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公开(公告)号：US4413057A
公开(公告)日：1983-11-01
申请号：US343305
申请日：1981-03-16
CPC分类号： A61K39/092 , C12P19/26
摘要： Group B Streptococcus type-specific polysaccharides types I.sub.1, I.sub.b, II and III have been obtained from strains grown in a modified soy bean and yeast medium. These polysaccharides are useful as active or passive streptococcal vaccines.
摘要翻译： B族链球菌型特异性多糖类型I1，Ib，II和III已经从在改良大豆和酵母培养基中生长的菌株获得。 这些多糖可用作活性或被动链球菌疫苗。
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公开(公告)号：US4335101A
公开(公告)日：1982-06-15
申请号：US372137
申请日：1973-06-21
IPC分类号： A23G3/00 , A23G3/36 , A23G4/00 , A23G4/12 , A23L29/00 , A61K8/66 , A61Q11/00 , C12N9/24 , A61K7/28
CPC分类号： A23G3/366 , A23G3/368 , A23G4/123 , A23L29/06 , A61K8/66 , A61Q11/00 , C12N9/2428 , C12Y302/01059 , C12Y302/01071 , C12Y302/01084
摘要： Enzymes called cariogenanases, elaborated by microorganisms are isolated and characterized as polysaccharases capable of degrading cariogenan, a newly discovered glucan of dental plaque composed of .alpha.-(1.fwdarw.3) and .alpha.-(1.fwdarw.2) linkages. The enzymes are isolable from culture broths of various organisms by protein precipitation methods, and have utility as an anti-dental plaque agent, either as the sole enzymatic agent or in combination with dextranases and/or plaque dispersing proteases.
摘要翻译： 由微生物制备的称为致癌物的酶被分离并表征为能够降解由α-（1-> 3）和α-（1-> 2）键组成的牙斑的新近发现的葡聚糖的焦糖的多糖酶。 酶可以通过蛋白质沉淀方法从各种生物的培养液中分离，并且作为唯一的酶剂或与葡聚糖酶和/或斑块分散蛋白酶组合可用作抗牙菌斑剂。
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公开(公告)号：US4430322A
公开(公告)日：1984-02-07
申请号：US372509
申请日：1982-04-28
CPC分类号： A61K31/715 , A61K8/73 , A61Q11/00 , C12P19/18
摘要： Certain glucans modify the biosynthetic route of extracellular polysaccharides involved in dental plaque development causing critical loss of adhesiveness. They interfere with the biosynthesis of cell-bound polysaccharides reducing and preventing agglutination of cells. They thus aid in the prevention of dental plaque formation or concomitant dental caries and periodontal disease.
摘要翻译： 某些葡聚糖修饰涉及牙斑发育的细胞外多糖的生物合成途径导致粘合性的严重丧失。 它们干扰细胞结合多糖的生物合成，从而减少和预防细胞的凝集。 因此它们有助于预防牙斑形成或伴随的龋齿和牙周病。
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公开(公告)号：US4340673A
公开(公告)日：1982-07-20
申请号：US205030
申请日：1980-11-07
IPC分类号： A61K8/73 , A61K31/715 , A61Q11/00 , C12P19/18 , C12P19/04
CPC分类号： A61K31/715 , A61K8/73 , A61Q11/00 , C12P19/18 , Y10S435/885
摘要： Certain glucans modify the biosynthetic route of extracellular polysaccharides involved in dental plaque development causing critical loss of adhesiveness. They interfere with the biosynthesis of cell-bound polysaccharides reducing and preventing agglutination of cells. They thus aid in the prevention of dental plaque formation or concomitant dental caries and periodontal disease.
摘要翻译： 某些葡聚糖修饰涉及牙斑发育的细胞外多糖的生物合成途径导致粘合性的严重丧失。 它们干扰细胞结合多糖的生物合成，从而减少和预防细胞的凝集。 因此它们有助于预防牙斑形成或伴随的龋齿和牙周病。
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