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公开(公告)号：US08740799B2
公开(公告)日：2014-06-03
申请号：US12480924
申请日：2009-06-09
申请人： Kazunori Itani
发明人： Kazunori Itani
CPC分类号： A61B8/481 , A61B8/14 , G01S7/52038 , G01S7/52039 , G01S7/52077 , G01S15/104 , G01S15/8918 , G01S15/8954 , G01S15/8959 , G01S15/8961 , G01S15/8963 , G01S15/8993
摘要： A signal generation unit 10 generates, and sends to a transmission circuit 12, a driving signal for forming a transmission pulse. A probe 14 is transmission controlled to transmit ultrasound at a transmission frequency which is set using, as a reference, a resonance frequency of a bubble administered into a living organism, and also at a transmission sound pressure which is set using an expansion ratio of the bubble as a reference. The signal generation unit 10 outputs a transmission pulse having a waveform corresponding to a center frequency of about 1.5 MHz and a transmission sound pressure of about 200 to 300 kPa. With this structure, it is possible to increase a harmonic component obtained from the bubble while suppressing a harmonic component obtained from real tissue, so that extremely high CTR can be obtained.
摘要翻译： 信号生成单元10生成并发送到发送电路12的用于形成发送脉冲的驱动信号。 传感器14被传输控制，以传输频率发送超声波，该传输频率是使用施用于生物体中的气泡的共振频率作为基准设定的，并且还使用以下方式设定的透射声压 泡沫作为参考。 信号生成单元10输出具有对应于约1.5MHz的中心频率和约200〜300kPa的发送声压的波形的发送脉冲。 利用这种结构，可以在抑制从真实组织获得的谐波分量的同时增加从气泡获得的谐波分量，从而可以获得极高的CTR。
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公开(公告)号：US5837198A
公开(公告)日：1998-11-17
申请号：US771799
申请日：1996-12-20
申请人： Kazunori Itani
发明人： Kazunori Itani
CPC分类号： B01L3/50255 , G01N1/312 , Y10T436/113332 , Y10T436/114165 , Y10T436/114998 , Y10T436/25375
摘要： When reagent was discharged in a physiological tissue reagent treatment apparatus, it was troublesome to retain the sample so that it was not discharged together with the reagent. This apparatus offers an improvement on this point, saves work involved in reagent treatment and enables lower costs to be attained. Samples 70 are held in separate sample containers 8. The base of this sample container 8 comprises a mesh 64. Consequently, when the sample container 8 is inserted in a reagent bath 6 in which reagent has collected, reagent flows from this mesh 64 into the container 8. Reagent may flow also from a flow hole 66. The reagent which has flowed into the container 8 acts on the sample 70, and reagent treatment takes place. The reagent in a plurality of the sample containers 8 set in a container holder 10, is then aspirated by a pump 30, or by a nozzle inserted together with the container 8 in the reagent bath, via the mesh 64 of the container. The adjacent reagent baths 6 are mutually independent, and reagent is injected only into the reagent bath 6 to be used for the reaction. Only contaminated sample containers 8 are discarded as necessary.
摘要翻译： 当在生理组织试剂处理装置中排出试剂时，保持样品使其不与试剂一起排出是麻烦的。 该设备在这一点上有所改进，可以节省试剂处理中的工作量，从而降低成本。 样品70保持在单独的样品容器8中。该样品容器8的底部包括网孔64.因此，当将样品容器8插入其中已经收集试剂的试剂槽6中时，试剂从该筛网64流入 容器8.试剂也可以从流动孔66流出。已经流入容器8的试剂作用在样品70上，并进行试剂处理。 设置在容器保持器10中的多个样本容器8中的试剂经由泵30或通过与容器8一起插入试剂槽中的喷嘴经由容器的筛网64吸出。 相邻的试剂浴6是相互独立的，并且试剂仅被注入用于反应的试剂槽6中。 必要时只有被污染的样品容器8被丢弃。
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公开(公告)号：US20100036255A1
公开(公告)日：2010-02-11
申请号：US12480924
申请日：2009-06-09
申请人： Kazunori Itani
发明人： Kazunori Itani
IPC分类号： A61B8/14
CPC分类号： A61B8/481 , A61B8/14 , G01S7/52038 , G01S7/52039 , G01S7/52077 , G01S15/104 , G01S15/8918 , G01S15/8954 , G01S15/8959 , G01S15/8961 , G01S15/8963 , G01S15/8993
摘要： A signal generation unit 10 generates, and sends to a transmission circuit 12, a driving signal for forming a transmission pulse. A probe 14 is transmission controlled to transmit ultrasound at a transmission frequency which is set using, as a reference, a resonance frequency of a bubble administered into a living organism, and also at a transmission sound pressure which is set using an expansion ratio of the bubble as a reference. The signal generation unit 10 outputs a transmission pulse having a waveform corresponding to a center frequency of about 1.5 MHz and a transmission sound pressure of about 200 to 300 kPa. With this structure, it is possible to increase a harmonic component obtained from the bubble while suppressing a harmonic component obtained from real tissue, so that extremely high CTR can be obtained.
摘要翻译： 信号生成单元10生成并发送到发送电路12的用于形成发送脉冲的驱动信号。 传感器14被传输控制，以传输频率发送超声波，该传输频率是使用施用于生物体中的气泡的共振频率作为基准设定的，并且还使用以下方式设定的透射声压 泡沫作为参考。 信号生成单元10输出具有对应于约1.5MHz的中心频率和约200〜300kPa的发送声压的波形的发送脉冲。 利用这种结构，可以在抑制从真实组织获得的谐波分量的同时增加从气泡获得的谐波分量，从而可以获得极高的CTR。
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公开(公告)号：US5776414A
公开(公告)日：1998-07-07
申请号：US788547
申请日：1997-01-24
申请人： Kazunori Itani , Kouhei Kihara , Shogo Iijima
发明人： Kazunori Itani , Kouhei Kihara , Shogo Iijima
CPC分类号： G01N1/312 , Y10T436/11 , Y10T436/112499 , Y10T436/114165 , Y10T436/115831
摘要： A physiological tissue sample on a glass slide is treated by a reagent. A reagent bath is formed so that its horizontal depth becomes progressively larger from the lower part to the upper part. In a first treatment mode, a small amount of reagent is introduced in the reagent bath, and a sample plate is introduced into the bath up to a first treatment position. In a second treatment mode, a large amount of reagent is introduced in the reagent bath, and a sample plate is introduced into the bath up to a second treatment position.
摘要翻译： 玻璃载片上的生理组织样品用试剂处理。 形成试剂槽，使其水平深度从下部到上部逐渐变大。 在第一处理模式中，在试剂槽中引入少量试剂，将试样板引入到第一处理位置。 在第二处理模式中，在试剂槽中引入大量试剂，将试样板引入到第二处理位置。
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