公开(公告)号：US07793085B2

公开(公告)日：2010-09-07

申请号：US11024843

申请日：2004-12-30

Applicant: Kenji Furuya

Inventor： Kenji Furuya

IPC: G06F9/30

CPC classification number: G06F9/3804

Abstract: A memory control circuit for providing a small-circuit-size memory control circuit capable of reducing a branch penalty during the execution of a branch instruction in a CPU. A branch-destination buffer caches a branch-destination instruction and a branch-destination-instruction address determined by a branch instruction executed by the CPU. When the CPU executes a branch instruction thereafter, if the branch-destination-instruction address output from the CPU matches an instruction address in the branch-destination buffer, the corresponding branch-destination instruction stored in the branch-destination buffer is sent to the CPU. When a branch instruction is executed, an address comparison circuit compares the branch-destination-instruction address with the branch-source-instruction address. A buffer-update control circuit updates data of the branch-destination buffer by the branch-destination instruction only when it is determined according to the result of comparison performed by the address comparison circuit that the instruction address has been changed in the negative direction by the instruction branch.

Abstract translation: 一种存储器控制电路，用于提供在CPU中执行分支指令期间能够减少分支损失的小电路尺寸的存储器控​​制电路。 分支目的地缓冲器缓存由CPU执行的分支指令确定的分支目的地指令和分支目的地指令地址。 当CPU执行分支指令之后，如果从CPU输出的分支目的地指令地址与分支目的地缓冲器中的指令地址相匹配，则将分支目的地缓冲器中存储的相应分支目的地指令发送到CPU 。 当执行分支指令时，地址比较电路将分支目的地指令地址与分支源指令地址进行比较。 只有当根据地址比较电路执行的比较结果确定指令地址已经沿负方向改变时，缓冲器更新控制电路才通过分支目的地指令更新分支目的地缓冲器的数据 指令科

公开(公告)号：US20090311216A1

公开(公告)日：2009-12-17

申请号：US12375958

申请日：2007-07-24

Applicant: Deborah Johnson-Jackson ,  Kenji Furuya ,  Isabel Zaror ,  Douglas Larson

Inventor： Deborah Johnson-Jackson ,  Kenji Furuya ,  Isabel Zaror ,  Douglas Larson

IPC: A61K38/21 ,  C07K14/565 ,  C12P21/02 ,  C12Q1/37 ,  C12N15/22 ,  C12N1/21 ,  C12N5/10 ,  A61P37/00

CPC classification number: C07K14/565

Abstract: Human interferon-β protein analogs in which the asparagine at position 25, numbered in accordance with native human interferon-β, is recombinantly replaced with an aspartate residue exhibit a biological activity of human interferon-β (e.g. IFN-β 1b) at an increased level relative to IFN-β 1b. These analogs are obtained by introducing a gene coding for Asp25 IFN-β into a cell and expressing the recombinant protein. The resulting IFN-β protein analog is suitable for large scale manufacturing for incorporation in HA-containing or HA-free therapeutics for treatment of diseases including multiple sclerosis. A reduced Lys endoproteinase-C peptide map technique that produces a fingerprint profile for proteins using an enzymatic digest followed by RP-HPLC is also useful in quality control as an ID test for the IFN-β protein analog products.

Abstract translation: 人类干扰素-β蛋白类似物，其中根据天然人类干扰素-β编号的第25位的天冬酰胺用天冬氨酸残基重组取代，表现出增加的人干扰素-β（例如IFN-β1b）的生物学活性 水平相对于IFN-β1b。 这些类似物通过将编码Asp25 IFN-β的基因导入细胞并表达重组蛋白而获得。 所得的IFN-β蛋白类似物适用于大规模制造，用于掺入含HA或不含HA的治疗剂中用于治疗包括多发性硬化的疾病。 使用酶消化产生RP-HPLC产生蛋白质指纹图谱的降低的Lys内蛋白酶-C肽图技术也可作为IFN-β蛋白质类似物产品的ID测试的质量控制。

