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公开(公告)号：US4208169A
公开(公告)日：1980-06-17
申请号：US795561
申请日：1977-05-10
CPC分类号： F04D29/245
摘要： A radial or semiaxial impeller for centrifugal pumps has an annulus of vanes whose inlet edges are disposed at the periphery of a circle and are bounded by convex transition surfaces having small radii of curvature. The inner portions of the suction sides of vanes are bounded by flat or slightly curved surfaces which merge gradually into concave surfaces bounding the outer portions of the respective suction sides. The length of each flat or slightly curved surface is between 3 millimeters and the vane pitch. The ratio of the radii of curvature of transition surfaces at the inlet edges of the vanes to the vane pitch is between 0.0035 and 0.04 and/or the ratio of these radii to the average thickness of the inlet portion of a conventional vane is between 0.04 and 0.50. Such construction of the vanes reduces the likelihood of excessive erosion as a result of cavitation.
摘要翻译： 用于离心泵的径向或半轴叶轮具有叶片环，其入口边缘设置在圆周边并且由具有小曲率半径的凸过渡表面限定。 叶片的吸力侧的内部由平坦或略微弯曲的表面限定，该表面逐渐合并在与相应吸力侧的外部部分相邻的凹面中。 每个平坦或略微弯曲的表面的长度在3毫米和叶片间距之间。 叶片的入口边缘处的过渡表面的曲率半径与叶片间距的比率在0.0035和0.04之间，和/或这些半径与常规叶片的入口部分的平均厚度之比在0.04和 0.50。 叶片的这种构造减少了由于空化引起的过度侵蚀的可能性。
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2.发明授权
公开(公告)号：US4153216A
公开(公告)日：1979-05-08
申请号：US869947
申请日：1978-01-16
CPC分类号： B23D31/04
摘要： An apparatus for chip removal and chip receiving when trimming metal bands, which includes an automatically driven and self-controlling winding-up device for tautly winding-up the seam chip cut off from a metal band being trimmed. The apparatus furthermore includes a chip guiding device reciprocable alongside the chip winding-up region for guiding engagement with the chip being fed to the winding-up device.
摘要翻译： 一种用于在修整金属带时进行芯片去除和芯片接收的装置，其包括自动驱动和自动控制的清理装置，用于将被切割的金属带切断的接缝芯片紧紧地卷起。 该装置还包括可沿着芯片卷绕区域往复运动的芯片引导装置，用于引导与馈送到卷绕装置的芯片的接合。
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公开(公告)号：US4564334A
公开(公告)日：1986-01-14
申请号：US604075
申请日：1984-04-26
IPC分类号： F04D29/44
CPC分类号： F04D29/445
摘要： The follow-up guide wheels of a multistage centrifugal pump define flow paths whose cross-sectional area increases exclusively in the axial direction of the respective stages, or axially and radially inwardly, to thus allow for a reduction of the outer diameters of the guide wheels without reducing the efficiency of the pump.
摘要翻译： 多级离心泵的后续导轮限定了流路，其横截面积仅在相应级的轴向方向上增加，或者轴向和径向向内增加，从而允许导轮的外径减小 而不降低泵的效率。
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公开(公告)号：US4383800A
公开(公告)日：1983-05-17
申请号：US226751
申请日：1981-01-21
CPC分类号： F04D29/426
摘要： The double volute casing of a centrifugal pump has a main portion which has first and second volutes extending along arcs of not more than 180 degrees. The outer diameter of the main portion equals or approximates the outer diameter of the end of the first volute, and such end is adjacent to the start of the second volute whose end communicates with an outlet nozzle of the main portion. The latter has two channels which flank the second volute and extend between the end of the first volute and the outlet nozzle. The inner sides of the channels are open and face the axial passage of the main portion. Such inner sides are sealed from the axial passage by tubular inserts which are installed in and are separably fastened to the main portion of the casing. The passage receives a single-suction or a double-suction impeller or a stationary guide wheel which is located downstream of the impeller. The main portion of the casing is a one-piece casting.
