公开(公告)号：US20100160750A1

公开(公告)日：2010-06-24

申请号：US12498360

申请日：2009-07-06

申请人： Steven C. White ,  John Heanue ,  Kate Bechtel

发明人： Steven C. White ,  John Heanue ,  Kate Bechtel

IPC分类号： A61B5/1455

CPC分类号： A61B5/1455 ,  A61B5/0059 ,  A61B5/0062 ,  A61B5/0075 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/441

摘要： An apparatus and method for acquiring and analyzing a spectroscopic sample for a substance from a sampling region of the tissue of a person at an interstitial region between the fingers of the person, by way of a probe and a spectroscopic detector for radiating the interstitial region with electromagnetic radiation and analyzing a diffuse-reflectance signal obtained from the tissue at the sampling region. The apparatus preferably also incorporates a biometric sensor to perform a verification of the person.

摘要翻译： 一种用于通过探针和用于将间质区域辐射的分光检测器从人的手指之间的间隙区域中的人的组织的取样区域获取和分析物质的光谱样品的装置和方法， 电磁辐射，并分析从采样区域的组织获得的漫反射信号。 该装置优选还包括用于执行人的验证的生物特征传感器。

公开(公告)号：US09103793B2

公开(公告)日：2015-08-11

申请号：US11492214

申请日：2006-07-24

申请人： Kate Bechtel ,  Wei-Chuan Shih ,  Michael S. Feld

发明人： Kate Bechtel ,  Wei-Chuan Shih ,  Michael S. Feld

IPC分类号： A61B5/1455 ,  G01N21/65 ,  A61B5/145

CPC分类号： A61B5/1455 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1495 ,  A61B2560/0223 ,  G01N21/65

摘要： The present invention relates to systems and methods for the measurement of analytes such as glucose. Raman and reflectance spectroscopy are used to measure a volume, of material such as a blood sample or tissue within a subject and determine a concentration of a blood analyte based thereon. The present invention further relates to a calibration method, constrained regularization (CR), and demonstrates its use for analyzing spectra including, for example, the measurement glucose concentrations using transcutaneous Raman spectroscopy.

摘要翻译： 本发明涉及用于测量诸如葡萄糖的分析物的系统和方法。 使用拉曼和反射光谱来测量受试者内的材料，例如血液样本或组织的体积，并且基于此测定血液分析物的浓度。 本发明还涉及校准方法，约束正则化（CR），并证明其用于分析光谱的用途，包括例如使用经皮拉曼光谱测量葡萄糖浓度。

公开(公告)号：US20070049809A1

公开(公告)日：2007-03-01

申请号：US11492214

申请日：2006-07-24

申请人： Kate Bechtel ,  Wei-Chuan Shih ,  Michael Feld

发明人： Kate Bechtel ,  Wei-Chuan Shih ,  Michael Feld

IPC分类号： A61B5/00

CPC分类号： A61B5/1455 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1495 ,  A61B2560/0223 ,  G01N21/65

摘要： The present invention relates to systems and methods for the measurement of analytes such as glucose. Raman and reflectance spectroscopy are used to measure a volume, of material such as a blood sample or tissue within a subject and determine a concentration of a blood analyte based thereon. The present invention further relates to a calibration method, constrained regularization (CR), and demonstrates its use for analyzing spectra including, for example, the measurement glucose concentrations using transcutaneous Raman spectroscopy.

摘要翻译： 本发明涉及用于测量诸如葡萄糖的分析物的系统和方法。 使用拉曼和反射光谱来测量受试者内的材料，例如血液样本或组织的体积，并且基于此测定血液分析物的浓度。 本发明还涉及校准方法，约束正则化（CR），并证明其用于分析光谱的用途，包括例如使用经皮拉曼光谱测量葡萄糖浓度。