公开(公告)号：US20090263355A1

公开(公告)日：2009-10-22

申请号：US12410540

申请日：2009-03-25

Applicant: KENJI FURUYA ,  DEBORAH JOHNSON-JACKSON ,  DIANA TIERRA RUSCIO

Inventor： KENJI FURUYA ,  DEBORAH JOHNSON-JACKSON ,  DIANA TIERRA RUSCIO

IPC: A61K38/21 ,  C07K14/52 ,  C12Q1/00

CPC classification number: C07K14/565 ,  A61K38/00

Abstract: Interferon-β protein analogs in which the asparagine at position 25, numbered in accordance with native interferon-β, is deamidated exhibit a biological activity of native human interferon-β at an increased level and do not require HA for protein stabilization. The deamidated product is suitable for large scale manufacturing for incorporation in HA-containing or HA-free therapeutics for treatment of diseases including multiple sclerosis. An endoproteinase-C peptide map technique that produces a fingerprint profile for proteins using an enzymatic digest followed by RP-HPLC is also useful in quality control as an ID and/or quantitative test for the deamidated products.

Abstract translation: 干扰素-β蛋白类似物，其中根据天然干扰素-β编号的位置25的天冬酰胺被脱酰氨基显示出增加水平的天然人干扰素-β的生物活性，并且不需要HA用于蛋白质稳定。 脱酰胺产品适用于大规模生产，用于纳入含HA或不含HA的治疗剂，用于治疗包括多发性硬化症在内的疾病。 使用酶消化产生RP-HPLC产生蛋白质指纹图谱的内蛋白酶C肽图技术也可用于作为脱酰胺产物的ID和/或定量测试的质量控制。

公开(公告)号：US07595040B2

公开(公告)日：2009-09-29

申请号：US11271516

申请日：2005-11-10

Applicant: Kenji Furuya ,  Deborah Johnson-Jackson ,  Diana Tierra Ruscio

Inventor： Kenji Furuya ,  Deborah Johnson-Jackson ,  Diana Tierra Ruscio

IPC: A61K38/21 ,  C07K14/565

CPC classification number: C07K14/565 ,  A61K38/00

Abstract: Interferon-β protein analogs in which the asparagine at position 25, numbered in accordance with native interferon-β, is deamidated exhibit a biological activity of native human interferon-β at an increased level and do not require HA for protein stabilization. The deamidated product is suitable for large scale manufacturing for incorporation in HA-containing or HA-free therapeutics for treatment of diseases including multiple sclerosis. An endoproteinase-C peptide map technique that produces a fingerprint profile for proteins using an enzymatic digest followed by RP-HPLC is also useful in quality control as an ID and/or quantitative test for the deamidated products.

Abstract translation: 干扰素-β蛋白类似物，其中根据天然干扰素-β编号的位置25的天冬酰胺被脱酰氨基显示出增加水平的天然人干扰素-β的生物活性，并且不需要HA用于蛋白质稳定。 脱酰胺产品适用于大规模生产，用于纳入含HA或不含HA的治疗剂，用于治疗包括多发性硬化症在内的疾病。 使用酶消化产生RP-HPLC产生蛋白质指纹图谱的内蛋白酶C肽图技术也可用于作为脱酰胺产物的ID和/或定量测试的质量控制。

公开(公告)号：US07438837B2

公开(公告)日：2008-10-21

申请号：US10549290

申请日：2004-03-19

Applicant: Masaharu Hatano ,  Mitsugu Yamanaka ,  Makoto Uchiyama ,  Kenji Furuya ,  Yoshio Akimune ,  Masaya Okamoto

Inventor： Masaharu Hatano ,  Mitsugu Yamanaka ,  Makoto Uchiyama ,  Kenji Furuya ,  Yoshio Akimune ,  Masaya Okamoto

IPC: C04B35/48 ,  C04B35/645 ,  H01B1/08 ,  H01M8/02 ,  B28B1/00

CPC classification number: C04B35/486 ,  C04B35/64 ,  C04B35/645 ,  C04B2235/3224 ,  C04B2235/449 ,  C04B2235/5445 ,  C04B2235/656 ,  C04B2235/6562 ,  C04B2235/6567 ,  C04B2235/6581 ,  C04B2235/661 ,  C04B2235/666 ,  C04B2235/762 ,  C04B2235/77 ,  C04B2235/786 ,  C04B2235/96 ,  H01M8/1253 ,  Y02E60/525 ,  Y02P70/56

Abstract: A method of producing a solid electrolyte (3, 13) is disclosed wherein solid electrolyte material is prepared having a composition expressed by a formula: (1-x) ZrO2 {xSc2O3 (where x is a number equal to or greater than 0.05 and equal to or less than 0.15), and a spark plasma method is carried out to sinter solid electrolyte material, resulting in a solid electrolyte. Such spark plasma method is executed by applying first compression load, equal to or less that 40 MPa, to solid electrolyte material, to sinter the solid electrolyte material to obtain sintered material, which is then cooled by applying second compression load, less than first compression load, to the sintered material, resulting in a solid electrolyte.

