公开(公告)号：US08437863B2

公开(公告)日：2013-05-07

申请号：US13140729

申请日：2008-12-19

申请人： Åke Sivard ,  Gustav Pellijeff ,  Hans Strandberg ,  Leda Henriquez ,  Åsa Broomé ,  Kenneth Dahlberg

发明人： Åke Sivard ,  Gustav Pellijeff ,  Hans Strandberg ,  Leda Henriquez ,  Åsa Broomé ,  Kenneth Dahlberg

IPC分类号： A61N1/05

CPC分类号： A61N1/05 ,  A61N1/086 ,  A61N1/3688 ,  A61N1/3718

摘要： An implantable electrode lead for tissue stimulation adapted to be attached to an implantable tissue stimulator provided with a pulse generator, has at least two stimulation electrodes to apply stimulation pulses to said tissue and arranged close to the distal end of the electrode lead, and at least two electrical conductors to connect said electrodes to said pulse generator. The electrode lead further has a switching unit arranged close to the distal end of the electrode lead and adapted to switch the electrode lead between a local pacing mode and a normal pacing mode, the switching unit being controlled by a mode control signal. Further, a pacing module is arranged close to the distal end of the electrode lead and in relation to the switching unit and being connectable to said at least two stimulation electrodes, the pacing module includes a pulse generating unit to generate stimulating pulses to be applied to the tissue by the stimulation electrodes. When the electrode lead is in the local pacing mode the electrical conductors are disconnected from said stimulation electrodes which instead are connected to the pacing module, and when the electrode lead is in the normal pacing mode the electrical conductors are connected to the stimulation electrodes.

摘要翻译： 一种用于组织刺激的可植入电极引线，其适用于连接到具有脉冲发生器的可植入组织刺激器，具有至少两个刺激电极，以将刺激脉冲施加到所述组织并且靠近电极引线的远端布置，并且至少 两个电导体将所述电极连接到所述脉冲发生器。 电极引线还具有靠近电极引线的远端布置的开关单元，并且适于在局部起搏模式和正常起搏模式之间切换电极引线，开关单元由模式控制信号控制。 此外，起搏模块靠近电极引线的远端设置，并且相对于开关单元设置并且可连接到所述至少两个刺激电极，所述起搏模块包括脉冲产生单元，用于产生刺激脉冲以施加到 由刺激电极组织。 当电极引线处于局部起搏模式时，电导体与所述刺激电极断开，代替地连接到起搏模块，并且当电极引线处于正常起搏模式时，电导体连接到刺激电极。

公开(公告)号：US20110251654A1

公开(公告)日：2011-10-13

申请号：US13140729

申请日：2008-12-19

申请人： Åke Sivard ,  Gustav Pellijeff ,  Hans Strandberg ,  Leda Henriquez ,  Åsa Broomé ,  Kenneth Dahlberg

发明人： Åke Sivard ,  Gustav Pellijeff ,  Hans Strandberg ,  Leda Henriquez ,  Åsa Broomé ,  Kenneth Dahlberg

IPC分类号： A61N1/365 ,  A61N1/362

CPC分类号： A61N1/05 ,  A61N1/086 ,  A61N1/3688 ,  A61N1/3718

摘要： An implantable electrode lead for tissue stimulation adapted to be attached to an implantable tissue stimulator provided with a pulse generator, has at least two stimulation electrodes to apply stimulation pulses to said tissue and arranged close to the distal end of the electrode lead, and at least two electrical conductors to connect said electrodes to said pulse generator. The electrode lead further has a switching unit arranged close to the distal end of the electrode lead and adapted to switch the electrode lead between a local pacing mode and a normal pacing mode, the switching unit being controlled by a mode control signal. Further, a pacing module is arranged close to the distal end of the electrode lead and in relation to the switching unit and being connectable to said at least two stimulation electrodes, the pacing module includes a pulse generating unit to generate stimulating pulses to be applied to the tissue by the stimulation electrodes. When the electrode lead is in the local pacing mode the electrical conductors are disconnected from said stimulation electrodes which instead are connected to the pacing module, and when the electrode lead is in the normal pacing mode the electrical conductors are connected to the stimulation electrodes.

