公开(公告)号：US20110076316A1

公开(公告)日：2011-03-31

申请号：US12682218

申请日：2007-10-08

申请人： Sureshan Sivananthan ,  Patrick Hans Warnke ,  Eugene Sherry ,  Krish Gopalakrishnan

发明人： Sureshan Sivananthan ,  Patrick Hans Warnke ,  Eugene Sherry ,  Krish Gopalakrishnan

IPC分类号： A61K35/12 ,  A61F2/02 ,  A61F2/28 ,  A61K9/00 ,  C12N5/071 ,  A61K38/02 ,  A61K38/18 ,  A61K38/48 ,  A61P19/02 ,  A61P19/08 ,  A61P43/00 ,  B29C35/08

CPC分类号： A61F2/28 ,  A61F2/30907 ,  A61F2002/2817 ,  A61F2002/2835 ,  A61F2002/30092 ,  A61F2002/3028 ,  A61F2002/3092 ,  A61F2002/3097 ,  A61F2002/30985 ,  A61F2210/0014 ,  A61F2230/0063 ,  A61F2310/00011 ,  A61F2310/00179 ,  A61F2310/00329

摘要： The present invention provides implantable receptacle devices (and methods) for use in bone and tissue regeneration which provide immediate structural stability and strength to a zone where tissue regeneration is required. By virtue of their size, shape and construction, the devices are scalable, modular, structurally stable, self-stacking in three dimensions, can be aggregated to an anatomically accurate shape, and hold various materials delivered into the implant area so as to create a highly regenerative micro-environment. They can be implanted via less invasive surgical procedures, and because they act as external scaffolding as well as being imbedded as an integral part of a matrix for the effective and rapid regeneration of bone and cartilage in vivo, they may provide significant advantages to patients or subjects in terms of reduced pain, faster healing and fewer complications.

摘要翻译： 本发明提供了用于骨组织再生的可植入容器装置（和方法），其为需要组织再生的区域提供立即的结构稳定性和强度。 由于它们的尺寸，形状和结构，这些装置是可扩展的，模块化的，结构稳定的，三维自我堆叠的，可以聚集成解剖学上准确的形状，并且将各种材料传送到植入区域中，以便产生 高度再生的微环境。 它们可以通过较少侵入性的外科手术植入，并且由于它们作为外部脚手架，并且被嵌入作为用于体内骨和软骨的有效和快速再生的基质的组成部分，它们可以为患者或 受试者减少疼痛，愈合愈合和并发症少。