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公开(公告)号：US08058421B2
公开(公告)日：2011-11-15
申请号：US12689321
申请日：2010-01-19
申请人： Stephen B. Milligan , Dale Skalla , Kay Lawton
发明人： Stephen B. Milligan , Dale Skalla , Kay Lawton
CPC分类号： C12N15/8227 , C07K14/415
摘要： The present invention is directed to promoters isolated from maize and functional equivalents thereto. The promoters of the present invention have particular utility in driving root-specific expression of heterologous genes that impart increased agronomic, horticultural and/or pesticidal characteristics to a given transgenic plant. The present invention is also drawn to DNA molecules comprising the promoters of the invention and transformed plant tissues containing DNA molecules comprising a promoter of the invention operably linked to a heterologous gene or genes, and seeds thereof.
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公开(公告)号：US08058419B2
公开(公告)日：2011-11-15
申请号：US12689311
申请日：2010-01-19
申请人： Stephen B. Milligan , Dale Skalla , Kay Lawton
发明人： Stephen B. Milligan , Dale Skalla , Kay Lawton
CPC分类号： C12N15/8227 , C07K14/415
摘要： The present invention is directed to promoters isolated from maize and functional equivalents thereto. The promoters of the present invention have particular utility in driving root-specific expression of heterologous genes that impart increased agronomic, horticultural and/or pesticidal characteristics to a given transgenic plant. The present invention is also drawn to DNA molecules comprising the promoters of the invention and transformed plant tissues containing DNA molecules comprising a promoter of the invention operably linked to a heterologous gene or genes, and seeds thereof.
摘要翻译： 本发明涉及从玉米分离的启动子及其功能等同物。 本发明的启动子在驱动给定转基因植物赋予增加的农艺，园艺和/或杀虫特征的异源基因的根特异性表达方面具有特别的用途。 本发明还涉及包含本发明启动子的DNA分子和含有可操作地连接到异源基因或基因的本发明启动子的DNA分子的转化植物组织及其种子。
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公开(公告)号：US20100205693A1
公开(公告)日：2010-08-12
申请号：US12689321
申请日：2010-01-19
申请人： Stephen B. MILLIGAN , Dale SKALLA , Kay LAWTON
发明人： Stephen B. MILLIGAN , Dale SKALLA , Kay LAWTON
CPC分类号： C12N15/8227 , C07K14/415
摘要： The present invention is directed to promoters isolated from maize and functional equivalents thereto. The promoters of the present invention have particular utility in driving root-specific expression of heterologous genes that impart increased agronomic, horticultural and/or pesticidal characteristics to a given transgenic plant. The present invention is also drawn to DNA molecules comprising the promoters of the invention and transformed plant tissues containing DNA molecules comprising a promoter of the invention operably linked to a heterologous gene or genes, and seeds thereof.
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公开(公告)号：US20100205695A1
公开(公告)日：2010-08-12
申请号：US12689318
申请日：2010-01-19
申请人： Stephen B. MILLIGAN , Dale SKALLA , Kay LAWTON
发明人： Stephen B. MILLIGAN , Dale SKALLA , Kay LAWTON
CPC分类号： C12N15/8227 , C07K14/415
摘要： The present invention is directed to promoters isolated from maize and functional equivalents thereto. The promoters of the present invention have particular utility in driving root-specific expression of heterologous genes that impart increased agronomic, horticultural and/or pesticidal characteristics to a given transgenic plant. The present invention is also drawn to DNA molecules comprising the promoters of the invention and transformed plant tissues containing DNA molecules comprising a promoter of the invention operably linked to a heterologous gene or genes, and seeds thereof.
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公开(公告)号：US20050010974A1
公开(公告)日：2005-01-13
申请号：US10490147
申请日：2002-11-04
申请人： Stephen Milligan , Dale Skalla , Kay Lawton
发明人： Stephen Milligan , Dale Skalla , Kay Lawton
IPC分类号： A01H1/00 , A01H5/00 , C07H21/04 , C07K14/415 , C12N5/10 , C12N15/09 , C12N15/63 , C12N15/82 , C12N15/85 , C12N15/87 , C12Q1/68
CPC分类号： C12N15/8227 , C07K14/415
摘要： The present invention is directed to promoters isolated from maize and functional equivalents thereto. The promoters of the present invention have particular utility in driving root-specific expression of heterologous genes that impart increased agronomic, horticultural and/or pesticidal characteristics to a given promoters of the invention and transformed plant tissues containing DNA molecules comprising a promoter of the invention operably linked to a heterologous gene or genes, and seeds thereof.