摘要翻译： 一种用于组织刺激的可植入电极引线，其适用于连接到具有脉冲发生器的可植入组织刺激器，具有至少两个刺激电极，以将刺激脉冲施加到所述组织并且靠近电极引线的远端布置，并且至少 两个电导体将所述电极连接到所述脉冲发生器。 电极引线还具有靠近电极引线的远端布置的开关单元，并且适于在局部起搏模式和正常起搏模式之间切换电极引线，开关单元由模式控制信号控制。 此外，起搏模块靠近电极引线的远端设置，并且相对于开关单元设置并且可连接到所述至少两个刺激电极，所述起搏模块包括脉冲产生单元，用于产生刺激脉冲以施加到 由刺激电极组织。 当电极引线处于局部起搏模式时，电导体与所述刺激电极断开，代替地连接到起搏模块，并且当电极引线处于正常起搏模式时，电导体连接到刺激电极。

公开(公告)号：US20090171425A1

公开(公告)日：2009-07-02

申请号：US12280500

申请日：2006-03-02

申请人： Kenneth Dahlberg

发明人： Kenneth Dahlberg

IPC分类号： A61N1/05

CPC分类号： A61N1/05 ,  A61N1/056 ,  Y10T29/49117

摘要： A medically implantable lead configured for insertion into a human or animal body to be attached in the body with its distal end to tissue inside the body, as a rotatable helix at a distal end thereof that can be screwed into the tissue. The helix serves as an attachment of the lead to the tissue as well as a conductor for conducting electrical signals to the tissue through electrically conducting surfaces on the helix. The surfaces of the helix are partly insulated so as to restrict the conducting of signals between the helix and the tissue to desirable regions. The surfaces of the helix facing inwardly, toward an inner bore of the helix, are electrically insulated. In a method for manufacturing such a lead, the wire forming the helix has protrusions in desired areas and the wire including the protrusions is coated with an electrically insulating layer. The protrusions are uncovered from the insulating layer in desired regions.

摘要翻译： 一种医学上可植入的引线，其构造成用于插入人体或动物体中，其主体的远端位于身体内部，作为其远端处的可旋转螺旋，其可被螺纹连接到组织中。 螺旋作为引线附着到组织以及用于通过螺旋上的导电表面向组织传导电信号的导体。 螺旋的表面被部分地绝缘，以便将螺旋和组织之间的信号传导限制到所需区域。 螺旋面向内，朝向螺旋的内孔的表面是电绝缘的。 在制造这种引线的方法中，形成螺旋线的线具有所需区域中的突起，并且包括突起的线被涂覆有电绝缘层。 突出物在期望的区域中从绝缘层未被覆盖。

公开(公告)号：US20080228270A1

公开(公告)日：2008-09-18

申请号：US12065106

申请日：2005-09-28

申请人： Kenneth Dahlberg

发明人： Kenneth Dahlberg

IPC分类号： A61F2/02 ,  A61N1/00

CPC分类号： A61N1/3718 ,  A61N1/3754

摘要： An implantable medical device has a hermetically sealed housing with at least one feedthrough therein for a conductive path between an RF antenna carried by the housing, and an RF telemetry circuit contained in the housing. The feedthrough has a feedthrough housing with a capacitor element therein having first and second capacitor plate configurations, with a first of the capacitor plate configurations being connected to the RF antenna and a second of the capacitor plate configurations being connected to the RF telemetry circuit. The feedthrough functions both as a hermetic seal and as a galvanic isolation for voltage protection of the components of the RF telemetry circuit, and other circuitry in the sealed housing connected thereto.

摘要翻译： 可植入医疗装置具有气密密封的壳体，其中至少有一个馈通用于由壳体承载的RF天线与容纳在壳体中的RF遥测电路之间的导电路径。 馈通具有其中具有第一和第二电容器板配置的电容器元件的馈通外壳，电容器板配置中的第一个连接到RF天线，并且电容器板配置中的第二个连接到RF遥测电路。 馈通功能既作为气密密封又用作电流隔离，用于RF遥测电路的部件的电压保护以及与其连接的密封壳体中的其它电路。

公开(公告)号：US20060235325A1

公开(公告)日：2006-10-19

申请号：US10524196

申请日：2003-06-23

申请人： Nils Holmstrom ,  Martin Obel ,  Anna Norlin ,  Kenneth Dahlberg ,  Anders Bjorling ,  Sven Kalling ,  Karin Ljungstrom ,  Kjell Noren

