公开(公告)号：US07106422B2

公开(公告)日：2006-09-12

申请号：US10875774

申请日：2004-06-24

Applicant: Jui-Feng Huang ,  Lung-Pin Chung ,  Kuo-Hua Yang ,  Ai-Ling Lin

Inventor： Jui-Feng Huang ,  Lung-Pin Chung ,  Kuo-Hua Yang ,  Ai-Ling Lin

IPC: G01B11/00

CPC classification number: G01S7/487 ,  G01C3/08 ,  G01C17/30 ,  G01S7/4868 ,  G01S17/023 ,  G01S17/10

Abstract: A Rangefinder capable of long and short distance measurement in company with compass measurement. The rangefinder includes distance measurement unit, a compass sensing unit and a processor. The rangefinder can selectively execute a comparison mode or a gain mode. The comparison mode is executed during short-distance measurement and the gain mode is executed during long-distance measurement. The compass measurement unit senses a terrestrial magnetism to obtain first and second magnetic sensing signals. The processor estimates a distance between the target and the rangefinder according to the measurement signal from the distance measurement unit and determines a compass orientation of the target according to the first and second magnetic sensing signals.

Abstract translation: 一种距离测距仪，能够进行长距离和短距离测量，并配有罗盘测量。 测距仪包括距离测量单元，罗盘感测单元和处理器。 测距仪可以选择性地执行比较模式或增益模式。 在短距离测量期间执行比较模式，并且在长距离测量期间执行增益模式。 罗盘测量单元感测地磁以获得第一和第二磁感测信号。 处理器根据距离测量单元的测量信号估计目标和测距仪之间的距离，并根据第一和第二磁感测信号确定目标的罗盘方位。

公开(公告)号：US20050185168A1

公开(公告)日：2005-08-25

申请号：US10912358

申请日：2004-08-05

Applicant: Peng-Fei Song ,  Chih-Wei Hung ,  Pi-Yao Chien ,  Kuo-Hua Yang

Inventor： Peng-Fei Song ,  Chih-Wei Hung ,  Pi-Yao Chien ,  Kuo-Hua Yang

IPC: G01C3/00 ,  G01C3/06 ,  G01C3/08 ,  G01C3/20 ,  G01C15/00 ,  G01S1/00 ,  G01S17/02 ,  G01S17/10 ,  H04B7/185

CPC classification number: G01C15/002 ,  G01C3/06 ,  G01S17/023 ,  G01S17/10

Abstract: A multifunction rangefinder capable of measuring distance, compass location and altitude. A distance measurement unit capable of long and short distance measurements transmits a light beam to a target, receives a reflected light from the target and outputs a distance measurement signal. A compass measurement unit measures terrestrial magnetism and outputs a compass measurement signal. An altitude measurement unit measures atmospheric pressure to generate an altitude measurement signal. A microprocessor calculates a distance between the target and the multifunction rangefinder, altitude and the compass location of the target according to the distance, altitude and compass measurement signals respectively.

Abstract translation: 能够测量距离，罗盘位置和高度的多功能测距仪。 能够进行长距离和短距离测量的距离测量单元将光束发射到目标，接收来自目标的反射光并输出距离测量信号。 罗盘测量单元测量地磁并输出罗盘测量信号。 高度测量单元测量大气压力以产生高度测量信号。 微处理器根据距离，高度和罗盘测量信号分别计算目标和多功能测距仪之间的距离，高度和目标的罗盘位置。

公开(公告)号：US20050151956A1

公开(公告)日：2005-07-14

申请号：US10756053

申请日：2004-01-12

Applicant: Pie-Yau Chien ,  Dong Huang ,  Kuo-Hua Yang ,  Dan Duan

Inventor： Pie-Yau Chien ,  Dong Huang ,  Kuo-Hua Yang ,  Dan Duan

IPC: G01C3/08 ,  G01S7/491 ,  G01S17/36

CPC classification number: G01S17/36 ,  G01S7/4915

Abstract: An apparatus for precise distance measurement has a multiple frequency generator, a laser transmitter, an optical receiver, a first measuring unit, a second measuring unit and a central processing unit. The laser transmitter outputs a light signal to a target, and the optical receiver receives the reflected light signal and mixes the base frequency signal from the multiple frequency generator and the reflected light signal and further outputs an measurement signal to the first and second measuring units. The first and second measuring units calculate respectively a time difference and a phase difference between the light signal and the reflected light signal. The central processing unit is connected to the first and second measuring units to calculate a precise distance by the time and the phase difference.