摘要翻译： 本发明涉及从玉米分离的启动子及其功能等同物。 本发明的启动子在驱动特异性表达的异源基因中具有特别的用途，所述异源基因赋予本发明的给定启动子增加的农学，园艺和/或杀虫特征，以及含有本发明启动子的含有DNA分子的转化植物组织，其可操作地 与异源基因或其基因连接，以及其种子。
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公开(公告)号：US20050132438A1
公开(公告)日：2005-06-16
申请号：US10220665
申请日：2001-03-05
申请人： Helen Wang , John Salmeron , Michael Willits , Kay Lawton
发明人： Helen Wang , John Salmeron , Michael Willits , Kay Lawton
IPC分类号： A01H5/00 , C07K14/415 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/29 , C12N15/82 , C12Q1/68 , A01H1/00 , C07H21/04 , C12N5/04 , C12N9/24
CPC分类号： C12N15/8279 , C07K14/415
摘要： Homologues of the Arabidopsis NIM1 gene, which is involved in the signal transduction cascade leading to systemic acquired resistance (SAR), are isolated from monocotyledonous crops such as Triticum aestivum (wheat) and Oryza sativa (rice). The invention further concerns transformation vectors and processes for expressing the monocotyledonous NIM1 homologues in transgenic plants to increase SAR gene expression and enhance broad spectrum disease resistance
摘要翻译： 拟南芥NIM1基因的同源物，其参与导致系统性获得性抗性（SAR）的信号转导级联，从单子叶作物如小麦（Triticum aestivum）（小麦）和水稻（Rice）中分离。 本发明还涉及用于在转基因植物中表达单子叶NIM1同源物的转化载体和方法，以增加SAR基因表达并增强广谱抗病性
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公开(公告)号：US20100162443A1
公开(公告)日：2010-06-24
申请号：US12689311
申请日：2010-01-19
申请人： Stephen B. MILLIGAN , Dale SKALLA , Kay LAWTON
发明人： Stephen B. MILLIGAN , Dale SKALLA , Kay LAWTON
CPC分类号： C12N15/8227 , C07K14/415
摘要： The present invention is directed to promoters isolated from maize and functional equivalents thereto. The promoters of the present invention have particular utility in driving root-specific expression of heterologous genes that impart increased agronomic, horticultural and/or pesticidal characteristics to a given transgenic plant. The present invention is also drawn to DNA molecules comprising the promoters of the invention and transformed plant tissues containing DNA molecules comprising a promoter of the invention operably linked to a heterologous gene or genes, and seeds thereof.
摘要翻译： 本发明涉及从玉米分离的启动子及其功能等同物。 本发明的启动子在驱动给定转基因植物赋予增加的农艺，园艺和/或杀虫特征的异源基因的根特异性表达方面具有特别的用途。 本发明还涉及包含本发明启动子的DNA分子和含有可操作地连接到异源基因或基因的本发明启动子的DNA分子的转化植物组织及其种子。
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8.发明申请公开(公告)号：US20070298998A1
公开(公告)日：2007-12-27
申请号：US11711518
申请日：2007-02-27
申请人： Lisa Paige , Matthew Mitchell , Anne Evans , Don Harvan , Kay Lawton , Robert Brown , Merit Cudkowicz
发明人： Lisa Paige , Matthew Mitchell , Anne Evans , Don Harvan , Kay Lawton , Robert Brown , Merit Cudkowicz
CPC分类号： G01N33/6896 , G01N2500/10 , G01N2800/28 , G01N2800/2835 , G01N2800/56 , Y10T436/24
摘要： The present invention provides various biomarkers of amyotrophic lateral sclerosis (ALS). The present invention also provides various methods of using the biomarkers, including methods for diagnosis of ALS, methods of determining predisposition to ALS, methods of monitoring progression/regression of ALS, methods of assessing efficacy of compositions for treating ALS, methods of screening compositions for activity in modulating biomarkers of ALS, methods of treating ALS, as well as other methods based on biomarkers of ALS.
摘要翻译： 本发明提供各种肌萎缩性侧索硬化症（ALS）的生物标志物。 本发明还提供了使用生物标志物的各种方法，包括ALS诊断方法，ALS倾向性测定方法，ALS进展/回归监测方法，评估组合物治疗ALS功效的方法，筛选组合物的方法 调节ALS生物标志物的活性，治疗ALS的方法，以及基于ALS生物标志物的其他方法。
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公开(公告)号：US08058420B2
公开(公告)日：2011-11-15
申请号：US12689318
申请日：2010-01-19
申请人： Stephen B. Milligan , Dale Skalla , Kay Lawton
发明人： Stephen B. Milligan , Dale Skalla , Kay Lawton
CPC分类号： C12N15/8227 , C07K14/415
摘要： The present invention is directed to promoters isolated from maize and functional equivalents thereto. The promoters of the present invention have particular utility in driving root-specific expression of heterologous genes that impart increased agronomic, horticultural and/or pesticidal characteristics to a given transgenic plant. The present invention is also drawn to DNA molecules comprising the promoters of the invention and transformed plant tissues containing DNA molecules comprising a promoter of the invention operably linked to a heterologous gene or genes, and seeds thereof.
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公开(公告)号：US07674893B2
公开(公告)日：2010-03-09
申请号：US10490147
申请日：2002-11-04
申请人： Stephen B. Milligan , Dale Skalla , Kay Lawton
发明人： Stephen B. Milligan , Dale Skalla , Kay Lawton
IPC分类号： C12N15/82
CPC分类号： C12N15/8227 , C07K14/415
摘要： The present invention is directed to promoters isolated from maize and functional equivalents thereto. The promoters of the present invention have particular utility in driving root-specific expression of heterologous genes that impart increased agronomic, horticultural and/or pesticidal characteristics to a given promoters of the invention and transformed plant tissues containing DNA molecules comprising a promoter of the invention operably linked to a heterologous gene or genes, and seeds thereof.
摘要翻译： 本发明涉及从玉米分离的启动子及其功能等同物。 本发明的启动子在驱动特异性表达的异源基因中具有特别的用途，所述异源基因赋予本发明的给定启动子增加的农学，园艺和/或杀虫特征，以及含有本发明启动子的含有DNA分子的转化植物组织，其可操作地 与异源基因或其基因连接，以及其种子。
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