activated fumarate esters including those derived from activating groups including: 4-nitrophenyl, diphenylphosphoryl azide, pivaloyl chloride, chlorosulfonyl isocyanate, p-nitrophenol, MEF, trifluoroacetyl and chlorine, for example, ethyl fumaroyl chloride and the subsequent use of the activated ester in situ. Further embodiments describe the improved synthesis of substituted aminoalkyl-diketopiperazines from unisolated and unpurified intermediates allowing for improved yields and reactor throughput.
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公开(公告)号：US07129274B1
公开(公告)日：2006-10-31
申请号：US10129467
申请日：2000-11-06
Applicant: Andrea Leone-Bay , Kelly Kraft , Destardi Moye-Sherman , David Gschneidner , Maria A. P. Boyd , Puchun Liu , Pingwah Tang , Jun Liao , John J. Freeman, Jr. , John E. Smart
Inventor： Andrea Leone-Bay , Kelly Kraft , Destardi Moye-Sherman , David Gschneidner , Maria A. P. Boyd , Puchun Liu , Pingwah Tang , Jun Liao , John J. Freeman, Jr. , John E. Smart
CPC classification number: C07C59/64 , C07C59/42 , C07C59/56 , C07C59/74 , C07C59/84 , C07C59/90 , C07C63/14
Abstract: Phenoxy carboxylic acid compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well.
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公开(公告)号：US5738794A
公开(公告)日：1998-04-14
申请号：US726156
申请日：1996-10-03
Applicant: Joseph J. Mallon , Raymond S. Farinato , Louis Rosati , John J. Freeman, Jr.
Inventor： Joseph J. Mallon , Raymond S. Farinato , Louis Rosati , John J. Freeman, Jr.
CPC classification number: C02F1/56 , C02F1/5245 , C02F11/14 , Y10S106/90 , Y10S210/928 , Y10S47/10 , Y10S71/903
Abstract: Compositions of precipitated cationic polymers containing mixtures of certain salts as well as processes for making and using the same are disclosed.
Abstract translation: 公开了含有某些盐的混合物的沉淀的阳离子聚合物的组合物以及其制备和使用方法。
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4.发明授权Phenoxy carboxylic acid compounds and compositions for delivering active agents 有权苯氧基羧酸化合物和用于递送活性剂的组合物公开(公告)号：US08410309B2
公开(公告)日：2013-04-02
申请号：US11458331
申请日：2006-07-18
Applicant: Andrea Leone-Bay , Kelly Kraft , Destardi Moye-Sherman , David Gschneidner , Maria Aurora P. Boyd , Puchun Liu , Pingwah Tang , Jun Liao , John Smart , John J. Freeman, Jr.
Inventor： Andrea Leone-Bay , Kelly Kraft , Destardi Moye-Sherman , David Gschneidner , Maria Aurora P. Boyd , Puchun Liu , Pingwah Tang , Jun Liao , John Smart , John J. Freeman, Jr.
CPC classification number: C07C59/64 , C07C59/42 , C07C59/56 , C07C59/74 , C07C59/84 , C07C59/90 , C07C63/14
Abstract: Phenoxy carboxylic acid compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well.
Abstract translation: 提供了苯氧基羧酸化合物和用于递送活性剂的组合物。 也提供给药和制备方法。
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公开(公告)号：US06693208B2
公开(公告)日：2004-02-17
申请号：US10168275
申请日：2002-07-15
Applicant: David Gscheidner , Andrea Leone-Bay , Eric Wang , John J. Freeman , Doris C. O'Toole , Lynn Shields
Inventor： David Gscheidner , Andrea Leone-Bay , Eric Wang , John J. Freeman , Doris C. O'Toole , Lynn Shields
IPC: C07C2300
CPC classification number: C07C235/60 , C07C235/64 , C07C235/84 , C07C237/42
Abstract: Amino acid derivative as carrier compounds and compositions which are useful in the delivery of active agents are provided. The active agents can be a peptide, mucopolysaccharide, carbohydrate, or lipid. Methods of administration, including oral administration, and preparation are provided as well.