发明人： Nils Holmstrom ,  Martin Obel ,  Anna Norlin ,  Kenneth Dahlberg ,  Anders Bjorling ,  Sven Kalling ,  Karin Ljungstrom ,  Kjell Noren

IPC分类号： A61B5/05 ,  A61B5/02

CPC分类号： A61B5/0538 ,  A61B5/053 ,  A61N1/3627

摘要： A congestive heart failure monitor has an impedance measuring unit that measures the impedance between at least two electrodes implanted in a patient, to use a detected change of the measured impedance as an indication of a change in the left atrium volume. Any analyzing unit analyzes the measured impedance and detects insipient congestive heart failure dependent on a quotient of a maximum value of the measured impedance and a minimum value of the measured impedance during a cardiac cycle.

摘要翻译： 充血性心力衰竭监测器具有阻抗测量单元，其测量植入患者中的至少两个电极之间的阻抗，以使用检测到的测量阻抗的变化作为左心房体积变化的指示。 任何分析单元分析所测量的阻抗，并根据所测量的阻抗的最大值和心动周期内所测量的阻抗的最小值来检测不利的充血性心力衰竭。

公开(公告)号：US08099177B2

公开(公告)日：2012-01-17

申请号：US12280500

申请日：2006-03-02

申请人： Kenneth Dahlberg

发明人： Kenneth Dahlberg

IPC分类号： A61N1/05

CPC分类号： A61N1/05 ,  A61N1/056 ,  Y10T29/49117

摘要： A medically implantable lead configured for insertion into a human or animal body to be attached in the body with its distal end to tissue inside the body, as a rotatable helix at a distal end thereof that can be screwed into the tissue. The helix serves as an attachment of the lead to the tissue as well as a conductor for conducting electrical signals to the tissue through electrically conducting surfaces on the helix. The surfaces of the helix are partly insulated so as to restrict the conducting of signals between the helix and the tissue to desirable regions. The surfaces of the helix facing inwardly, toward an inner bore of the helix, are electrically insulated. In a method for manufacturing such a lead, the wire forming the helix has protrusions in desired areas and the wire including the protrusions is coated with an electrically insulating layer. The protrusions are uncovered from the insulating layer in desired regions.

摘要翻译： 一种医学上可植入的引线，其构造成用于插入人体或动物体中，其主体的远端位于身体内部，作为其远端处的可旋转螺旋，其可被螺纹连接到组织中。 螺旋作为引线附着到组织以及用于通过螺旋上的导电表面向组织传导电信号的导体。 螺旋的表面被部分地绝缘，以便将螺旋和组织之间的信号传导限制到所需区域。 螺旋面向内，朝向螺旋的内孔的表面是电绝缘的。 在制造这种引线的方法中，形成螺旋线的线具有所需区域中的突起，并且包括突起的线被涂覆有电绝缘层。 突出物在期望的区域中从绝缘层未被覆盖。

公开(公告)号：US20110245646A1

公开(公告)日：2011-10-06

申请号：US13132125

申请日：2008-12-02

申请人： Hans Strandberg ,  Åke Sivard ,  Åsa Broomé ,  Kenneth Dahlberg ,  Gustav Pellijeff ,  Leda Henriquez

发明人： Hans Strandberg ,  Åke Sivard ,  Åsa Broomé ,  Kenneth Dahlberg ,  Gustav Pellijeff ,  Leda Henriquez

IPC分类号： A61B5/04 ,  A61N1/36 ,  H05K13/00

CPC分类号： A61N1/05 ,  A61N1/056 ,  A61N1/086 ,  A61N1/3718 ,  Y10T29/49002

摘要： A medical implantable lead adapted to be implanted into a human or animal body for monitoring and/or controlling of an organ inside the body has a fixation in a distal end, which is adapted to fix a distal end of the lead to the organ, an electrode member in the distal end adapted to be in contact with tissue of the organ and receive and/or transmit electrical signals from and/or to the organ, and at least one electrically conducting coil, which includes one or more electrically conducting helical wires and that is adapted to connect the electrode member in the distal end with a monitoring and/or controlling device in a proximal end of the lead. One or more of the individual wires of the coil has a wire core that is provided with a surrounding electrically insulating layer, which in turn is provided with a surrounding electrically conducting shield layer, and the coil is close lapped such that electrically conducting shield layers of adjacent loops of the coil are in electrical contact with each other.

