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公开(公告)号：US09751918B2
公开(公告)日：2017-09-05
申请号：US12357622
申请日：2009-01-22
申请人： Lars Erik Berglund , Torben Ellebaek Petersen , Sergey Nikolaevich Fedosov , Ebba Nexo , Niels Bech Laursen , Erik Ostergaard Jensen
发明人： Lars Erik Berglund , Torben Ellebaek Petersen , Sergey Nikolaevich Fedosov , Ebba Nexo , Niels Bech Laursen , Erik Ostergaard Jensen
IPC分类号： C07K14/47 , C12N15/82 , A61K31/7056 , A61K38/16 , A61K47/48 , C07K14/415 , C12N5/071 , A61K38/00
CPC分类号： C07K14/47 , A61K31/7056 , A61K38/00 , A61K38/168 , A61K47/551 , C07K14/415 , C12N5/0602 , C12N15/8257 , C12N2500/38
摘要： The present invention relates to the use of transgenic plants for the expression of vitamin B12 (cobalamin) binding proteins. Plant cells are transformed with nucleotide sequences adapted for expression and secretion of vitamin B12 binding proteins. The present invention also relates to the use of recombinant vitamin B12 binding proteins from plants in analytical tests and treatment of vitamin B12 deficiency. Also disclosed is a method for purification of recombinant vitamin B12 binding proteins.
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公开(公告)号：US09523014B2
公开(公告)日：2016-12-20
申请号：US11913891
申请日：2006-05-09
IPC分类号： C08B11/20 , C08L3/12 , C04B40/00 , C09D101/28 , A61K47/38 , C04B24/38 , C04B28/14 , C08B11/193 , C08J3/12 , C08L1/28 , C04B103/44 , C04B111/00
CPC分类号： C09D101/28 , A61K47/38 , C04B24/383 , C04B28/14 , C04B40/0039 , C04B2103/44 , C04B2111/00482 , C08B11/193 , C08B11/20 , C08J3/12 , C08J3/124 , C08J2301/26 , C08J2301/28 , C08L1/28 , C04B20/026 , C04B2103/404
摘要： The invention relates to a process for grinding cellulose ether comprising the steps of: a) grinding a cellulose ether comprising 20 to 90 wt % of water, based on the total weight of cellulose ether and water, and a cationic surfactant in a mill; and b) optionally drying the mixture while grinding, prior to or following the step of grinding.
摘要翻译： 本发明涉及一种研磨纤维素醚的方法，包括以下步骤：a）研磨基于纤维素醚和水的总重量的20至90重量％的水和在研磨机中的阳离子表面活性剂的纤维素醚; 和b）在研磨步骤之前或之后任选地在混合物的同时干燥混合物。
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公开(公告)号：US20100184642A1
公开(公告)日：2010-07-22
申请号：US12357622
申请日：2009-01-22
申请人： Lars Erik Berglund , Torben Ellebaek Petersen , Sergey Nikolaevich Fedosov , Ebba Nexo , Niels Bech Laursen , Erik Ostergaard Jensen
发明人： Lars Erik Berglund , Torben Ellebaek Petersen , Sergey Nikolaevich Fedosov , Ebba Nexo , Niels Bech Laursen , Erik Ostergaard Jensen
CPC分类号： C07K14/47 , A61K31/7056 , A61K38/00 , A61K38/168 , A61K47/551 , C07K14/415 , C12N5/0602 , C12N15/8257 , C12N2500/38
摘要： The present invention relates to the use of transgenic plants for the expression of vitamin B12 (cobalamin) binding proteins. Plant cells are transformed with nucleotide sequences adapted for expression and secretion of vitamin B12 binding proteins. The present invention also relates to the use of recombinant vitamin B12 binding proteins from plants in analytical tests and treatment of vitamin B12 deficiency. Also disclosed is a method for purification of recombinant vitamin B12 binding proteins.
摘要翻译： 本发明涉及转基因植物用于表达维生素B12（钴胺素）结合蛋白的用途。 用适于维生素B12结合蛋白的表达和分泌的核苷酸序列转化植物细胞。 本发明还涉及来自植物的重组维生素B12结合蛋白在维生素B12缺乏症的分析测试和治疗中的用途。 还公开了重组维生素B12结合蛋白的纯化方法。
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公开(公告)号：US20080207893A1
公开(公告)日：2008-08-28
申请号：US11913891
申请日：2006-05-09
IPC分类号： C08B11/20
CPC分类号： C09D101/28 , A61K47/38 , C04B24/383 , C04B28/14 , C04B40/0039 , C04B2103/44 , C04B2111/00482 , C08B11/193 , C08B11/20 , C08J3/12 , C08J3/124 , C08J2301/26 , C08J2301/28 , C08L1/28 , C04B20/026 , C04B2103/404
摘要： The invention relates to a process for grinding cellulose ether comprising the steps of: a) grinding a cellulose ether comprising 20 to 90 wt % of water, based on the total weight of cellulose ether and water, and a cationic surfactant in a mill; and b) optionally drying the mixture while grinding, prior to or following the step of grinding.
摘要翻译： 本发明涉及一种研磨纤维素醚的方法，包括以下步骤：a）研磨基于纤维素醚和水的总重量的20至90重量％的水和在研磨机中的阳离子表面活性剂的纤维素醚; 和b）在研磨步骤之前或之后任选地在混合物的同时干燥混合物。
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