Abstract translation: 公开了一种制备固体电解质（3,13）的方法，其中制备具有由下式表示的组成的固体电解质材料：（1-x）ZrO 2 {xSc2 / （其中x是等于或大于0.05且等于或小于0.15的数），并且进行火花等离子体法以烧结固体电解质材料，得到固体 电解液 通过对固体电解质材料施加等于或小于40MPa的第一压缩载荷来烧结固体电解质材料以获得烧结材料，然后通过施加小于第一压缩的第二压缩载荷进行冷却来执行这种火花等离子体法 加载到烧结材料中，得到固体电解质。

公开(公告)号：US07205063B2

公开(公告)日：2007-04-17

申请号：US10464457

申请日：2003-06-19

Applicant: Kenji Furuya ,  Masaharu Hatano ,  Kazunori Fujii

Inventor： Kenji Furuya ,  Masaharu Hatano ,  Kazunori Fujii

IPC: C04B35/50 ,  H01M4/86 ,  C01F17/00

CPC classification number: C04B35/01 ,  C04B35/6262 ,  C04B2235/3206 ,  C04B2235/3208 ,  C04B2235/3213 ,  C04B2235/3215 ,  C04B2235/3217 ,  C04B2235/3227 ,  C04B2235/3284 ,  C04B2235/3286 ,  C04B2235/5445 ,  C04B2235/6567 ,  C04B2235/768 ,  C04B2235/78 ,  C04B2235/785 ,  C04B2235/786 ,  C04B2235/80 ,  C04B2235/96 ,  H01M8/1246 ,  H01M2008/1293 ,  Y02E60/525 ,  Y02P70/56

Abstract: A lanthanum gallate-based sintered body comprises a base material formed of lanthanum gallate-based oxide, and grains having a K2NiF4 structure and/or grains having a layered perovskite structure are dispersed into the base material. Consequently, the lanthanum gallate-based sintered body has a high mechanical strength and is excellent in thermal resistance. Further, a SOFC having excellent properties can be obtained by using the lanthanum gallate-based sintered body as the solid electrolyte.

Abstract translation: 无镓酸镧系烧结体包括由没有没食子酸镧的氧化物形成的基体材料和具有K 2 NiFe 4 O 4结构的晶粒和/或具有层状钙钛矿的晶粒 结构分散在基材中。 因此，没食子酸镓酸盐系烧结体的机械强度高，耐热性优异。 此外，通过使用无铼酸镧系烧结体作为固体电解质可以获得具有优异性能的SOFC。

公开(公告)号：US07136956B2

公开(公告)日：2006-11-14

申请号：US10090822

申请日：2002-03-06

Applicant: Kenji Furuya ,  Hirokazu Kanma

Inventor： Kenji Furuya ,  Hirokazu Kanma

IPC: G06F13/00

CPC classification number: G06F13/4217 ,  Y02D10/14 ,  Y02D10/151

Abstract: A semiconductor device includes: a plurality of function blocks; a plurality of buses, each of which is respectively connected to one of the plurality of function blocks; a plurality of control signal lines, each of which is respectively connected to one of the plurality of function blocks; a main bus; a bus control unit connected to the main bus; a bus division control unit located between the plurality of buses and the main bus, for connecting one of the plurality of buses to the main bus and transmitting a control signal to a corresponding one of the plurality of control signal lines in accordance with a decoded result of information supplied from the bus control unit via the main bus, thereby controlling a corresponding one of the plurality of function blocks.