摘要翻译： 离心泵的双涡壳体具有主要部分，其具有沿着不超过180度的弧线延伸的第一和第二蜗壳。 主要部分的外径等于或近似于第一蜗壳的端部的外径，并且该端部与第二蜗壳的开始部相邻，其端部与主要部分的出口喷嘴连通。 后者具有在第二蜗壳侧面并且在第一蜗壳的端部和出口喷嘴之间延伸的两个通道。 通道的内侧是敞开的并面向主要部分的轴向通道。 这样的内侧通过管状插入件与轴向通道密封，管状插入件安装在壳体的主要部分中且可分离地固定在壳体的主要部分上。 该通道接收位于叶轮下游的单吸或双吸叶轮或固定导轮。 外壳的主要部分是一体式铸件。
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公开(公告)号：US4406583A
公开(公告)日：1983-09-27
申请号：US225007
申请日：1981-01-14
CPC分类号： F04D29/426
摘要： A centrifugal pump comprises a casing which has two volutes disposed substantially diametrically opposite each other in such a way that the end of the first volute is adjacent to the start of the second volute. The outer diameter of the casing approximates or equals the diameter of the first volute in the region of the end of the first volute. This contributes to compactness of the casing. The volutes surround a rotary impeller or a guide wheel which is installed in the casing downstream of the impeller. Each volute extends along an arc of at most 180 degrees. The casing can have one or more elongated channels extending from the end of the first volute, along the second volute, and to a common outlet nozzle for both volutes.
摘要翻译： 离心泵包括壳体，壳体具有两个基本上沿径向相对设置的蜗壳，使得第一蜗壳的端部与第二蜗壳的起始点相邻。 外壳的外径近似于或等于第一个蜗壳末端区域内的第一个蜗壳的直径。 这有助于壳体的紧凑性。 蜗壳围绕安装在叶轮下游的壳体中的旋转叶轮或导轮。 每个蜗壳沿着最多180度的弧线延伸。 壳体可以具有从第一蜗壳的端部沿着第二蜗壳延伸的一个或多个细长通道，以及用于两个蜗壳的公共出口喷嘴。
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公开(公告)号：US4171370A
公开(公告)日：1979-10-16
申请号：US839487
申请日：1977-10-04
IPC分类号： A61K31/13 , A61K20060101 , A61K31/135 , A61K31/165 , A61K31/36 , A61P3/06 , A61P7/02 , A61P9/00 , A61P9/06 , A61P9/12 , A61P25/00 , A61P25/02 , C07C20060101 , C07C67/00 , C07C213/00 , C07C217/32 , C07D317/06 , C07D317/54 , C07D317/58
CPC分类号： C07D317/58 , C07D303/24 , Y10S514/821
摘要： New phenoxy-amino-propanols of formula ##STR1## wherein R.sup.1 is alkenyl, alkynyl, alkoxyalkyl or alkenyloxyalkyl with 2-6 C atoms in each case or cycloalkyl with 3-8 C atoms; and R.sup.2 is alkyl or hydroxyalkyl with 1-6 C atoms in each case, cycloalkyl with 3-8 C atoms, aralkyl or aralkyl wherein the aryl radical is mono- to tri-substituted by alkyl, alkoxy, OH, F and/or Cl or mono-substituted by methylenedioxy, with a total of 7-15 C atoms in each case, and the physiologically acceptable acid addition salts thereof, exhibit various pharmacological properties including isoprenaline-antagonism on the heart rate and blood pressure.
摘要翻译： 其中R 1是具有2-6个C原子的链烯基，炔基，烷氧基烷基或烯氧基烷基，或者具有3-8个C原子的环烷基的新的苯氧基 - 氨基 - 丙醇; 并且R 2是每种情况下具有1-6个C原子的烷基或羟基烷基，具有3-8个C原子的环烷基，芳烷基或芳烷基，其中所述芳基被烷基，烷氧基，OH，F和/或Cl单取代至三取代 或者由亚甲二氧基单取代，在每种情况下总共具有7-15个C原子，并且其生理上可接受的酸加成盐具有包括对心率和血压的异丙肾上腺素拮抗作用的各种药理学性质。
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公开(公告)号：US3989833A
公开(公告)日：1976-11-02
申请号：US520888
申请日：1974-11-04
IPC分类号： C07D473/34 , A61K20060101 , A61K31/52 , C07D20060101 , C07D235/00 , C07D239/00
摘要： Adenine derivatives of the formula ##SPC1##Wherein R is phenyl or thienyl, and the physiologically acceptable acid addition salts thereof, possess, with good compatibility, cardio-active properties and are produced by the reaction of a purine derivative of the formula ##SPC2##Wherein X is F, Cl, Br, I, SR.sub.1, SOR.sub.1, SO.sub.2 R.sub.1 or OSi(CH.sub.3).sub.3, R.sub.1 being alkyl of 1-4 carbon atoms, phenyl or benzyl, with an amine of the formula ##SPC3##Wherein R has the values given above, or a salt thereof.