Abstract translation: 用于精确距离测量的装置具有多频发生器，激光发射器，光接收器，第一测量单元，第二测量单元和中央处理单元。 激光发射器将光信号输出到目标，并且光接收器接收反射光信号并混合来自多频发生器的基频信号和反射光信号，并进一步向第一和第二测量单元输出测量信号。 第一和第二测量单元分别计算光信号和反射光信号之间的时间差和相位差。 中央处理单元连接到第一和第二测量单元以计算时间和相位差之间的精确距离。

公开(公告)号：US20130078304A1

公开(公告)日：2013-03-28

申请号：US13247302

申请日：2011-09-28

Applicant: HSIEN-JEN HSIEH ,  KUO-HUA YANG ,  CHIH-SHENG YANG ,  YU-CHENG WEI ,  CHUNG-HSUAN LU

Inventor： HSIEN-JEN HSIEH ,  KUO-HUA YANG ,  CHIH-SHENG YANG ,  YU-CHENG WEI ,  CHUNG-HSUAN LU

IPC: A61K31/519 ,  A61P25/00 ,  A61K9/24 ,  A61K9/52 ,  A61K9/30 ,  A61K9/32

CPC classification number: A61K31/519 ,  A61K9/1676 ,  A61K9/209 ,  A61K31/437 ,  A61K2300/00

Abstract: The invention relates to a controlled-release formulation for preventing and/or treating sleep disorders comprising Zaleplon or a pharmaceutically acceptable salt thereof in immediate release form and Zolpidem or a pharmaceutically acceptable salt thereof in sustained release form, wherein Zaleplon or a pharmaceutically acceptable salt thereof and Zolpidem or a pharmaceutically acceptable salt thereof are released in two phases where the first phase is a immediate release phase of Zaleplon or a pharmaceutically acceptable salt thereof and the second phase is a sustained release phase of Zolpidem or a pharmaceutically acceptable salt thereof.

Abstract translation: 本发明涉及一种用于预防和/或治疗睡眠障碍的控释制剂，其包括立即释放形式的扎利波隆或其药学上可接受的盐和唑吡旦或其药学上可接受的盐，其为缓释形式，其中扎利波隆或其药学上可接受的盐 和唑吡旦或其药学上可接受的盐在两相中释放，其中第一相是扎来普隆或其药学上可接受的盐的即时释放阶段，第二相是唑吡旦或其药学上可接受的盐的持续释放期。

公开(公告)号：US07184131B2

公开(公告)日：2007-02-27

申请号：US10912358

申请日：2004-08-05

Applicant: Peng-Fei Song ,  Chih-Wei Hung ,  Pi-Yao Chien ,  Kuo-Hua Yang

Inventor： Peng-Fei Song ,  Chih-Wei Hung ,  Pi-Yao Chien ,  Kuo-Hua Yang

IPC: G01C3/08

CPC classification number: G01C15/002 ,  G01C3/06 ,  G01S17/023 ,  G01S17/10

Abstract: A multifunction rangefinder capable of measuring distance, compass location and altitude. A distance measurement unit capable of long and short distance measurements transmits a light beam to a target, receives a reflected light from the target and outputs a distance measurement signal. A compass measurement unit measures terrestrial magnetism and outputs a compass measurement signal. An altitude measurement unit measures atmospheric pressure to generate an altitude measurement signal. A microprocessor calculates a distance between the target and the multifunction rangefinder, altitude and the compass location of the target according to the distance, altitude and compass measurement signals respectively.

