-
公开(公告)号：US20140148489A1
公开(公告)日：2014-05-29
申请号：US14112663
申请日：2012-04-17
申请人： Laurent Provins , Yannick Quesnel
发明人： Laurent Provins , Yannick Quesnel
IPC分类号： C07D513/04
CPC分类号： C07D513/04 , A61K31/433
摘要： The present invention relates to 2-oxo-1-imidazolidinyl imidazothiadiazole derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
摘要翻译： 本发明涉及2-氧代-1-咪唑烷基咪唑并噻二唑衍生物，其制备方法，含有它们的药物组合物及其作为药物的用途。
-
公开(公告)号：US08957218B2
公开(公告)日：2015-02-17
申请号：US14112663
申请日：2012-04-17
申请人： Laurent Provins , Yannick Quesnel
发明人： Laurent Provins , Yannick Quesnel
IPC分类号： C07D417/14 , A61K31/433 , C07D513/04
CPC分类号： C07D513/04 , A61K31/433
摘要： The present invention relates to 2-oxo-1-imidazolidinyl imidazothiadiazole derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
摘要翻译： 本发明涉及2-氧代-1-咪唑烷基咪唑并噻二唑衍生物，其制备方法，含有它们的药物组合物及其作为药物的用途。
-
3.发明申请Compounds Comprising a Lactam or a Lactam Derivative Moiety, Processes for Making Them, and Their Uses 失效包含内酰胺或内酰胺衍生物的化合物，其制备方法及其用途公开(公告)号：US20090023708A1
公开(公告)日：2009-01-22
申请号：US12091380
申请日：2006-10-25
申请人： Sylvain Celanire , Luc Quere , Frederic Denonne , Laurent Provins
发明人： Sylvain Celanire , Luc Quere , Frederic Denonne , Laurent Provins
IPC分类号： A61K31/55 , C07D401/14 , A61K31/454 , C07D403/14 , A61K31/421 , C07D263/20 , A61K31/496 , A61K31/4025 , C07D403/12
CPC分类号： C07D207/26 , C07D205/08 , C07D207/09 , C07D207/24 , C07D207/277 , C07D209/54 , C07D211/76 , C07D223/10 , C07D263/22 , C07D295/088 , C07D487/10
摘要： The present invention relates to compounds of formula (I) comprising a lactam or a lactam derivative moiety, processes for preparing them, pharmaceutical compositions comprising said compounds and their uses as pharmaceuticals.
摘要翻译： 本发明涉及包含内酰胺或内酰胺衍生物部分的式（I）化合物，其制备方法，包含所述化合物的药物组合物及其作为药物的用途。
-
公开(公告)号：US20110098300A1
公开(公告)日：2011-04-28
申请号：US12995084
申请日：2009-06-02
IPC分类号： A61K31/5377 , C07D211/60 , C07D413/12 , A61K31/4453 , A61P9/10 , A61P25/00 , A61P25/18 , A61P25/28
CPC分类号： C07D295/192 , C07D211/38 , C07D211/46 , C07D213/75 , C07D279/12 , C07D295/096
摘要： The present invention relates to compounds of formula (I) comprising a cyclobutoxy group, processes for preparing them, pharmaceutical compositions comprising said compounds and their use as pharmaceuticals, useful for the treatment and prevention of diseases or pathological conditions of the central nervous system including mild-cognitive impairments, Alzheimer's disease, learning and; memory disorders, cognitive disorders, attention deficit disorder, attention-deficit hyperactivity disorder, Parkinson's disease, schizophrenia, dementia, depression, epilepsy, seizures, convulsions, sleep/wake and arousal/vigilance disorders such as hypersomnia and narcolepsy, pain and/or obesity.