摘要翻译： 式WHEREIN R是苯基或噻吩基的腺嘌呤衍生物及其生理学上可接受的酸加成盐具有良好的相容性，具有心脏活性的特性，并且通过式WHEREIN X的嘌呤衍生物与F，Cl ，Br，I，SR1，SOR1，SO2R1或OSi（CH3）3，R1为1-4个碳原子的烷基，苯基或苄基，与式WHEREIN R具有上述给出的值或其盐。
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8.发明授权1-Aryloxy-3-nitratoalkylamino-2-propanols and use as .beta.-receptor blocker 失效1-芳氧基-3-硝基烷基氨基-2-丙醇，用作β受体阻滞剂
公开(公告)号：US4288452A
公开(公告)日：1981-09-08
申请号：US10781
申请日：1979-02-09
IPC分类号： A61K31/13 , A61K31/135 , A61K31/165 , A61K31/40 , A61K31/403 , A61K31/404 , A61K31/47 , A61P25/02 , C07C67/00 , C07C213/00 , C07C217/30 , C07C217/32 , C07C231/00 , C07C231/12 , C07C233/25 , C07C253/00 , C07C255/54 , C07C313/00 , C07C319/20 , C07C323/11 , C07D209/08 , C07D209/30 , C07D209/32 , C07D209/88 , C07D215/20 , A61K31/21 , A61K31/275 , C07C77/02
CPC分类号： C07D209/08
摘要： Compounds of the formulaAr--O--CH.sub.2 --CHOH--CH.sub.2 --NH--RwhereinAr is phenyl; phenyl monosubstituted or polysubstituted by halogen, cyano, acylamino (in which the acyl group has 1-7 carbon atoms), alkanoyl of 1-4 carbon atoms, alkyl (in which the chain can be interrupted by 1 or 2 oxygen atoms or by one sulfur atom and/or in which a multiple bond can be present) of a total of 1-10 carbon atoms, cycloalkyl of 3-8 carbon atoms, and/or cycloalkoxy of 3-8 carbon atoms; naphthyl; indanyl; indenyl; tetralyl; indolyl; indolyl monosubstituted or polysubstituted by alkyl, each of 1-4 carbon atoms; carbazolyl; or 1,2,3,4-tetrahydro-2-oxoquinolyl; andR is nitratoalkyl of 2-10 carbon atoms,and the physiologically acceptable acid addition salts thereof have valuable pharmacological properties, e.g., which make them useful for prophylaxis and treatment of heart problems, e.g., as .beta.-receptor blockers.