Abstract translation: 能够测量距离，罗盘位置和高度的多功能测距仪。 能够进行长距离和短距离测量的距离测量单元将光束发射到目标，接收来自目标的反射光并输出距离测量信号。 罗盘测量单元测量地磁并输出罗盘测量信号。 高度测量单元测量大气压力以产生高度测量信号。 微处理器根据距离，高度和罗盘测量信号分别计算目标和多功能测距仪之间的距离，高度和目标的罗盘位置。

公开(公告)号：US20050154549A1

公开(公告)日：2005-07-14

申请号：US10756054

申请日：2004-01-12

Applicant: Ai-Ling Lin ,  Kuo-Hua Yang

Inventor： Ai-Ling Lin ,  Kuo-Hua Yang

IPC: G01C1/02 ,  G01C17/32 ,  G01C17/38 ,  G01P21/00

CPC classification number: G01C17/38

Abstract: A method of measuring the azimuth and resetting to zero azimuth automatically is disclosed. Multiple azimuths in longitudinal and latitudinal orientations are sampled by two orthogonal magnetic sensors installed in an azimuth meter, and then are output by corresponding first and second sine wave signals. These two sine wave signals are normalized by adjusting them to be of equal amplitude. The maximum and minimum values of the normalized sine wave signals are used to compute the average values of the respective normalized sine wave signals being of equal amplitude on the positive and negative sides. The resultant sine wave signals serve as the zero reference values for comparison with subsequently taken measuring signals to yield the actual azimuth. The numerical computation for the azimuth can be performed by a microprocessor with accuracy and high speed.

Abstract translation: 公开了一种自动测量方位和复位到零方位的方法。 通过安装在方位计上的两个正交磁传感器对纵向和纬向的多个方位进行采样，然后通过相应的第一和第二正弦波信号输出。 这两个正弦波信号通过将它们调整为相等幅度来进行归一化。 归一化正弦波信号的最大值和最小值用于计算在正侧和负侧具有相等振幅的相应归一化正弦波信号的平均值。 所得的正弦波信号用作零参考值，用于与随后测量的信号进行比较以产生实际的方位角。 方位角的数值计算可以由微处理器以精确，高速度进行。

公开(公告)号：US20050129719A1

公开(公告)日：2005-06-16

申请号：US10736307

申请日：2003-12-15

Applicant: Yu-Fang Hu ,  Yao-Kun Huang ,  Huei-Tang Lin ,  Kuo-Hua Yang

Inventor： Yu-Fang Hu ,  Yao-Kun Huang ,  Huei-Tang Lin ,  Kuo-Hua Yang

IPC: A61K31/4745 ,  A61K31/695 ,  A61K47/10 ,  A61K47/24 ,  A61K9/00

CPC classification number: A61K9/0019 ,  A61K31/4745 ,  A61K31/695 ,  A61K47/10 ,  A61K47/24

Abstract: The present application relates to a concentrated emulsion formulation for water-insoluble silatecan comprising silatecan of 0.01-1.0% (W/W), phospholipid of 4.79-75% (W/W); propylene glycol of 24.79˜95% (W/W); optional ethanol of 0.1-40% (W/W); optional surfactant of 0.1-10% (W/W), especially Tween® 80. The present application also relates to a method for manufacturing the concentrated emulsion formulation.

Abstract translation: 本申请涉及含有0.01-1.0％（W / W）硅酸盐，4.79-75％（W / W）磷脂的水不溶性硅酸盐的浓缩乳液制剂; 丙二醇为24.79〜95％（W / W）; 可选乙醇为0.1-40％（W / W）; 0.1-10％（W / W）的任选的表面活性剂，特别是80。本申请还涉及一种制备浓缩乳液制剂的方法。

公开(公告)号：US09308203B2

公开(公告)日：2016-04-12

申请号：US12570656

申请日：2009-09-30

Applicant: Kuo-Hua Yang ,  Yung-Jin Lee ,  Li-Chin Lin

Inventor： Kuo-Hua Yang ,  Yung-Jin Lee ,  Li-Chin Lin

IPC: A61K9/70 ,  A61K47/14 ,  A61K31/496

CPC classification number: A61K31/496 ,  A61K9/7023 ,  A61K9/7061 ,  A61K47/14

Abstract: Disclosed is a pressure-sensitive adhesive matrix patch device for treatment or prevention of fungal toenails or fingernails or foot infections comprising an antifungal agent or two or more antifungals in combination and adhesively secured to a dorsal site of an infected palm or foot, rather than an area of infection and surrounding skin. A method for the transdermal treatment or prevention of fungal toenails or fingernails or foot infections with an antifungal agent is also disclosed, the method comprising adhesively securing to a dorsal site of an infected palm or foot a pressure-sensitive adhesive matrix patch device for a time sufficient to deliver an effective amount of the antifungal agent to an area of infection.