摘要翻译： 适于植入人体或动物体内的用于监测和/或控制体内器官的医用可植入引线具有在远端固定，其适于将引线的远端固定到器官， 远端中的电极构件适于与器官的组织接触并且接收和/或传送来自器官和/或器官的电信号，以及至少一个导电线圈，其包括一个或多个导电螺旋线和 其适于将远端中的电极构件与引线的近端中的监视和/或控制装置连接。 线圈的一条或多条单独的线具有线芯，该芯线设置有环绕的电绝缘层，该电绝缘层又设置有环绕的导电屏蔽层，并且线圈被紧密地重叠，使得导电屏蔽层 线圈的相邻环彼此电接触。

公开(公告)号：US07860581B2

公开(公告)日：2010-12-28

申请号：US12090982

申请日：2005-10-31

申请人： Johan Eckerdal ,  Kenneth Dahlberg

发明人： Johan Eckerdal ,  Kenneth Dahlberg

IPC分类号： A61N1/05

CPC分类号： A61N1/056 ,  A61N1/0573

摘要： An implantable lead for delivering electrical stimuli to a human heart has a stimulating electrode for transmitting electrical stimuli to the myocardium after implantation, and a mapping electrode for use during implantation. The mapping electrode is configured to deliver electrical stimuli to the heart and to sense intrinsic cardiac activity, for the purpose of finding a suitable fixation position in the myocardium. During the implantation procedure, the mapping electrode is electrically connected to the conductor. The lead is configured to electrically disconnect the mapping electrode from the conductor after a suitable fixation position has been determined.

摘要翻译： 用于将电刺激递送到人的心脏的可植入引线具有刺激电极，用于在植入后将电刺激传输到心肌，以及用于植入期间的映射电极。 映射电极被配置为向心脏递送电刺激并感测内在的心脏活动，以便在心肌中找到合适的固定位置。 在植入过程期间，映射电极电连接到导体。 引线构造成在已经确定了合适的固定位置之后电连接映射电极与导体。

公开(公告)号：US07146208B2

公开(公告)日：2006-12-05

申请号：US10396958

申请日：2003-03-25

申请人： Nils Holmström ,  Anna Norlin ,  Kenneth Dahlberg ,  Martin Obel

发明人： Nils Holmström ,  Anna Norlin ,  Kenneth Dahlberg ,  Martin Obel

IPC分类号： A61B5/053 ,  A61N1/365

CPC分类号： A61B5/0535 ,  A61N1/3627 ,  A61N1/36521 ,  A61N1/3684

摘要： A heart monitoring device has a control circuit, the control circuit being adapted to be electrically connected to electrode surfaces arranged at two different positions of the heart. The control circuit derives an impedance value indicative of the impedance between the electrode surfaces. Furthermore, the control circuit is arranged to determine and monitor a relationship between a positive rate of change and a negative rate of change of the impedance value. The device can, in particular, be used to detect and treat a systolic dysfunction of a heart.

摘要翻译： 心脏监测装置具有控制电路，所述控制电路适于电连接到布置在心脏两个不同位置处的电极表面。 控制电路导出指示电极表面之间的阻抗的阻抗值。 此外，控制电路被布置成确定和监测正的变化率和阻抗值的负的变化率之间的关系。 该装置特别可用于检测和治疗心脏的收缩功能障碍。

公开(公告)号：US07058452B2

公开(公告)日：2006-06-06

申请号：US10220538

申请日：2001-01-29

申请人： Kenneth Dahlberg

发明人： Kenneth Dahlberg

IPC分类号： A61N1/372

CPC分类号： A61N1/3752 ,  Y10S439/909

摘要： In a process for manufacturing a female connector for a pacemaker, a tubular ceramic insert is formed with a longitudinal bore and with two radial holes connecting internal contact surfaces with external contact surfaces. The radial holes are filled with conductive material and the internal and external contact surfaces are metallized. The ceramic insert is covered with a layer of metal except for an area around each of the external contact surfaces.

摘要翻译： 在用于制造起搏器的阴连接器的过程中，管状陶瓷插入件形成有纵向孔，并且具有将内部接触表面与外部接触表面连接的两个径向孔。 径向孔填充有导电材料，并且内部和外部接触表面被金属化。 除了围绕每个外部接触表面的区域之外，陶瓷插件被一层金属覆盖。