摘要翻译： 式Ar-O-CH2-CHOH-CH2-NH-R的化合物，其中Ar是苯基; 被卤素，氰基，酰基氨基（其中酰基具有1-7个碳原子）单取代或多取代的苯基，1-4个碳原子的烷酰基，烷基（其中链可以被1或2个氧原子或一个 总共1-10个碳原子的硫原子和/或多重键可以存在），和3-8个碳原子的环烷基和/或3-8个碳原子的环烷氧基; 萘基; 茚满基 茚基; 四氢萘 吲哚基 由1-4个碳原子的烷基单取代或多取代的吲哚基; 咔唑基; 或1,2,3,4-四氢-2-氧代喹啉基; 并且R是2-10个碳原子的硝基烷基，并且其生理上可接受的酸加成盐具有有价值的药理学性质，例如使其可用于心脏问题的预防和治疗，例如作为β-受体阻断剂。
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公开(公告)号：US4258062A
公开(公告)日：1981-03-24
申请号：US43925
申请日：1979-05-30
IPC分类号： A61K31/13 , A61K20060101 , A61K31/135 , A61K31/165 , A61K31/36 , A61P3/06 , A61P7/02 , A61P9/00 , A61P9/06 , A61P9/12 , A61P25/00 , A61P25/02 , C07C20060101 , C07C67/00 , C07C213/00 , C07C217/32 , C07D317/06 , C07D317/54 , C07D317/58 , C07C93/06
CPC分类号： C07D317/58 , C07D303/24 , Y10S514/821
摘要： New phenoxy-amino-propanols of formula ##STR1## wherein R.sup.1 is alkenyl, alkynyl, alkoxyalkyl or alkenyloxyalkyl with 2-6 C atoms in each case or cycloalkyl with 3-8 C atoms; and R.sup.2 is alkyl or hydroxyalkyl with 1-6 C atoms in each case, cycloalkyl with 3-8 C atoms, aralkyl or aralkyl wherein the aryl radical is mono- to tri-substituted by alkyl, alkoxy, OH, F and/or Cl or mono-substituted by methylenedioxy, with a total of 7-15 C atoms in each case, and the physiologically acceptable acid addition salts thereof, exhibit various pharmacological properties including isoprenaline-antagonism on the heart rate and blood pressure.
摘要翻译： 其中R 1是具有2-6个C原子的链烯基，炔基，烷氧基烷基或烯氧基烷基，或者具有3-8个C原子的环烷基的新的苯氧基 - 氨基 - 丙醇; 并且R 2是每种情况下具有1-6个C原子的烷基或羟基烷基，具有3-8个C原子的环烷基，芳烷基或芳烷基，其中所述芳基被烷基，烷氧基，OH，F和/或Cl单取代至三取代 或者由亚甲二氧基单取代，在每种情况下总共具有7-15个C原子，并且其生理上可接受的酸加成盐具有包括对心率和血压的异丙肾上腺素拮抗作用的各种药理学性质。
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10.发明授权1(3,4,5-Trimethoxybenzamido methyl) tetrahydro isoquinoline derivatives and a process for their production 失效1（3,4,5-三甲氧基苯甲酰氨基甲基）四氢异喹啉衍生物及其制备方法
公开(公告)号：US3985881A
公开(公告)日：1976-10-12
申请号：US530551
申请日：1974-12-09
IPC分类号： C07D217/12 , C07D217/14 , C07D217/26
CPC分类号： C07D217/26 , C07D217/14
摘要： Novel isoquinoline derivatives of the formula ##SPC1##Wherein R.sub.1 is H or, together with R.sub.2, a C--N bond; R.sub.2 is H, R.sub.8 or, together with R.sub.1, a C--N bond; R.sub.3 is H, methyl or ethyl; R.sub.4 and R.sub.5 each are H or collectively a C--C bond; and R.sub.6 and R.sub.7 each are H or methoxy; R.sub.8 being acyl of 1-10 carbon atoms or alkyl of 1-17 carbon atoms optionally mono- or polysubstituted by phenyl, OH, ArCOO--, ArCONH--, piperidino, 3,4-dehydropiperidino, morpholino, carboxy, carbomethoxy and/or carbethoxy, Ar being 3,4,5-trimethoxyphenyl; and the physiologically acceptable acid addition salts and quaternary ammonium salts thereof, have cardiovascular activity and can be prepared by acylating a corresponding primary amine lacking the COAr group with 3,4,5-trimethoxybenzoic acid or a functional derivative thereof.
摘要翻译： 式WHEREIN R1的新型异喹啉衍生物是H或与R2一起形成C-N键; R2是H，R8或与R1一起形成C-N键; R3是H，甲基或乙基; R4和R5各自为H或共同为C-C键; R6和R7各自为H或甲氧基; R8是1-10个碳原子的酰基或1-17个碳原子的烷基，任选被苯基，OH，ArCOO - ，ArCONH-，哌啶子基，3,4-脱氢哌啶子基，吗啉代，羧基，甲酯基和/或乙氧基乙氧基 Ar为3,4,5-三甲氧基苯基; 并且其生理上可接受的酸加成盐和季铵盐具有心血管活性，并且可以通过用3,4,5-三甲氧基苯甲酸或其功能性衍生物酰化相应的缺少COAr基团的伯胺来制备。
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