Abstract translation: 公开了一种用于治疗或预防真菌趾甲或指甲或足部感染的压敏粘合剂基质贴片装置，其包含抗真菌剂或两种或更多种抗真菌剂的组合，并且粘附地固定到感染的手掌或足部的背部，而不是 感染区域和周围皮肤。 还公开了用抗真菌剂透皮治疗或预防真菌脚趾甲或指甲或足部感染的方法，所述方法包括将感染的手掌或足部的背部部位粘合固定一段时间的压敏粘合剂基质贴片装置 足以将有效量的抗真菌剂递送至感染区域。

公开(公告)号：US08641900B2

公开(公告)日：2014-02-04

申请号：US12939460

申请日：2010-11-04

Applicant: Shou-Min Huang ,  Chun-Wei Liu ,  Kuo-Hua Yang

Inventor： Shou-Min Huang ,  Chun-Wei Liu ,  Kuo-Hua Yang

IPC: A61K9/50

CPC classification number: A61K9/1682 ,  A61K9/1694 ,  A61K9/19 ,  A61K9/5089

Abstract: A method and a device for continuously preparing microspheres, and a collection unit thereof are provided. The collection unit for collecting microspheres in the solution comprises a tank and a first plate. The first plate is removably disposed in the tank. The first plate, when lay across the tank, has its two ends came in contact with the sidewall of the tank so as to divide the tank into a first chamber and a second chamber. The tank has an outlet located in the second chamber. After the solution with microspheres are input to the first chamber of the tank, the microspheres are deposited around the first plate, and the solution is caused to pass through or over the first plate to the second chamber and output from the outlet.

Abstract translation: 提供一种用于连续制备微球体的方法和装置及其收集单元。 用于在溶液中收集微球的收集单元包括罐和第一板。 第一板可拆卸地设置在罐中。 第一块板在横跨箱体时，其两端与箱体的侧壁接触，以将箱体分成第一室和第二室。 该罐具有位于第二室中的出口。 在将微球的溶液输入到罐的第一室之后，微球沉积在第一板周围，使溶液通过或超过第一板到第二室并从出口输出。

公开(公告)号：US08470365B2

公开(公告)日：2013-06-25

申请号：US12846476

申请日：2010-07-29

Applicant: Li-Heng Pao ,  Nion-Heng Shiao ,  Kuo-Hua Yang ,  Jui-Ming Chou

Inventor： Li-Heng Pao ,  Nion-Heng Shiao ,  Kuo-Hua Yang ,  Jui-Ming Chou

IPC: A61K9/20

CPC classification number: A61K31/497 ,  A61K9/2077 ,  A61K9/209 ,  A61K9/2866 ,  A61K31/166 ,  A61K2300/00

Abstract: This invention relates to a process for preparing a pharmaceutical composition comprising four antitubercular drugs: rifampin or a pharmaceutically acceptable salt thereof, isoniazid or a pharmaceutically acceptable salt thereof, pyrazinamide or a pharmaceutically acceptable salt thereof and ethambutol or a pharmaceutically acceptable salt thereof, wherein rifampin and isoniazid are in separate layers. The invention also provides a pharmaceutical composition prepared therefrom having advantageous stability and bioavailability.

Abstract translation: 本发明涉及一种制备药物组合物的方法，其包含四种抗结核药物：利福平或其药学上可接受的盐，异烟肼或其药学上可接受的盐，吡嗪酰胺或其药学上可接受的盐和乙胺丁醇或其药学上可接受的盐，其中利福平 异烟肼分开。 本发明还提供由其制备的药物组合物，其具有有利的稳定性和生物利用度。