Abstract translation: 提供了可用于递送活性剂的载体化合物和组合物的氨基酸衍生物。 活性剂可以是肽，粘多糖，碳水化合物或脂质。 还提供给药方法，包括口服给药和制备。
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Patent Agency Ranking
公开(公告)号：US5934839A
公开(公告)日：1999-08-10
申请号：US968313
申请日：1997-11-12
Applicant: Joseph J. Mallon , Raymond S. Farinato , Louis Rosati , John J. Freeman, Jr.
Inventor： Joseph J. Mallon , Raymond S. Farinato , Louis Rosati , John J. Freeman, Jr.
CPC classification number: C02F1/56 , C02F1/5245 , C02F11/14 , Y10S106/90 , Y10S210/928 , Y10S47/10 , Y10S71/903
Abstract: Compositions of precipitated cationic polymers containing mixtures of certain salts as well as processes for making and using the same are disclosed.
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公开(公告)号：US5779396A
公开(公告)日：1998-07-14
申请号：US726158
申请日：1996-10-03
Applicant: Joseph J. Mallon , Raymond S. Farinato , Louis Rosati , John J. Freeman, Jr.
Inventor： Joseph J. Mallon , Raymond S. Farinato , Louis Rosati , John J. Freeman, Jr.
CPC classification number: C02F1/56 , C09K17/18 , C09K17/48 , Y10S106/90 , Y10S71/903
Abstract: Compositions of precipitated anionic polymers containing mixtures of cationic organic salts and kosmotropic salts as well as processes for making and using the same to condition soil are disclosed.
Abstract translation: 公开了含有阳离子有机盐和亲水性盐的混合物的沉淀阴离子聚合物的组合物以及制备和使用它们来调节土壤的方法。
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公开(公告)号：US5733462A
公开(公告)日：1998-03-31
申请号：US720830
申请日：1996-10-03
Applicant: Joseph J. Mallon , Raymond S. Farinato , Louis Rosati , John J. Freeman, Jr.
Inventor： Joseph J. Mallon , Raymond S. Farinato , Louis Rosati , John J. Freeman, Jr.
CPC classification number: C02F1/56 , C02F1/5245 , C02F11/14 , C09K17/40 , Y10S106/90 , Y10S210/928 , Y10S71/903
Abstract: Compositions of precipitated cationic polymers containing mixtures of certain salts as well as processes for making and using the same are disclosed.
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公开(公告)号：US5725779A
公开(公告)日：1998-03-10
申请号：US723628
申请日：1996-10-03
Applicant: Joseph J. Mallon , Raymond S. Farinato , Louis Rosati , John J. Freeman, Jr.
Inventor： Joseph J. Mallon , Raymond S. Farinato , Louis Rosati , John J. Freeman, Jr.
CPC classification number: C08J3/14 , C02F1/56 , C09K17/18 , C09K17/48 , D21C9/005 , D21H21/10 , C08J2300/14 , Y10S210/928
Abstract: Compositions of precipitated anionic polymers containing mixtures of certain salts as well as processes for making and using the same are disclosed.
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公开(公告)号：US4699896A
公开(公告)日：1987-10-13
申请号：US774477
申请日：1985-09-10
Applicant: Kenneth S. W. Sing , Frederick G. R. Gimblett , John J. Freeman
Inventor： Kenneth S. W. Sing , Frederick G. R. Gimblett , John J. Freeman
CPC classification number: B01J21/18 , B01J23/04 , C01B31/089 , C01B31/125 , D01F11/124 , D01F9/16
Abstract: A method of preparing a fibrous activated carbon including the steps of carbonizing and activating cellulose fibre at temperatures between 200.degree. C. and 1000.degree. C. in an inert atmosphere, characterized in that, prior to activation, the fibre is impregnated with an impregnating material comprising, in the form of one or more compounds, boron and at least one alkali metal.
Abstract translation: 一种制备纤维活性炭的方法，包括在惰性气氛中在200℃至1000℃之间的温度下碳化和活化纤维素纤维的步骤，其特征在于，在活化之前，用浸渍材料 以一种或多种化合物的形式包含硼和至少一种碱金属。
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