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    Composition for the treatment of symptoms and conditions associated with aging
    1.
    发明授权
    Composition for the treatment of symptoms and conditions associated with aging 失效

    公开(公告)号：US07011856B2

    公开(公告)日：2006-03-14

    申请号：US10045972

    申请日：2002-02-28

    申请人： Ken-ichi Kosuna

    发明人： Ken-ichi Kosuna

    IPC分类号： A61K35/78

    CPC分类号： A61K36/70 ,  A61K2300/00

    摘要： A composition including an extract of buckwheat seed and a fractionation product of the extract of buckwheat seed useful for the prevention and therapy of aging is disclosed. The composition prevents, treats and improves aging phenomena such as the symptoms of Alzheimer's syndrome and pathological lesions of the brain. Further, the composition activates and improves the function of a brain including the ability to learn, memorize, and think, as well as providing other physiological benefits.

    Substance derived from basidiomycetes culture, method for producing it and its use
    2.
    发明授权
    Substance derived from basidiomycetes culture, method for producing it and its use 有权
    源自担子菌培养物的物质，其生产方法及其用途

    公开(公告)号：US07883708B2

    公开(公告)日：2011-02-08

    申请号：US12149002

    申请日：2008-04-24

    申请人： Ken-ichi Kosuna ,  Lan Yuan ,  Takehito Miura ,  Buxiang Sun

    发明人： Ken-ichi Kosuna ,  Lan Yuan ,  Takehito Miura ,  Buxiang Sun

    IPC分类号： A61K36/07 ,  A61K36/074 ,  A61K65/00 ,  A61K38/47

    CPC分类号： A61K36/074 ,  A23K10/12 ,  A23K20/121 ,  A23L33/10 ,  A23L33/105 ,  A23V2002/00 ,  A61K31/352 ,  A61K36/07 ,  C12P17/06 ,  A23V2250/21172

    摘要： A novel substance that has the physiological activity of the aglycone of isoflavones and the physiological activity of the culture of the basidiomycetes with the physiological activities being synergistically enhanced, obtained by cultivating a basidiomycetes having a β-glucosidase activity in a medium containing an isoflavone, a method for producing it, and food, feedstuff and medicine containing it.The substance of the invention is improved in the physiological effect of the aglycone of isoflavones and the physiological effect of the culture of the basidiomycetes, and is not only useful as an anti-tumor agent but also is useful for therapy and/or prevention of osteoporosis and also as an immune enhancement agent.

    摘要翻译： 通过在含有异黄酮的培养基中培养具有葡糖苷酶活性的担子菌，得到协同增强的具有异黄酮糖苷配基的生理活性和担子菌培养物的生理活性的新物质， 其制造方法，以及含有其的食品，饲料和药物。 本发明的物质改善了异黄酮苷元的生理效应和担子菌培养的生理作用，不仅可用作抗肿瘤剂，而且可用于治疗和/或预防骨质疏松症 并且还作为免疫增强剂。

    Novel substance derived from basidiomycetes culture, method for producing it and its use
    4.
    发明申请
    Novel substance derived from basidiomycetes culture, method for producing it and its use 有权
    从担子菌培养物得到的新物质，其生产方法及其用途

    公开(公告)号：US20090004247A1

    公开(公告)日：2009-01-01

    申请号：US12149002

    申请日：2008-04-24

    申请人： Ken-ichi Kosuna ,  Lan Yuan ,  Takehito Miura ,  Buxiang Sun

    发明人： Ken-ichi Kosuna ,  Lan Yuan ,  Takehito Miura ,  Buxiang Sun

    IPC分类号： A61K36/07 ,  C12N1/14 ,  A61P35/00

    CPC分类号： A61K36/074 ,  A23K10/12 ,  A23K20/121 ,  A23L33/10 ,  A23L33/105 ,  A23V2002/00 ,  A61K31/352 ,  A61K36/07 ,  C12P17/06 ,  A23V2250/21172

    摘要： A novel substance that has the physiological activity of the aglycone of isoflavones and the physiological activity of the culture of the basidiomycetes with the physiological activities being synergistically enhanced, obtained by cultivating a basidiomycetes having a β-glucosidase activity in a medium containing an isoflavone, a method for producing it, and food, feedstuff and medicine containing it.The substance of the invention is improved in the physiological effect of the aglycone of isoflavones and the physiological effect of the culture of the basidiomycetes, and is not only useful as an anti-tumor agent but also is useful for therapy and/or prevention of osteoporosis and also as an immune enhancement agent.

    摘要翻译： 通过在含有异黄酮的培养基中培养具有β-葡糖苷酶活性的担子菌纲获得的，具有协同增强的生物活性的具有异黄酮苷元的生理活性和担子菌培养物的生理活性的新物质， 生产方法，食品，饲料和包含它的药物。 本发明的物质改善了异黄酮苷元的生理效应和担子菌培养的生理作用，不仅可用作抗肿瘤剂，而且可用于治疗和/或预防骨质疏松症 并且还作为免疫增强剂。