公开(公告)号：US07073045B2

公开(公告)日：2006-07-04

申请号：US10797104

申请日：2004-03-11

Applicant: Akio Hara ,  Masaaki Tani ,  Kenji Furuya

Inventor： Akio Hara ,  Masaaki Tani ,  Kenji Furuya

IPC: G06F9/32

CPC classification number: G06F9/3814 ,  G06F9/3804 ,  G06F12/0862 ,  G06F2212/6022

Abstract: Each prefetch buffer has a tag register for storing a branch address and a data register for storing instruction data. Each of the prefetch buffers is assigned to either a first prefetch buffer rewritable during a normal operation period and a second prefetch buffer to be disabled for rewrite during the normal operation period. The second prefetch buffer can thus be prevented from being rewritten even if a central processor outputs branch addresses frequently. This realizes an improvement in the instruction fetch efficiency of the central processor and an improvement in the entire system performance. The fetch efficiency can be improved particularly in such systems that branch addresses occur frequently and some of them occur repeatedly.

Abstract translation: 每个预取缓冲器具有用于存储分支地址的标签寄存器和用于存储指令数据的数据寄存器。 每个预取缓冲器被分配给在正常操作期间可重写的第一预取缓冲器和在正常操作期间被禁止重写的第二预取缓冲器。 因此即使中央处理器频繁地输出分支地址，也可以防止第二预取缓冲器被重写。 这实现了中央处理器的指令获取效率的提高和整个系统性能的提高。 特别是在分支地址频繁发生并且其中一些重复发生的系统中，提取效率可以得到改善。

公开(公告)号：US06774526B2

公开(公告)日：2004-08-10

申请号：US10151838

申请日：2002-05-21

Applicant: Kenji Furuya ,  Makoto Kimura

Inventor： Kenji Furuya ,  Makoto Kimura

IPC: H02K100

CPC classification number: H02K13/04 ,  H01R13/03 ,  H01R39/32 ,  H01R43/0221 ,  Y10T29/49011

Abstract: A rotor for a small-sized motor has a plurality of rotor magnetic poles and a commutator on a rotor shaft, and both ends of a wire of each winding of the rotor magnetic poles are tied up with and connected by spot welding to a U-shaped hook-type commutator leg connected to the corresponding commutator piece end of the commutator, respectively. The commutator leg has a copper-based base material, and is composed by attaching a thin layer of a clad material with a melting point lower than that of the above described base material and a high electric resistance thereon at the surface part to be inside when bent to the U-shaped hook type. Thus, in the connection between the commutator leg and the copper wire material of the small-sized motor, the reduction of defectives of breaking of the wire because of heat shock at the time of welding is achieved, and in the meantime, the stabilization of welding is achieved, so that the reliability of the connection can be increased.

公开(公告)号：US06731041B2

公开(公告)日：2004-05-04

申请号：US10075931

申请日：2002-02-14

Applicant: Kenji Furuya ,  Makoto Kimura

Inventor： Kenji Furuya ,  Makoto Kimura

IPC: H02K1300

CPC classification number: H01R39/54 ,  H02K13/04 ,  H02K13/105 ,  Y10T29/49009 ,  Y10T29/49011 ,  Y10T29/49012 ,  Y10T29/49071 ,  Y10T29/49073

Abstract: Each of the rotor magnetic poles is composed of a winding around a laminated core and each of both ends of each wound wire is connected to a commutator leg part coupled with a tip of a corresponding commutator segment of the commutator unit. Each of the commutator leg parts includes a base portion extending outward in a direction substantially normal to the radial direction from the tip of the corresponding commutator segment tip and coupled to the commutator segment top and a tip portion narrowed stepwise to let the ends of a wound wire be connected. A disk-shaped varistor having a hole at the center is mounted over the base portion of the commutator leg part, and each electrode of the varistor is soldered onto the corresponding base portion. Further, the commutator leg parts are punched and cut out of a reel-wound flat parent metal sheet and fixed to the commutator segment tips.

Abstract translation: 每个转子磁极由围绕层叠铁心的绕组构成，并且每条缠绕线的每一端连接到与换向器单元的相应换向器段的尖端耦合的换向器支脚部分。 每个换向器腿部包括基本部分，其从大致垂直于径向方向的方向向外延伸，该基部从相应的换向器片段末端的尖端延伸并且连接到换向器片段顶部，并且尖端部分逐渐变窄以使伤口的端部 电线连接。 在整流子脚部的基部上安装有在中央具有孔的盘状变阻器，并且将变阻器的每个电极焊接到相应的基部上。 此外，换向器腿部被卷绕并从卷绕的扁平母体金属片上切出并固定到换向器片末端。