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公开(公告)号:US20080019999A1
公开(公告)日:2008-01-24
申请号:US11800860
申请日:2007-05-08
申请人: George Vratsanos , Francisco Leon , Lee Tay , Kenneth Bahrt
发明人: George Vratsanos , Francisco Leon , Lee Tay , Kenneth Bahrt
IPC分类号: A61K39/145 , A61K39/02 , A61P31/16
CPC分类号: C07K14/70521 , A61K39/00 , A61K39/08 , A61K39/092 , A61K39/12 , A61K39/145 , A61K2039/545 , A61K2039/55516 , A61K2039/57 , A61K2039/70 , C07K2319/30 , C07K2319/32 , C12N2760/16134 , C12N2760/16234 , A61K2300/00
摘要: The present invention relates to methods of vaccinating subjects receiving immune modulating therapy, such as soluble CTLA4 molecules, for treatment of immune system diseases mediated by T-cell interactions with B7-positive cells including, but not limited to, autoimmune diseases, immunoproliferative diseases, and immune disorders associated with graft transplantation.
摘要翻译: 本发明涉及接种免疫调节治疗的受试者(例如可溶性CTLA4分子)的疫苗接种方法,用于治疗由与B7阳性细胞的T细胞相互作用介导的免疫系统疾病,包括但不限于自身免疫性疾病,免疫增殖性疾病, 和与移植物移植相关的免疫疾病。