摘要翻译： 本发明涉及包含环丁氧基的式（I）化合物，其制备方法，包含所述化合物的药物组合物及其作为药物的用途，可用于治疗和预防中枢神经系统疾病或病理状况，包括温和 - 认知障碍，阿尔茨海默病，学习和; 记忆障碍，认知障碍，注意力缺陷障碍，注意力缺陷多动障碍，帕金森病，精神分裂症，痴呆，抑郁症，癫痫，癫痫发作，抽搐，睡眠/唤醒和觉醒/警惕性障碍，如睡眠过多和发作性睡病，疼痛和/或肥胖 。
-
公开(公告)号：US20060074068A1
公开(公告)日：2006-04-06
申请号：US10511660
申请日：2003-03-29
IPC分类号： A61K31/506 , A61K31/505 , C07D403/02
CPC分类号： C07D239/42 , C07D239/48 , C07D239/50 , C07D239/60 , C07D401/04 , C07D403/04 , C07D405/12 , C07D409/12 , C07D471/04 , C07D487/04
摘要： The present invention concerns chemical compounds combining affinity and antagonism against the human m3 muscarinic receptor with activity as selective phosphodiesterase IV (PDE IV) inhibitors, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
-
6.发明授权Chemical compounds with dual activity, processes for their preparation and pharmaceutical compositions 失效具有双重活性的化合物，其制备方法和药物组合物公开(公告)号：US07544675B2
公开(公告)日：2009-06-09
申请号：US10511660
申请日：2003-03-29
IPC分类号： C07D239/48 , C07D239/42 , A61K31/505
CPC分类号： C07D239/42 , C07D239/48 , C07D239/50 , C07D239/60 , C07D401/04 , C07D403/04 , C07D405/12 , C07D409/12 , C07D471/04 , C07D487/04
摘要： The present invention concerns chemical compounds combining affinity and antagonism against the human m3 muscarinic receptor with activity as selective phosphodiesterase IV (PDE IV) inhibitors, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
摘要翻译： 本发明涉及结合亲和力拮抗人M3毒蕈碱受体的化合物，其具有作为选择性磷酸二酯酶IV（PDE IV）抑制剂的活性，其制备方法，含有它们的药物组合物及其作为药物的用途。
-
7.发明授权Compounds comprising a lactam or a lactam derivative moiety, processes for making them, and their uses 失效包含内酰胺或内酰胺衍生物部分的化合物，其制备方法及其用途公开(公告)号：US07943605B2
公开(公告)日：2011-05-17
申请号：US12091380
申请日：2006-10-25
申请人： Sylvain Celanire , Luc Quere , Frédéric Denonne , Laurent Provins
发明人： Sylvain Celanire , Luc Quere , Frédéric Denonne , Laurent Provins
IPC分类号： A61K31/395 , A61K31/55 , A61K31/541 , A61K31/5355 , A61K31/496 , A61K31/438 , A61K31/4439 , A61K31/4025 , C07D401/14 , C07D403/14 , C07D417/14 , C07D413/14 , C07D221/20 , C07D215/06 , C07D209/54 , C07D207/12
CPC分类号： C07D207/26 , C07D205/08 , C07D207/09 , C07D207/24 , C07D207/277 , C07D209/54 , C07D211/76 , C07D223/10 , C07D263/22 , C07D295/088 , C07D487/10
摘要： The present invention relates to compounds of formula (I) comprising a lactam or a lactam derivative moiety, processes for preparing them, pharmaceutical compositions comprising said compounds and their uses as pharmaceuticals.
摘要翻译： 本发明涉及包含内酰胺或内酰胺衍生物部分的式（I）化合物，其制备方法，包含所述化合物的药物组合物及其作为药物的用途。
-
公开(公告)号：US20100009969A1
公开(公告)日：2010-01-14
申请号：US12375288
申请日：2007-07-17
IPC分类号： A61K31/55 , A61K31/5377 , C07D513/04 , C07D415/00
CPC分类号： C07D277/60 , C07D277/66 , C07D513/04
摘要： The present invention relates to compounds comprising fused oxazole or thiazole derivatives of formula (I), processes for preparing them, pharmaceutical compositions comprising said compounds and their uses as H3-receptor ligands, wherein A is a cyclic amine which is linked to the propylene group via an amino nitrogen; B is selected from the group consisting of heteroaryl, 5-8-membered heterocycloalkyl, 5-8-membered cycloalkyl; X is either N or CH; Y is either O or S.
摘要翻译： 本发明涉及包含式（I）的稠合唑或噻唑衍生物，其制备方法，包含所述化合物的药物组合物及其用作H3受体配体的化合物的化合物，其中A是与丙烯基团连接的环状胺 通过氨基氮; B选自杂芳基，5-8元杂环烷基，5-8元环烷基; X是N或CH; Y是O或S.
-
-
-
-
-
-
-
搜索结果
8 条记录 (耗时 0.018 秒)
