公开(公告)号：US20070196918A1

公开(公告)日：2007-08-23

申请号：US11694687

申请日：2007-03-30

申请人： Chauncey Sayre ,  Francisco Silva ,  Kwok-Yuen Pau

发明人： Chauncey Sayre ,  Francisco Silva ,  Kwok-Yuen Pau

IPC分类号： C12N5/08 ,  C12N15/09

CPC分类号： C12N5/0611 ,  C12N2500/25 ,  C12N2500/32 ,  C12N2500/38 ,  C12N2501/11 ,  C12N2501/115 ,  C12N2501/119 ,  C12N2501/13 ,  C12N2501/235 ,  C12N2501/392

摘要： Methods for therapeutically programming human adult stem cells into pluripotent cells are provided. Cell therapeutically programmed from adult testicular cells are disclosed. The therapeutically reprogrammed cells are suitable for cellular regenerative therapy and have the potential to differentiate into more committed cell lineages.

摘要翻译： 提供了将人成体干细胞治疗性编程成多能细胞的方法。 公开了从成年睾丸细胞治疗编程的细胞。 治疗重新编程的细胞适合于细胞再生治疗，并且具有分化成更确定的细胞谱系的潜力。

公开(公告)号：US20070020759A1

公开(公告)日：2007-01-25

申请号：US11488362

申请日：2006-07-17

申请人： Chauncey Sayre ,  Francisco Silva ,  Kwok-Yuen Pau

发明人： Chauncey Sayre ,  Francisco Silva ,  Kwok-Yuen Pau

IPC分类号： C12N5/08 ,  C12N15/09

CPC分类号： C12N5/0611 ,  C12N2500/25 ,  C12N2500/32 ,  C12N2500/38 ,  C12N2501/11 ,  C12N2501/115 ,  C12N2501/13 ,  C12N2501/235 ,  C12N2501/392

摘要： Pluripotent therapeutically programmed cells and methods for making such cells are provided. The pluripotent therapeutically programmed cells are post-natal stem cells which have been matured such that they represent either a more differentiated state or a less differentiated state after contact with stimulatory factors. The pluripotent therapeutically reprogrammed cells are suitable for cellular regenerative therapy and have the potential to differentiate into more committed cell lineages. Also disclosed are culture media for therapeutically reprogramming post-natal stem cells.

摘要翻译： 提供多能治疗程序细胞和制备这种细胞的方法。 多能治疗程序性细胞是已经成熟的产后干细胞，使得它们在与刺激因子接触后表现出更加分化的状态或较差的状态。 多能治疗重新编程的细胞适合于细胞再生治疗，并具有分化为更有决心的细胞谱系的潜力。 还公开了用于治疗重新编程产后干细胞的培养基。